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Predicting the Severity of Post-cesarean Wound Infections Using Serum Procalcitonin Levels

NCT ID: NCT03223233

Last Updated: 2017-10-24

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

90 participants

Study Classification

OBSERVATIONAL

Study Start Date

2017-05-02

Study Completion Date

2017-10-08

Brief Summary

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The serum procalcitonin levels are important during infections and sepsis. The investigators aimed to assess its predictive value in terms of post-cesarean wound infection.

Detailed Description

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The serum procalcitonin levels are important during infections and sepsis. Recent studies showed that serum procalcitonin levels are more sensitive than serum CRP levels.The investigators aimed to assess its predictive value in terms of post-cesarean wound infection. The serum procalcitonin levels are aimed to measure in participants who had cesarean section and developed surgical site infection. The investigators aimed to compare the serum procalcitonin levels between the patients who need secondary suture and the patients who did not need secondary suture.

Conditions

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Wound Infection Cesarean Wound Disruption

Study Design

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Observational Model Type

COHORT

Study Time Perspective

CROSS_SECTIONAL

Study Groups

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No secondary suture

The participants who developed post-cesarean surgical site infection and follow-up only antibiotic treatment for their wound care.

procalcitonin level

Intervention Type OTHER

serum procalcitonin level will be measured in both groups.

Secondary suture

The participants who developed post-cesarean surgical site infection and need a secondary suture for their wound care

procalcitonin level

Intervention Type OTHER

serum procalcitonin level will be measured in both groups.

Interventions

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procalcitonin level

serum procalcitonin level will be measured in both groups.

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* who developed surgical site infection after their cesarean sections.
* 18-40 years old

Exclusion Criteria

* history of chorioamnionitis and premature rupture of membranes
* urinary tract infections
* any infectious condition other than surgical site infection
Minimum Eligible Age

18 Years

Maximum Eligible Age

40 Years

Eligible Sex

FEMALE

Accepts Healthy Volunteers

No

Sponsors

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Kanuni Sultan Suleyman Training and Research Hospital

OTHER

Sponsor Role lead

Responsible Party

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Berna Aslan Cetin

MD,ObGYN

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Alev Atis, MD,ObGyn

Role: STUDY_DIRECTOR

Kanuni Sultan Suleyman Training and Research Hospital

Locations

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Kanuni SSRTH

Istanbul, , Turkey (Türkiye)

Site Status

Countries

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Turkey (Türkiye)

References

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Wacker C, Prkno A, Brunkhorst FM, Schlattmann P. Procalcitonin as a diagnostic marker for sepsis: a systematic review and meta-analysis. Lancet Infect Dis. 2013 May;13(5):426-35. doi: 10.1016/S1473-3099(12)70323-7. Epub 2013 Feb 1.

Reference Type BACKGROUND
PMID: 23375419 (View on PubMed)

Takakura Y, Hinoi T, Egi H, Shimomura M, Adachi T, Saito Y, Tanimine N, Miguchi M, Ohdan H. Procalcitonin as a predictive marker for surgical site infection in elective colorectal cancer surgery. Langenbecks Arch Surg. 2013 Aug;398(6):833-9. doi: 10.1007/s00423-013-1095-0. Epub 2013 Jun 20.

Reference Type BACKGROUND
PMID: 23784676 (View on PubMed)

Erenel H, Yilmaz N, Oncul M, Acikgoz AS, Karatas S, Ayhan I, Aslan B, Tuten A. Usefulness of Serum Procalcitonin Levels in Predicting Tubo-Ovarian Abscess in Patients with Acute Pelvic Inflammatory Disease. Gynecol Obstet Invest. 2017;82(3):262-266. doi: 10.1159/000449161. Epub 2016 Sep 3.

Reference Type RESULT
PMID: 27592364 (View on PubMed)

Aslan Cetin B, Aydogan Mathyk B, Koroglu N, Temel Yuksel I, Konal M, Erenel H, Atis Aydin A. Serum procalcitonin levels in incisional surgical site infections requiring a secondary suture after cesarean sections. J Matern Fetal Neonatal Med. 2019 Dec;32(24):4108-4113. doi: 10.1080/14767058.2018.1481949. Epub 2018 Jun 20.

Reference Type DERIVED
PMID: 29804483 (View on PubMed)

Other Identifiers

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2016/12.2

Identifier Type: -

Identifier Source: org_study_id