Immediate Versus Delayed FET Following a Stimulated IVF Cycle

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

724 participants

Study Classification

INTERVENTIONAL

Study Start Date

2017-08-09

Study Completion Date

2019-12-31

Brief Summary

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Information regarding the optimal timing for frozen-thawed embryo transfer (FET) following a stimulated in vitro fertilization (IVF) is lacking. One option is to perform FET in the first cycle following the stimulated IVF cycle, i.e. immediate transfer. Another option is to postpone FET for at least one menstrual cycle, i.e. delayed transfer. This randomized study aims to compare the ongoing pregnancy rate of immediate versus delayed FET following a stimulated IVF cycle.

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Detailed Description

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Conditions

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Fertilization in Vitro Embryo Transfer

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

No masking because of the nature of the intervention

Study Groups

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immediate group

the intervention: immediate frozen-thawed embryo transfer (FET) which means FET will be performed in the first cycle following the stimulated IVF cycle

Group Type OTHER

immediate frozen-thawed embryo transfer

Intervention Type OTHER

Frozen-thawed embryo transfer will be performed in the first cycle following the stimulated IVF cycle

delayed group

the intervention: delayed frozen-thawed embryo transfer (FET) which means FET will be performed at least in the second cycle following the stimulated IVF cycle

Group Type OTHER

delayed frozen-thawed embryo transfer

Intervention Type OTHER

Frozen-thawed embryo transfer will be performed at least in the second cycle following the stimulated IVF cycle

Interventions

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immediate frozen-thawed embryo transfer

Frozen-thawed embryo transfer will be performed in the first cycle following the stimulated IVF cycle

Intervention Type OTHER

delayed frozen-thawed embryo transfer

Frozen-thawed embryo transfer will be performed at least in the second cycle following the stimulated IVF cycle

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Women aged ≤43 years at the time of IVF/ICSI treatment Undergoing IVF with a standard stimulation At least one frozen embryo or blastocyst The first FET cycle following ovarian stimulation in IVF/ICSI

Exclusion Criteria

* Use of mild stimulation or natural cycle for IVF/ICSI treatment Severe ovarian hyperstimulation syndrome during IVF/ICSI treatment Preimplantation genetic diagnosis treatment Use of donor oocytes Presence of hydrosalpinx which is not surgically treated or endometrial polyp on scanning during ovarian stimulation

Minimum Eligible Age

20 Years

Maximum Eligible Age

43 Years

Eligible Sex

FEMALE

Accepts Healthy Volunteers

No