Trial Outcomes & Findings for Comparing Interventions to Increase Colorectal Cancer Screening (NCT NCT03200366)

NCT ID: NCT03200366

Last Updated: 2021-09-13

Results Overview

Number of participants completing CRC screening by any test (defined as colonoscopy or FIT) is measured by electronic medical record review. Dates that participants had a colonoscopy and dates of FIT analysis are extracted from the electronic medical record.

• Recruitment status: COMPLETED
• Study phase: NA
• Target enrollment: 371 participants
• Primary outcome timeframe: 12 months post-baseline interview
• Results posted on: 2021-09-13

Participant Flow

Participants were 371 primary care patients from Eskenazi Health clinics located ln Indianapolis, Indiana. Participants were recruited between July 2017 to November 2019. Participants were enrolled after providing informed consent and HIPAA authorization to obtain CRC screening information from their electronic medical record (EMR). EMR was reviewed for completion of CRC screening by colonoscopy and FIT for ALL participants, regardless of whether or not post-baseline interviews were completed.

Participant milestones

Measure	Tailored DVD Tailored digital video disc (DVD) DVD: A 20 minute tailored DVD titled "Approaches to Colon Testing" is viewed by participants. It is designed to encourage CRC screening uptake by colonoscopy or FIT by increasing the participant's CRC knowledge and beliefs about the benefits of screening, reducing barriers to screening, and increasing self-efficacy for screening by demonstrating how these tests are performed.	Tailored DVD + Patient Navigation Tailored digital video disc (DVD) plus Patient Navigation by a population health nurse in the healthcare system DVD: A 20 minute tailored DVD titled "Approaches to Colon Testing" is viewed by participants. It is designed to encourage CRC screening uptake by colonoscopy or FIT by increasing the participant's CRC knowledge and beliefs about the benefits of screening, reducing barriers to screening, and increasing self-efficacy for screening by demonstrating how these tests are performed. Patient Navigation: Participants talk by telephone with a Patient Navigator who is a trained nurse. The Patient Navigator determines if participants viewed the tailored DVD and answers any questions about the content. The Patient Navigator then provides telephone counseling on CRC and screening tests to: (1) increase knowledge, perceived benefits, and self-efficacy; (2) reduce barriers; (3) enhance access; and (4) provide social support.	Usual Care Care normally provided by a nurse in the endoscopy department of the healthcare system
Baseline Interview With Randomization STARTED	123	120	128
Baseline Interview With Randomization COMPLETED	123	120	128
Baseline Interview With Randomization NOT COMPLETED	0	0	0
Tailored DVD Intervention Given STARTED	123	120	0
Tailored DVD Intervention Given COMPLETED	123	120	0
Tailored DVD Intervention Given NOT COMPLETED	0	0	0
Patient Navigation Intervention Given STARTED	0	120	0
Patient Navigation Intervention Given COMPLETED	0	89	0
Patient Navigation Intervention Given NOT COMPLETED	0	31	0
6 Month Post-Baseline Interview STARTED	123	118	128
6 Month Post-Baseline Interview COMPLETED	93	95	109
6 Month Post-Baseline Interview NOT COMPLETED	30	23	19
9 Month Post-Baseline Interview STARTED	121	116	127
9 Month Post-Baseline Interview COMPLETED	97	95	116
9 Month Post-Baseline Interview NOT COMPLETED	24	21	11

Reasons for withdrawal

Measure	Tailored DVD Tailored digital video disc (DVD) DVD: A 20 minute tailored DVD titled "Approaches to Colon Testing" is viewed by participants. It is designed to encourage CRC screening uptake by colonoscopy or FIT by increasing the participant's CRC knowledge and beliefs about the benefits of screening, reducing barriers to screening, and increasing self-efficacy for screening by demonstrating how these tests are performed.	Tailored DVD + Patient Navigation Tailored digital video disc (DVD) plus Patient Navigation by a population health nurse in the healthcare system DVD: A 20 minute tailored DVD titled "Approaches to Colon Testing" is viewed by participants. It is designed to encourage CRC screening uptake by colonoscopy or FIT by increasing the participant's CRC knowledge and beliefs about the benefits of screening, reducing barriers to screening, and increasing self-efficacy for screening by demonstrating how these tests are performed. Patient Navigation: Participants talk by telephone with a Patient Navigator who is a trained nurse. The Patient Navigator determines if participants viewed the tailored DVD and answers any questions about the content. The Patient Navigator then provides telephone counseling on CRC and screening tests to: (1) increase knowledge, perceived benefits, and self-efficacy; (2) reduce barriers; (3) enhance access; and (4) provide social support.	Usual Care Care normally provided by a nurse in the endoscopy department of the healthcare system
Patient Navigation Intervention Given Death	0	2	0
Patient Navigation Intervention Given Lost to Follow-up	0	25	0
Patient Navigation Intervention Given Not attempted/missed by nurse	0	1	0
Patient Navigation Intervention Given Colonoscopy already re-scheduled and completed	0	2	0
Patient Navigation Intervention Given Declined navigation intervention	0	1	0
6 Month Post-Baseline Interview Death	1	1	1
6 Month Post-Baseline Interview Lost to Follow-up	27	21	17
6 Month Post-Baseline Interview Withdrawal by Subject	1	1	0
6 Month Post-Baseline Interview Refused 6 month interview but continued in study	1	0	0
6 Month Post-Baseline Interview Not attempted/missed by data collectors	0	0	1
9 Month Post-Baseline Interview Death	1	1	1
9 Month Post-Baseline Interview Lost to Follow-up	23	18	9
9 Month Post-Baseline Interview Withdrawal by PI	0	0	1
9 Month Post-Baseline Interview Refused interview	0	2	0

Baseline Characteristics

Enrolled participants who completed the baseline interview. Excludes 1 participant from the Tailored DVD + Patient Navigation group whose data were missing.

Baseline characteristics by cohort

Measure	Tailored DVD n=123 Participants Tailored digital video disc (DVD) DVD: A 20 minute tailored DVD titled "Approaches to Colon Testing" is viewed by participants. It is designed to encourage CRC screening uptake by colonoscopy or FIT by increasing the participant's CRC knowledge and beliefs about the benefits of screening, reducing barriers to screening, and increasing self-efficacy for screening by demonstrating how these tests are performed.	Tailored DVD + Patient Navigation n=120 Participants Tailored digital video disc (DVD) plus Patient Navigation by a population health nurse in the healthcare system DVD: A 20 minute tailored DVD titled "Approaches to Colon Testing" is viewed by participants. It is designed to encourage CRC screening uptake by colonoscopy or FIT by increasing the participant's CRC knowledge and beliefs about the benefits of screening, reducing barriers to screening, and increasing self-efficacy for screening by demonstrating how these tests are performed. Patient Navigation: Participants talk by telephone with a Patient Navigator who is a trained nurse. The Patient Navigator determines if participants viewed the tailored DVD and answers any questions about the content. The Patient Navigator then provides telephone counseling on CRC and screening tests to: (1) increase knowledge, perceived benefits, and self-efficacy; (2) reduce barriers; (3) enhance access; and (4) provide social support.	Usual Care n=128 Participants Care normally provided by a nurse in the endoscopy department of the healthcare system	Total n=371 Participants Total of all reporting groups
Age, Continuous	58.20 years STANDARD_DEVIATION 6.07 • n=123 Participants	57.29 years STANDARD_DEVIATION 5.63 • n=120 Participants	57.83 years STANDARD_DEVIATION 6.17 • n=128 Participants	57.78 years STANDARD_DEVIATION 5.96 • n=371 Participants
Sex: Female, Male Female	75 Participants n=123 Participants	73 Participants n=120 Participants	77 Participants n=128 Participants	225 Participants n=371 Participants
Sex: Female, Male Male	48 Participants n=123 Participants	47 Participants n=120 Participants	51 Participants n=128 Participants	146 Participants n=371 Participants
Race/Ethnicity, Customized Non-Hispanic Whte	35 Participants n=123 Participants	33 Participants n=120 Participants	36 Participants n=128 Participants	104 Participants n=371 Participants
Race/Ethnicity, Customized Non-Hispanic Non-White	83 Participants n=123 Participants	82 Participants n=120 Participants	87 Participants n=128 Participants	252 Participants n=371 Participants
Race/Ethnicity, Customized Other	5 Participants n=123 Participants	5 Participants n=120 Participants	5 Participants n=128 Participants	15 Participants n=371 Participants
Region of Enrollment United States	123 participants n=123 Participants	120 participants n=120 Participants	128 participants n=128 Participants	371 participants n=371 Participants
Married/Partnered	38 Participants n=123 Participants • Enrolled participants who completed the baseline interview. Excludes 1 participant from the Tailored DVD + Patient Navigation group whose data were missing.	36 Participants n=119 Participants • Enrolled participants who completed the baseline interview. Excludes 1 participant from the Tailored DVD + Patient Navigation group whose data were missing.	40 Participants n=128 Participants • Enrolled participants who completed the baseline interview. Excludes 1 participant from the Tailored DVD + Patient Navigation group whose data were missing.	114 Participants n=370 Participants • Enrolled participants who completed the baseline interview. Excludes 1 participant from the Tailored DVD + Patient Navigation group whose data were missing.
Education No school through 11th grade	28 Participants n=123 Participants • Enrolled participants who completed the baseline interview. Excludes 1 participant in Usual Care group whose data were missing.	22 Participants n=120 Participants • Enrolled participants who completed the baseline interview. Excludes 1 participant in Usual Care group whose data were missing.	35 Participants n=127 Participants • Enrolled participants who completed the baseline interview. Excludes 1 participant in Usual Care group whose data were missing.	85 Participants n=370 Participants • Enrolled participants who completed the baseline interview. Excludes 1 participant in Usual Care group whose data were missing.
Education 12th grade, high school, diploma, or GED	42 Participants n=123 Participants • Enrolled participants who completed the baseline interview. Excludes 1 participant in Usual Care group whose data were missing.	41 Participants n=120 Participants • Enrolled participants who completed the baseline interview. Excludes 1 participant in Usual Care group whose data were missing.	46 Participants n=127 Participants • Enrolled participants who completed the baseline interview. Excludes 1 participant in Usual Care group whose data were missing.	129 Participants n=370 Participants • Enrolled participants who completed the baseline interview. Excludes 1 participant in Usual Care group whose data were missing.
Education Vocational school or 1-3 years college	39 Participants n=123 Participants • Enrolled participants who completed the baseline interview. Excludes 1 participant in Usual Care group whose data were missing.	45 Participants n=120 Participants • Enrolled participants who completed the baseline interview. Excludes 1 participant in Usual Care group whose data were missing.	34 Participants n=127 Participants • Enrolled participants who completed the baseline interview. Excludes 1 participant in Usual Care group whose data were missing.	118 Participants n=370 Participants • Enrolled participants who completed the baseline interview. Excludes 1 participant in Usual Care group whose data were missing.
Education 4 year college graduate, some graduate work, or completed graduate degree	14 Participants n=123 Participants • Enrolled participants who completed the baseline interview. Excludes 1 participant in Usual Care group whose data were missing.	12 Participants n=120 Participants • Enrolled participants who completed the baseline interview. Excludes 1 participant in Usual Care group whose data were missing.	12 Participants n=127 Participants • Enrolled participants who completed the baseline interview. Excludes 1 participant in Usual Care group whose data were missing.	38 Participants n=370 Participants • Enrolled participants who completed the baseline interview. Excludes 1 participant in Usual Care group whose data were missing.
Number in Household 1 person	47 Participants n=121 Participants • Enrolled participants who completed the baseline interview. Excludes 2 participants in the Tailored DVD group whose data were missing. Excludes 3 participants in the Tailored DVD + Patient Navigation group whose data were missing. Excludes 2 participants in the Usual Care group whose data were missing.	39 Participants n=117 Participants • Enrolled participants who completed the baseline interview. Excludes 2 participants in the Tailored DVD group whose data were missing. Excludes 3 participants in the Tailored DVD + Patient Navigation group whose data were missing. Excludes 2 participants in the Usual Care group whose data were missing.	52 Participants n=126 Participants • Enrolled participants who completed the baseline interview. Excludes 2 participants in the Tailored DVD group whose data were missing. Excludes 3 participants in the Tailored DVD + Patient Navigation group whose data were missing. Excludes 2 participants in the Usual Care group whose data were missing.	138 Participants n=364 Participants • Enrolled participants who completed the baseline interview. Excludes 2 participants in the Tailored DVD group whose data were missing. Excludes 3 participants in the Tailored DVD + Patient Navigation group whose data were missing. Excludes 2 participants in the Usual Care group whose data were missing.
Number in Household 2 persons	46 Participants n=121 Participants • Enrolled participants who completed the baseline interview. Excludes 2 participants in the Tailored DVD group whose data were missing. Excludes 3 participants in the Tailored DVD + Patient Navigation group whose data were missing. Excludes 2 participants in the Usual Care group whose data were missing.	44 Participants n=117 Participants • Enrolled participants who completed the baseline interview. Excludes 2 participants in the Tailored DVD group whose data were missing. Excludes 3 participants in the Tailored DVD + Patient Navigation group whose data were missing. Excludes 2 participants in the Usual Care group whose data were missing.	33 Participants n=126 Participants • Enrolled participants who completed the baseline interview. Excludes 2 participants in the Tailored DVD group whose data were missing. Excludes 3 participants in the Tailored DVD + Patient Navigation group whose data were missing. Excludes 2 participants in the Usual Care group whose data were missing.	123 Participants n=364 Participants • Enrolled participants who completed the baseline interview. Excludes 2 participants in the Tailored DVD group whose data were missing. Excludes 3 participants in the Tailored DVD + Patient Navigation group whose data were missing. Excludes 2 participants in the Usual Care group whose data were missing.
Number in Household 3 or more persons	28 Participants n=121 Participants • Enrolled participants who completed the baseline interview. Excludes 2 participants in the Tailored DVD group whose data were missing. Excludes 3 participants in the Tailored DVD + Patient Navigation group whose data were missing. Excludes 2 participants in the Usual Care group whose data were missing.	34 Participants n=117 Participants • Enrolled participants who completed the baseline interview. Excludes 2 participants in the Tailored DVD group whose data were missing. Excludes 3 participants in the Tailored DVD + Patient Navigation group whose data were missing. Excludes 2 participants in the Usual Care group whose data were missing.	41 Participants n=126 Participants • Enrolled participants who completed the baseline interview. Excludes 2 participants in the Tailored DVD group whose data were missing. Excludes 3 participants in the Tailored DVD + Patient Navigation group whose data were missing. Excludes 2 participants in the Usual Care group whose data were missing.	103 Participants n=364 Participants • Enrolled participants who completed the baseline interview. Excludes 2 participants in the Tailored DVD group whose data were missing. Excludes 3 participants in the Tailored DVD + Patient Navigation group whose data were missing. Excludes 2 participants in the Usual Care group whose data were missing.
Children Under Age 18 in Household	20 Participants n=123 Participants • Enrolled participants who completed the baseline interview. Excludes 1 participant in the Tailored DVD + Patient Navigation group whose data were missing. Excludes 1 participant in the Usual Care group whose data were missing.	25 Participants n=119 Participants • Enrolled participants who completed the baseline interview. Excludes 1 participant in the Tailored DVD + Patient Navigation group whose data were missing. Excludes 1 participant in the Usual Care group whose data were missing.	33 Participants n=127 Participants • Enrolled participants who completed the baseline interview. Excludes 1 participant in the Tailored DVD + Patient Navigation group whose data were missing. Excludes 1 participant in the Usual Care group whose data were missing.	78 Participants n=369 Participants • Enrolled participants who completed the baseline interview. Excludes 1 participant in the Tailored DVD + Patient Navigation group whose data were missing. Excludes 1 participant in the Usual Care group whose data were missing.
Employment Status Not employed	83 Participants n=123 Participants • Enrolled participants who completed the baseline interview. Excludes 1 participant in the Usual Care group whose data were missing.	66 Participants n=120 Participants • Enrolled participants who completed the baseline interview. Excludes 1 participant in the Usual Care group whose data were missing.	87 Participants n=127 Participants • Enrolled participants who completed the baseline interview. Excludes 1 participant in the Usual Care group whose data were missing.	236 Participants n=370 Participants • Enrolled participants who completed the baseline interview. Excludes 1 participant in the Usual Care group whose data were missing.
Employment Status Part-time	18 Participants n=123 Participants • Enrolled participants who completed the baseline interview. Excludes 1 participant in the Usual Care group whose data were missing.	19 Participants n=120 Participants • Enrolled participants who completed the baseline interview. Excludes 1 participant in the Usual Care group whose data were missing.	16 Participants n=127 Participants • Enrolled participants who completed the baseline interview. Excludes 1 participant in the Usual Care group whose data were missing.	53 Participants n=370 Participants • Enrolled participants who completed the baseline interview. Excludes 1 participant in the Usual Care group whose data were missing.
Employment Status Full-time	22 Participants n=123 Participants • Enrolled participants who completed the baseline interview. Excludes 1 participant in the Usual Care group whose data were missing.	35 Participants n=120 Participants • Enrolled participants who completed the baseline interview. Excludes 1 participant in the Usual Care group whose data were missing.	24 Participants n=127 Participants • Enrolled participants who completed the baseline interview. Excludes 1 participant in the Usual Care group whose data were missing.	81 Participants n=370 Participants • Enrolled participants who completed the baseline interview. Excludes 1 participant in the Usual Care group whose data were missing.
Household Income Less than $15,000	57 Participants n=121 Participants • Enrolled participants who completed the baseline interview. Excludes 2 participants in the Tailored DVD group whose data were missing. Excludes 6 participants in the Tailored DVD + Patient Navigation group whose data were missing. Excludes 5 participants in the Usual Care group whose data were missing.	45 Participants n=114 Participants • Enrolled participants who completed the baseline interview. Excludes 2 participants in the Tailored DVD group whose data were missing. Excludes 6 participants in the Tailored DVD + Patient Navigation group whose data were missing. Excludes 5 participants in the Usual Care group whose data were missing.	52 Participants n=123 Participants • Enrolled participants who completed the baseline interview. Excludes 2 participants in the Tailored DVD group whose data were missing. Excludes 6 participants in the Tailored DVD + Patient Navigation group whose data were missing. Excludes 5 participants in the Usual Care group whose data were missing.	154 Participants n=358 Participants • Enrolled participants who completed the baseline interview. Excludes 2 participants in the Tailored DVD group whose data were missing. Excludes 6 participants in the Tailored DVD + Patient Navigation group whose data were missing. Excludes 5 participants in the Usual Care group whose data were missing.
Household Income $15,001-$30,000	46 Participants n=121 Participants • Enrolled participants who completed the baseline interview. Excludes 2 participants in the Tailored DVD group whose data were missing. Excludes 6 participants in the Tailored DVD + Patient Navigation group whose data were missing. Excludes 5 participants in the Usual Care group whose data were missing.	40 Participants n=114 Participants • Enrolled participants who completed the baseline interview. Excludes 2 participants in the Tailored DVD group whose data were missing. Excludes 6 participants in the Tailored DVD + Patient Navigation group whose data were missing. Excludes 5 participants in the Usual Care group whose data were missing.	44 Participants n=123 Participants • Enrolled participants who completed the baseline interview. Excludes 2 participants in the Tailored DVD group whose data were missing. Excludes 6 participants in the Tailored DVD + Patient Navigation group whose data were missing. Excludes 5 participants in the Usual Care group whose data were missing.	130 Participants n=358 Participants • Enrolled participants who completed the baseline interview. Excludes 2 participants in the Tailored DVD group whose data were missing. Excludes 6 participants in the Tailored DVD + Patient Navigation group whose data were missing. Excludes 5 participants in the Usual Care group whose data were missing.
Household Income $30,001-$50,000	13 Participants n=121 Participants • Enrolled participants who completed the baseline interview. Excludes 2 participants in the Tailored DVD group whose data were missing. Excludes 6 participants in the Tailored DVD + Patient Navigation group whose data were missing. Excludes 5 participants in the Usual Care group whose data were missing.	20 Participants n=114 Participants • Enrolled participants who completed the baseline interview. Excludes 2 participants in the Tailored DVD group whose data were missing. Excludes 6 participants in the Tailored DVD + Patient Navigation group whose data were missing. Excludes 5 participants in the Usual Care group whose data were missing.	15 Participants n=123 Participants • Enrolled participants who completed the baseline interview. Excludes 2 participants in the Tailored DVD group whose data were missing. Excludes 6 participants in the Tailored DVD + Patient Navigation group whose data were missing. Excludes 5 participants in the Usual Care group whose data were missing.	48 Participants n=358 Participants • Enrolled participants who completed the baseline interview. Excludes 2 participants in the Tailored DVD group whose data were missing. Excludes 6 participants in the Tailored DVD + Patient Navigation group whose data were missing. Excludes 5 participants in the Usual Care group whose data were missing.
Household Income $50,001 to more than $100,000	5 Participants n=121 Participants • Enrolled participants who completed the baseline interview. Excludes 2 participants in the Tailored DVD group whose data were missing. Excludes 6 participants in the Tailored DVD + Patient Navigation group whose data were missing. Excludes 5 participants in the Usual Care group whose data were missing.	9 Participants n=114 Participants • Enrolled participants who completed the baseline interview. Excludes 2 participants in the Tailored DVD group whose data were missing. Excludes 6 participants in the Tailored DVD + Patient Navigation group whose data were missing. Excludes 5 participants in the Usual Care group whose data were missing.	12 Participants n=123 Participants • Enrolled participants who completed the baseline interview. Excludes 2 participants in the Tailored DVD group whose data were missing. Excludes 6 participants in the Tailored DVD + Patient Navigation group whose data were missing. Excludes 5 participants in the Usual Care group whose data were missing.	26 Participants n=358 Participants • Enrolled participants who completed the baseline interview. Excludes 2 participants in the Tailored DVD group whose data were missing. Excludes 6 participants in the Tailored DVD + Patient Navigation group whose data were missing. Excludes 5 participants in the Usual Care group whose data were missing.
Household Income Categorized by $15K Level Less than $15,000	57 Participants n=121 Participants • Enrolled participants who completed the baseline interview. Excludes 2 participants in the Tailored DVD group whose data were missing. Excludes 6 participants in the Tailored DVD + Patient Navigation group whose data were missing. Excludes 5 participants in the Usual Care group whose data were missing.	45 Participants n=114 Participants • Enrolled participants who completed the baseline interview. Excludes 2 participants in the Tailored DVD group whose data were missing. Excludes 6 participants in the Tailored DVD + Patient Navigation group whose data were missing. Excludes 5 participants in the Usual Care group whose data were missing.	52 Participants n=123 Participants • Enrolled participants who completed the baseline interview. Excludes 2 participants in the Tailored DVD group whose data were missing. Excludes 6 participants in the Tailored DVD + Patient Navigation group whose data were missing. Excludes 5 participants in the Usual Care group whose data were missing.	154 Participants n=358 Participants • Enrolled participants who completed the baseline interview. Excludes 2 participants in the Tailored DVD group whose data were missing. Excludes 6 participants in the Tailored DVD + Patient Navigation group whose data were missing. Excludes 5 participants in the Usual Care group whose data were missing.
Household Income Categorized by $15K Level $15,000 or more	64 Participants n=121 Participants • Enrolled participants who completed the baseline interview. Excludes 2 participants in the Tailored DVD group whose data were missing. Excludes 6 participants in the Tailored DVD + Patient Navigation group whose data were missing. Excludes 5 participants in the Usual Care group whose data were missing.	69 Participants n=114 Participants • Enrolled participants who completed the baseline interview. Excludes 2 participants in the Tailored DVD group whose data were missing. Excludes 6 participants in the Tailored DVD + Patient Navigation group whose data were missing. Excludes 5 participants in the Usual Care group whose data were missing.	71 Participants n=123 Participants • Enrolled participants who completed the baseline interview. Excludes 2 participants in the Tailored DVD group whose data were missing. Excludes 6 participants in the Tailored DVD + Patient Navigation group whose data were missing. Excludes 5 participants in the Usual Care group whose data were missing.	204 Participants n=358 Participants • Enrolled participants who completed the baseline interview. Excludes 2 participants in the Tailored DVD group whose data were missing. Excludes 6 participants in the Tailored DVD + Patient Navigation group whose data were missing. Excludes 5 participants in the Usual Care group whose data were missing.
Adequacy of Income After paying the bills, there is enough money for special things that the participant wants.	17 Participants n=119 Participants • Enrolled participants who completed the baseline interview. Excludes 4 participants in the Tailored DVD group whose data were missing. Excludes 7 participants in the Tailored DVD + Patient Navigation group whose data were missing. Excludes 6 participants in the Usual Care group whose data were missing.	16 Participants n=113 Participants • Enrolled participants who completed the baseline interview. Excludes 4 participants in the Tailored DVD group whose data were missing. Excludes 7 participants in the Tailored DVD + Patient Navigation group whose data were missing. Excludes 6 participants in the Usual Care group whose data were missing.	20 Participants n=122 Participants • Enrolled participants who completed the baseline interview. Excludes 4 participants in the Tailored DVD group whose data were missing. Excludes 7 participants in the Tailored DVD + Patient Navigation group whose data were missing. Excludes 6 participants in the Usual Care group whose data were missing.	53 Participants n=354 Participants • Enrolled participants who completed the baseline interview. Excludes 4 participants in the Tailored DVD group whose data were missing. Excludes 7 participants in the Tailored DVD + Patient Navigation group whose data were missing. Excludes 6 participants in the Usual Care group whose data were missing.
Adequacy of Income There is enough money to pay the bills, but little spare money to buy extra or special things.	44 Participants n=119 Participants • Enrolled participants who completed the baseline interview. Excludes 4 participants in the Tailored DVD group whose data were missing. Excludes 7 participants in the Tailored DVD + Patient Navigation group whose data were missing. Excludes 6 participants in the Usual Care group whose data were missing.	41 Participants n=113 Participants • Enrolled participants who completed the baseline interview. Excludes 4 participants in the Tailored DVD group whose data were missing. Excludes 7 participants in the Tailored DVD + Patient Navigation group whose data were missing. Excludes 6 participants in the Usual Care group whose data were missing.	44 Participants n=122 Participants • Enrolled participants who completed the baseline interview. Excludes 4 participants in the Tailored DVD group whose data were missing. Excludes 7 participants in the Tailored DVD + Patient Navigation group whose data were missing. Excludes 6 participants in the Usual Care group whose data were missing.	129 Participants n=354 Participants • Enrolled participants who completed the baseline interview. Excludes 4 participants in the Tailored DVD group whose data were missing. Excludes 7 participants in the Tailored DVD + Patient Navigation group whose data were missing. Excludes 6 participants in the Usual Care group whose data were missing.
Adequacy of Income There is enough money to pay the bills, but only because the participant cuts back on things.	22 Participants n=119 Participants • Enrolled participants who completed the baseline interview. Excludes 4 participants in the Tailored DVD group whose data were missing. Excludes 7 participants in the Tailored DVD + Patient Navigation group whose data were missing. Excludes 6 participants in the Usual Care group whose data were missing.	22 Participants n=113 Participants • Enrolled participants who completed the baseline interview. Excludes 4 participants in the Tailored DVD group whose data were missing. Excludes 7 participants in the Tailored DVD + Patient Navigation group whose data were missing. Excludes 6 participants in the Usual Care group whose data were missing.	21 Participants n=122 Participants • Enrolled participants who completed the baseline interview. Excludes 4 participants in the Tailored DVD group whose data were missing. Excludes 7 participants in the Tailored DVD + Patient Navigation group whose data were missing. Excludes 6 participants in the Usual Care group whose data were missing.	65 Participants n=354 Participants • Enrolled participants who completed the baseline interview. Excludes 4 participants in the Tailored DVD group whose data were missing. Excludes 7 participants in the Tailored DVD + Patient Navigation group whose data were missing. Excludes 6 participants in the Usual Care group whose data were missing.
Adequacy of Income The participant has difficulty paying the bills, no matter what is done.	36 Participants n=119 Participants • Enrolled participants who completed the baseline interview. Excludes 4 participants in the Tailored DVD group whose data were missing. Excludes 7 participants in the Tailored DVD + Patient Navigation group whose data were missing. Excludes 6 participants in the Usual Care group whose data were missing.	34 Participants n=113 Participants • Enrolled participants who completed the baseline interview. Excludes 4 participants in the Tailored DVD group whose data were missing. Excludes 7 participants in the Tailored DVD + Patient Navigation group whose data were missing. Excludes 6 participants in the Usual Care group whose data were missing.	37 Participants n=122 Participants • Enrolled participants who completed the baseline interview. Excludes 4 participants in the Tailored DVD group whose data were missing. Excludes 7 participants in the Tailored DVD + Patient Navigation group whose data were missing. Excludes 6 participants in the Usual Care group whose data were missing.	107 Participants n=354 Participants • Enrolled participants who completed the baseline interview. Excludes 4 participants in the Tailored DVD group whose data were missing. Excludes 7 participants in the Tailored DVD + Patient Navigation group whose data were missing. Excludes 6 participants in the Usual Care group whose data were missing.
Health Insurance Coverage	114 Participants n=123 Participants • Enrolled participants who completed the baseline interview. Excludes 1 participant in the Usual Care group whose data were missing.	114 Participants n=120 Participants • Enrolled participants who completed the baseline interview. Excludes 1 participant in the Usual Care group whose data were missing.	121 Participants n=127 Participants • Enrolled participants who completed the baseline interview. Excludes 1 participant in the Usual Care group whose data were missing.	349 Participants n=370 Participants • Enrolled participants who completed the baseline interview. Excludes 1 participant in the Usual Care group whose data were missing.
Body Mass Index (BMI)	31.57 kg/m^2 STANDARD_DEVIATION 8.89 • n=123 Participants • Enrolled participants who completed the baseline interview. Excludes 3 participants in the Tailored DVD + Patient Navigation group whose data were missing.	30.18 kg/m^2 STANDARD_DEVIATION 7.86 • n=117 Participants • Enrolled participants who completed the baseline interview. Excludes 3 participants in the Tailored DVD + Patient Navigation group whose data were missing.	31.50 kg/m^2 STANDARD_DEVIATION 8.93 • n=128 Participants • Enrolled participants who completed the baseline interview. Excludes 3 participants in the Tailored DVD + Patient Navigation group whose data were missing.	31.10 kg/m^2 STANDARD_DEVIATION 8.59 • n=368 Participants • Enrolled participants who completed the baseline interview. Excludes 3 participants in the Tailored DVD + Patient Navigation group whose data were missing.
Global Physical Health	12.64 units on a scale STANDARD_DEVIATION 3.24 • n=123 Participants • Enrolled participants who completed the baseline interview. Excludes 1 participant in the Tailored DVD + Patient Navigation group whose data were missing. Excludes 3 participants in the Usual Care group whose data were missing.	13.37 units on a scale STANDARD_DEVIATION 3.29 • n=119 Participants • Enrolled participants who completed the baseline interview. Excludes 1 participant in the Tailored DVD + Patient Navigation group whose data were missing. Excludes 3 participants in the Usual Care group whose data were missing.	12.89 units on a scale STANDARD_DEVIATION 3.38 • n=125 Participants • Enrolled participants who completed the baseline interview. Excludes 1 participant in the Tailored DVD + Patient Navigation group whose data were missing. Excludes 3 participants in the Usual Care group whose data were missing.	12.96 units on a scale STANDARD_DEVIATION 3.31 • n=367 Participants • Enrolled participants who completed the baseline interview. Excludes 1 participant in the Tailored DVD + Patient Navigation group whose data were missing. Excludes 3 participants in the Usual Care group whose data were missing.
Global Mental Health	12.86 units on a scale STANDARD_DEVIATION 3.19 • n=123 Participants • Enrolled participants who completed the baseline interview. Excludes 2 participants in the Tailored DVD + Patient Navigation group whose data were missing.	12.73 units on a scale STANDARD_DEVIATION 3.50 • n=118 Participants • Enrolled participants who completed the baseline interview. Excludes 2 participants in the Tailored DVD + Patient Navigation group whose data were missing.	12.88 units on a scale STANDARD_DEVIATION 3.31 • n=128 Participants • Enrolled participants who completed the baseline interview. Excludes 2 participants in the Tailored DVD + Patient Navigation group whose data were missing.	12.82 units on a scale STANDARD_DEVIATION 3.32 • n=369 Participants • Enrolled participants who completed the baseline interview. Excludes 2 participants in the Tailored DVD + Patient Navigation group whose data were missing.
Health Literacy	12.20 units on a scale STANDARD_DEVIATION 2.74 • n=123 Participants • Enrolled participants who completed the baseline interview. Excludes 1 participant in the Tailored DVD + Patient Navigation group whose data were missing.	11.97 units on a scale STANDARD_DEVIATION 2.64 • n=119 Participants • Enrolled participants who completed the baseline interview. Excludes 1 participant in the Tailored DVD + Patient Navigation group whose data were missing.	11.91 units on a scale STANDARD_DEVIATION 3.18 • n=128 Participants • Enrolled participants who completed the baseline interview. Excludes 1 participant in the Tailored DVD + Patient Navigation group whose data were missing.	12.03 units on a scale STANDARD_DEVIATION 2.87 • n=370 Participants • Enrolled participants who completed the baseline interview. Excludes 1 participant in the Tailored DVD + Patient Navigation group whose data were missing.
Comorbidity	8.24 units on a scale STANDARD_DEVIATION 4.86 • n=123 Participants	7.73 units on a scale STANDARD_DEVIATION 4.83 • n=120 Participants	7.56 units on a scale STANDARD_DEVIATION 4.72 • n=128 Participants	7.84 units on a scale STANDARD_DEVIATION 4.80 • n=371 Participants
Knowledge of CRC and Screening	3.54 units on a scale STANDARD_DEVIATION 1.83 • n=123 Participants	3.62 units on a scale STANDARD_DEVIATION 1.77 • n=120 Participants	2.93 units on a scale STANDARD_DEVIATION 1.72 • n=128 Participants	3.36 units on a scale STANDARD_DEVIATION 1.80 • n=371 Participants
Perceived Risk for CRC	1.97 units on a scale STANDARD_DEVIATION 0.73 • n=114 Participants • Enrolled participants who completed the baseline interview. Excludes 9 participants in the Tailored DVD group whose data were missing. Excludes 2 participants in the Tailored DVD + Patient Navigation group whose data were missing. Excludes 4 participants in the Usual Care group whose data were missing.	1.94 units on a scale STANDARD_DEVIATION 0.80 • n=118 Participants • Enrolled participants who completed the baseline interview. Excludes 9 participants in the Tailored DVD group whose data were missing. Excludes 2 participants in the Tailored DVD + Patient Navigation group whose data were missing. Excludes 4 participants in the Usual Care group whose data were missing.	2.03 units on a scale STANDARD_DEVIATION 0.81 • n=124 Participants • Enrolled participants who completed the baseline interview. Excludes 9 participants in the Tailored DVD group whose data were missing. Excludes 2 participants in the Tailored DVD + Patient Navigation group whose data were missing. Excludes 4 participants in the Usual Care group whose data were missing.	1.98 units on a scale STANDARD_DEVIATION 0.78 • n=356 Participants • Enrolled participants who completed the baseline interview. Excludes 9 participants in the Tailored DVD group whose data were missing. Excludes 2 participants in the Tailored DVD + Patient Navigation group whose data were missing. Excludes 4 participants in the Usual Care group whose data were missing.
Colonoscopy Stage of Adoption Precontemplation	27 Participants n=123 Participants	25 Participants n=120 Participants	29 Participants n=128 Participants	81 Participants n=371 Participants
Colonoscopy Stage of Adoption Contemplation	70 Participants n=123 Participants	67 Participants n=120 Participants	61 Participants n=128 Participants	198 Participants n=371 Participants
Colonoscopy Stage of Adoption Preparation	26 Participants n=123 Participants	28 Participants n=120 Participants	38 Participants n=128 Participants	92 Participants n=371 Participants
Colonoscopy-Related Procedural Anxiety	2.59 units on a scale STANDARD_DEVIATION 0.68 • n=122 Participants • Excludes 1 participant in the Tailored DVD group whose data were missing.	2.60 units on a scale STANDARD_DEVIATION 0.69 • n=120 Participants • Excludes 1 participant in the Tailored DVD group whose data were missing.	2.52 units on a scale STANDARD_DEVIATION 0.59 • n=128 Participants • Excludes 1 participant in the Tailored DVD group whose data were missing.	2.57 units on a scale STANDARD_DEVIATION 0.65 • n=370 Participants • Excludes 1 participant in the Tailored DVD group whose data were missing.
Perceived Benefits of CRC Screening by Colonoscopy	3.22 units on a scale STANDARD_DEVIATION 0.61 • n=121 Participants • Enrolled participants who completed the baseline interview. Excludes 2 participants in the Tailored DVD group whose data was missing. Excludes 1 participant in the Tailored DVD + Patient Navigation group whose data was missing.	3.31 units on a scale STANDARD_DEVIATION 0.57 • n=119 Participants • Enrolled participants who completed the baseline interview. Excludes 2 participants in the Tailored DVD group whose data was missing. Excludes 1 participant in the Tailored DVD + Patient Navigation group whose data was missing.	3.27 units on a scale STANDARD_DEVIATION 0.56 • n=128 Participants • Enrolled participants who completed the baseline interview. Excludes 2 participants in the Tailored DVD group whose data was missing. Excludes 1 participant in the Tailored DVD + Patient Navigation group whose data was missing.	3.27 units on a scale STANDARD_DEVIATION 0.58 • n=368 Participants • Enrolled participants who completed the baseline interview. Excludes 2 participants in the Tailored DVD group whose data was missing. Excludes 1 participant in the Tailored DVD + Patient Navigation group whose data was missing.
Perceived Barriers to CRC Screening by Colonoscopy	2.21 units on a scale STANDARD_DEVIATION 0.56 • n=123 Participants	2.33 units on a scale STANDARD_DEVIATION 0.55 • n=120 Participants	2.29 units on a scale STANDARD_DEVIATION 0.62 • n=128 Participants	2.28 units on a scale STANDARD_DEVIATION 0.58 • n=371 Participants
Perceived Self-Efficacy for CRC Screening by Colonoscopy	3.33 units on a scale STANDARD_DEVIATION 0.56 • n=123 Participants	3.33 units on a scale STANDARD_DEVIATION 0.49 • n=120 Participants	3.36 units on a scale STANDARD_DEVIATION 0.55 • n=128 Participants	3.34 units on a scale STANDARD_DEVIATION 0.53 • n=371 Participants
Fecal Immunochemical Test Stage of Adoption Precontemplation	73 Participants n=123 Participants	80 Participants n=120 Participants	87 Participants n=128 Participants	240 Participants n=371 Participants
Fecal Immunochemical Test Stage of Adoption Contemplation	23 Participants n=123 Participants	20 Participants n=120 Participants	20 Participants n=128 Participants	63 Participants n=371 Participants
Fecal Immunochemical Test Stage of Adoption Preparation	3 Participants n=123 Participants	8 Participants n=120 Participants	6 Participants n=128 Participants	17 Participants n=371 Participants
Fecal Immunochemical Test Stage of Adoption Action	24 Participants n=123 Participants	12 Participants n=120 Participants	15 Participants n=128 Participants	51 Participants n=371 Participants
Perceived Benefits of CRC Screening by FIT	3.06 units on a scale STANDARD_DEVIATION 0.73 • n=117 Participants • Enrolled participants who completed the baseline interview. Excludes 6 participants in the Tailored DVD group whose data were missing. Excludes 3 participants in the Tailored DVD + Patient Navigation group whose data were missing. Excludes 2 participants in the Usual Care group whose data were missing.	3.15 units on a scale STANDARD_DEVIATION 0.64 • n=117 Participants • Enrolled participants who completed the baseline interview. Excludes 6 participants in the Tailored DVD group whose data were missing. Excludes 3 participants in the Tailored DVD + Patient Navigation group whose data were missing. Excludes 2 participants in the Usual Care group whose data were missing.	3.16 units on a scale STANDARD_DEVIATION 0.70 • n=126 Participants • Enrolled participants who completed the baseline interview. Excludes 6 participants in the Tailored DVD group whose data were missing. Excludes 3 participants in the Tailored DVD + Patient Navigation group whose data were missing. Excludes 2 participants in the Usual Care group whose data were missing.	3.13 units on a scale STANDARD_DEVIATION 0.69 • n=360 Participants • Enrolled participants who completed the baseline interview. Excludes 6 participants in the Tailored DVD group whose data were missing. Excludes 3 participants in the Tailored DVD + Patient Navigation group whose data were missing. Excludes 2 participants in the Usual Care group whose data were missing.
Perceived Barriers to CRC Screening by FIT	1.97 units on a scale STANDARD_DEVIATION 0.55 • n=123 Participants	2.20 units on a scale STANDARD_DEVIATION 0.57 • n=120 Participants	2.11 units on a scale STANDARD_DEVIATION 0.62 • n=128 Participants	2.10 units on a scale STANDARD_DEVIATION 0.59 • n=371 Participants
Perceived Self-Efficacy for CRC Screening by FIT	3.63 units on a scale STANDARD_DEVIATION 0.49 • n=123 Participants	3.59 units on a scale STANDARD_DEVIATION 0.48 • n=120 Participants	3.63 units on a scale STANDARD_DEVIATION 0.47 • n=128 Participants	3.61 units on a scale STANDARD_DEVIATION 0.48 • n=371 Participants

PRIMARY outcome

Timeframe: 12 months post-baseline interview

Population: All enrolled participants who completed the baseline interview and were randomized.

Number of participants completing CRC screening by any test (defined as colonoscopy or FIT) is measured by electronic medical record review. Dates that participants had a colonoscopy and dates of FIT analysis are extracted from the electronic medical record.

Outcome measures

Measure	Tailored DVD n=123 Participants Tailored digital video disc (DVD) DVD: A 20 minute tailored DVD titled "Approaches to Colon Testing" is viewed by participants. It is designed to encourage CRC screening uptake by colonoscopy or FIT by increasing the participant's CRC knowledge and beliefs about the benefits of screening, reducing barriers to screening, and increasing self-efficacy for screening by demonstrating how these tests are performed.	Tailored DVD + Patient Navigation n=120 Participants Tailored digital video disc (DVD) plus Patient Navigation by a population health nurse in the healthcare system DVD: A 20 minute tailored DVD titled "Approaches to Colon Testing" is viewed by participants. It is designed to encourage CRC screening uptake by colonoscopy or FIT by increasing the participant's CRC knowledge and beliefs about the benefits of screening, reducing barriers to screening, and increasing self-efficacy for screening by demonstrating how these tests are performed. Patient Navigation: Participants talk by telephone with a Patient Navigator who is a trained nurse. The Patient Navigator determines if participants viewed the tailored DVD and answers any questions about the content. The Patient Navigator then provides telephone counseling on CRC and screening tests to: (1) increase knowledge, perceived benefits, and self-efficacy; (2) reduce barriers; (3) enhance access; and (4) provide social support.	Usual Care n=128 Participants Care normally provided by a nurse in the endoscopy department of the healthcare system
Participants Completing CRC Screening Per Electronic Medical Record Documentation	37 Participants	59 Participants	27 Participants

SECONDARY outcome

Timeframe: 12 months post-baseline interview

Population: All enrolled participants who completed the baseline interview and were randomized.

Number of participants completing a colonoscopy is measured by electronic medical record review (EMR). Dates that participants completed a colonoscopy are extracted from the EMR.

Outcome measures

Measure	Tailored DVD n=123 Participants Tailored digital video disc (DVD) DVD: A 20 minute tailored DVD titled "Approaches to Colon Testing" is viewed by participants. It is designed to encourage CRC screening uptake by colonoscopy or FIT by increasing the participant's CRC knowledge and beliefs about the benefits of screening, reducing barriers to screening, and increasing self-efficacy for screening by demonstrating how these tests are performed.	Tailored DVD + Patient Navigation n=120 Participants Tailored digital video disc (DVD) plus Patient Navigation by a population health nurse in the healthcare system DVD: A 20 minute tailored DVD titled "Approaches to Colon Testing" is viewed by participants. It is designed to encourage CRC screening uptake by colonoscopy or FIT by increasing the participant's CRC knowledge and beliefs about the benefits of screening, reducing barriers to screening, and increasing self-efficacy for screening by demonstrating how these tests are performed. Patient Navigation: Participants talk by telephone with a Patient Navigator who is a trained nurse. The Patient Navigator determines if participants viewed the tailored DVD and answers any questions about the content. The Patient Navigator then provides telephone counseling on CRC and screening tests to: (1) increase knowledge, perceived benefits, and self-efficacy; (2) reduce barriers; (3) enhance access; and (4) provide social support.	Usual Care n=128 Participants Care normally provided by a nurse in the endoscopy department of the healthcare system
Participants Completing Colonoscopy Per Electronic Medical Record Documentation	24 Participants	46 Participants	20 Participants

SECONDARY outcome

Timeframe: 12 months post-baseline interview

Population: All participants who completed a colonoscopy per EMR documentation. Analysis excludes 1 participant in Usual Care group whose BBPS score was missing.

Participants quality of bowel preparation is measured by the endoscopist during their colonoscopy procedure using the Boston Bowel Preparation Scale (BBPS). BBPS scores the total quality on a 10 point scale from 0-9. Higher scores indicate better quality of bowel preparation.

Outcome measures

Measure	Tailored DVD n=24 Participants Tailored digital video disc (DVD) DVD: A 20 minute tailored DVD titled "Approaches to Colon Testing" is viewed by participants. It is designed to encourage CRC screening uptake by colonoscopy or FIT by increasing the participant's CRC knowledge and beliefs about the benefits of screening, reducing barriers to screening, and increasing self-efficacy for screening by demonstrating how these tests are performed.	Tailored DVD + Patient Navigation n=46 Participants Tailored digital video disc (DVD) plus Patient Navigation by a population health nurse in the healthcare system DVD: A 20 minute tailored DVD titled "Approaches to Colon Testing" is viewed by participants. It is designed to encourage CRC screening uptake by colonoscopy or FIT by increasing the participant's CRC knowledge and beliefs about the benefits of screening, reducing barriers to screening, and increasing self-efficacy for screening by demonstrating how these tests are performed. Patient Navigation: Participants talk by telephone with a Patient Navigator who is a trained nurse. The Patient Navigator determines if participants viewed the tailored DVD and answers any questions about the content. The Patient Navigator then provides telephone counseling on CRC and screening tests to: (1) increase knowledge, perceived benefits, and self-efficacy; (2) reduce barriers; (3) enhance access; and (4) provide social support.	Usual Care n=19 Participants Care normally provided by a nurse in the endoscopy department of the healthcare system
Bowel Preparation Quality Rating Using Boston Bowel Preparation Scale	7.13 score on a scale Standard Deviation 1.90	6.59 score on a scale Standard Deviation 2.40	7.05 score on a scale Standard Deviation 2.44

SECONDARY outcome

Timeframe: 12 months post-baseline interview

Population: All participants who completed a colonoscopy per EMR documentation.

Participants quality of bowel preparation is measured by the endoscopist during their colonoscopy using a modification of the Aronchick rating scale. The Aronchick scale rates quality as 1=excellent, 2=good, 3=fair, or 4=poor. Some endoscopists choose to grade quality more generally as adequate vs. inadequate. To accommodate this variation, bowel preparation ratings have been dichotomized into adequate (excellent, good, fair, or adequate ratings) vs. inadequate (poor or inadequate ratings). Adequate is scored as 1 and indicates better quality of bowel preparation than inadequate which is scored as 0.

Outcome measures

Measure	Tailored DVD n=24 Participants Tailored digital video disc (DVD) DVD: A 20 minute tailored DVD titled "Approaches to Colon Testing" is viewed by participants. It is designed to encourage CRC screening uptake by colonoscopy or FIT by increasing the participant's CRC knowledge and beliefs about the benefits of screening, reducing barriers to screening, and increasing self-efficacy for screening by demonstrating how these tests are performed.	Tailored DVD + Patient Navigation n=46 Participants Tailored digital video disc (DVD) plus Patient Navigation by a population health nurse in the healthcare system DVD: A 20 minute tailored DVD titled "Approaches to Colon Testing" is viewed by participants. It is designed to encourage CRC screening uptake by colonoscopy or FIT by increasing the participant's CRC knowledge and beliefs about the benefits of screening, reducing barriers to screening, and increasing self-efficacy for screening by demonstrating how these tests are performed. Patient Navigation: Participants talk by telephone with a Patient Navigator who is a trained nurse. The Patient Navigator determines if participants viewed the tailored DVD and answers any questions about the content. The Patient Navigator then provides telephone counseling on CRC and screening tests to: (1) increase knowledge, perceived benefits, and self-efficacy; (2) reduce barriers; (3) enhance access; and (4) provide social support.	Usual Care n=20 Participants Care normally provided by a nurse in the endoscopy department of the healthcare system
Participants With Adequate Quality of Bowel Preparation Per Modified Aronchick Rating Scale	22 Participants	39 Participants	18 Participants

SECONDARY outcome

Timeframe: 12 months post-baseline interview

Population: Participants who completed a colonoscopy within 12 months of the baseline interview per EMR documentation and self-reported on colonoscopy-related anxiety during the 6 or 9 month post-baseline interview. Excludes 6 participants in the Tailored DVD group whose anxiety data were missing. Excludes 6 participants in the Tailored DVD + Patient Navigation group whose anxiety data were missing. Excludes 4 participants in the Usual Care group whose anxiety data were missing.

Colonoscopy-related procedural anxiety is measured by self-report using the 6-item short form of the State Anxiety Scale of the State-Trait Anxiety Inventory. Each item is scored from 1 to 4 (1=not at all; 4=very much so) with higher scores indicating greater anxiety.

Outcome measures

Measure	Tailored DVD n=16 Participants Tailored digital video disc (DVD) DVD: A 20 minute tailored DVD titled "Approaches to Colon Testing" is viewed by participants. It is designed to encourage CRC screening uptake by colonoscopy or FIT by increasing the participant's CRC knowledge and beliefs about the benefits of screening, reducing barriers to screening, and increasing self-efficacy for screening by demonstrating how these tests are performed.	Tailored DVD + Patient Navigation n=40 Participants Tailored digital video disc (DVD) plus Patient Navigation by a population health nurse in the healthcare system DVD: A 20 minute tailored DVD titled "Approaches to Colon Testing" is viewed by participants. It is designed to encourage CRC screening uptake by colonoscopy or FIT by increasing the participant's CRC knowledge and beliefs about the benefits of screening, reducing barriers to screening, and increasing self-efficacy for screening by demonstrating how these tests are performed. Patient Navigation: Participants talk by telephone with a Patient Navigator who is a trained nurse. The Patient Navigator determines if participants viewed the tailored DVD and answers any questions about the content. The Patient Navigator then provides telephone counseling on CRC and screening tests to: (1) increase knowledge, perceived benefits, and self-efficacy; (2) reduce barriers; (3) enhance access; and (4) provide social support.	Usual Care n=15 Participants Care normally provided by a nurse in the endoscopy department of the healthcare system
Colonoscopy-Related Procedural Anxiety for Participants Completing a Colonoscopy	2.46 units on a scale Standard Deviation 0.78	2.23 units on a scale Standard Deviation 0.67	2.28 units on a scale Standard Deviation 0.76

SECONDARY outcome

Timeframe: 12 months post-baseline interview

Population: Participants who completed a colonoscopy within 12 months of the baseline interview per EMR documentation and self-reported their satisfaction with the experience during the 6 or 9 month post-baseline interview. Excludes 6 participants in the Tailored DVD group whose satisfaction data were missing. Excludes 6 participants in the Tailored DVD + Patient Navigation group whose satisfaction data were missing. Excludes 4 participants in the Usual Care group whose satisfaction data were missing.

Satisfaction with the colonoscopy experience is measured by self-report using a single item developed by the research team. Satisfaction is rated from 1 to 4 where 1=not at all satisfied, 2=a little satisfied, 3=mostly satisfied, and 4=completely satisfied. Scores range from 1 to 4 with higher scores indicating greater satisfaction.

Outcome measures

Measure	Tailored DVD n=16 Participants Tailored digital video disc (DVD) DVD: A 20 minute tailored DVD titled "Approaches to Colon Testing" is viewed by participants. It is designed to encourage CRC screening uptake by colonoscopy or FIT by increasing the participant's CRC knowledge and beliefs about the benefits of screening, reducing barriers to screening, and increasing self-efficacy for screening by demonstrating how these tests are performed.	Tailored DVD + Patient Navigation n=40 Participants Tailored digital video disc (DVD) plus Patient Navigation by a population health nurse in the healthcare system DVD: A 20 minute tailored DVD titled "Approaches to Colon Testing" is viewed by participants. It is designed to encourage CRC screening uptake by colonoscopy or FIT by increasing the participant's CRC knowledge and beliefs about the benefits of screening, reducing barriers to screening, and increasing self-efficacy for screening by demonstrating how these tests are performed. Patient Navigation: Participants talk by telephone with a Patient Navigator who is a trained nurse. The Patient Navigator determines if participants viewed the tailored DVD and answers any questions about the content. The Patient Navigator then provides telephone counseling on CRC and screening tests to: (1) increase knowledge, perceived benefits, and self-efficacy; (2) reduce barriers; (3) enhance access; and (4) provide social support.	Usual Care n=15 Participants Care normally provided by a nurse in the endoscopy department of the healthcare system
Satisfaction With Colonoscopy Experience	3.38 units on a scale Standard Deviation 0.96	3.60 units on a scale Standard Deviation 0.78	3.13 units on a scale Standard Deviation 1.06

SECONDARY outcome

Timeframe: 12 months post-baseline interview

Population: All enrolled participants who completed the baseline interview and were randomized.

Number of participants completing a FIT is measured by electronic medical record review (EMR). Dates of FIT analysis are extracted from the EMR.

Outcome measures

Measure	Tailored DVD n=123 Participants Tailored digital video disc (DVD) DVD: A 20 minute tailored DVD titled "Approaches to Colon Testing" is viewed by participants. It is designed to encourage CRC screening uptake by colonoscopy or FIT by increasing the participant's CRC knowledge and beliefs about the benefits of screening, reducing barriers to screening, and increasing self-efficacy for screening by demonstrating how these tests are performed.	Tailored DVD + Patient Navigation n=120 Participants Tailored digital video disc (DVD) plus Patient Navigation by a population health nurse in the healthcare system DVD: A 20 minute tailored DVD titled "Approaches to Colon Testing" is viewed by participants. It is designed to encourage CRC screening uptake by colonoscopy or FIT by increasing the participant's CRC knowledge and beliefs about the benefits of screening, reducing barriers to screening, and increasing self-efficacy for screening by demonstrating how these tests are performed. Patient Navigation: Participants talk by telephone with a Patient Navigator who is a trained nurse. The Patient Navigator determines if participants viewed the tailored DVD and answers any questions about the content. The Patient Navigator then provides telephone counseling on CRC and screening tests to: (1) increase knowledge, perceived benefits, and self-efficacy; (2) reduce barriers; (3) enhance access; and (4) provide social support.	Usual Care n=128 Participants Care normally provided by a nurse in the endoscopy department of the healthcare system
Participants Completing a Fecal Immunochemical Test (FIT) Per Electronic Medical Record Documentation	15 Participants	13 Participants	8 Participants

SECONDARY outcome

Timeframe: 6-9 months post-baseline interview

Population: CRC screening self-reported during the 6 or 9 month follow-up telephone interview. Excludes 1 participant in Tailored DVD group due to data being collected outside of interview window. Excludes 1 participant in Usual Care group due to data being contradictory/invalid.

Number of participants who reported completing CRC screening by any test (defined as colonoscopy or FIT) during the 6 or 9 month post-baseline telephone interview.

Outcome measures

Measure	Tailored DVD n=101 Participants Tailored digital video disc (DVD) DVD: A 20 minute tailored DVD titled "Approaches to Colon Testing" is viewed by participants. It is designed to encourage CRC screening uptake by colonoscopy or FIT by increasing the participant's CRC knowledge and beliefs about the benefits of screening, reducing barriers to screening, and increasing self-efficacy for screening by demonstrating how these tests are performed.	Tailored DVD + Patient Navigation n=103 Participants Tailored digital video disc (DVD) plus Patient Navigation by a population health nurse in the healthcare system DVD: A 20 minute tailored DVD titled "Approaches to Colon Testing" is viewed by participants. It is designed to encourage CRC screening uptake by colonoscopy or FIT by increasing the participant's CRC knowledge and beliefs about the benefits of screening, reducing barriers to screening, and increasing self-efficacy for screening by demonstrating how these tests are performed. Patient Navigation: Participants talk by telephone with a Patient Navigator who is a trained nurse. The Patient Navigator determines if participants viewed the tailored DVD and answers any questions about the content. The Patient Navigator then provides telephone counseling on CRC and screening tests to: (1) increase knowledge, perceived benefits, and self-efficacy; (2) reduce barriers; (3) enhance access; and (4) provide social support.	Usual Care n=117 Participants Care normally provided by a nurse in the endoscopy department of the healthcare system
Participants Who Self-Reported Completing CRC Screening	48 Participants	59 Participants	43 Participants

SECONDARY outcome

Timeframe: 6-9 months post-baseline interview

Population: Colonoscopy completed per self-report during the 6 or 9 month follow-up telephone interview. Excludes 1 participant in Tailored DVD group due to data being collected outside of interview window. Excludes 1 participant in Usual Care group due to data being contradictory/invalid.

Number of participants who reported completing a colonoscopy during the 6 or 9 month post-baseline telephone interview.

Outcome measures

Measure	Tailored DVD n=101 Participants Tailored digital video disc (DVD) DVD: A 20 minute tailored DVD titled "Approaches to Colon Testing" is viewed by participants. It is designed to encourage CRC screening uptake by colonoscopy or FIT by increasing the participant's CRC knowledge and beliefs about the benefits of screening, reducing barriers to screening, and increasing self-efficacy for screening by demonstrating how these tests are performed.	Tailored DVD + Patient Navigation n=103 Participants Tailored digital video disc (DVD) plus Patient Navigation by a population health nurse in the healthcare system DVD: A 20 minute tailored DVD titled "Approaches to Colon Testing" is viewed by participants. It is designed to encourage CRC screening uptake by colonoscopy or FIT by increasing the participant's CRC knowledge and beliefs about the benefits of screening, reducing barriers to screening, and increasing self-efficacy for screening by demonstrating how these tests are performed. Patient Navigation: Participants talk by telephone with a Patient Navigator who is a trained nurse. The Patient Navigator determines if participants viewed the tailored DVD and answers any questions about the content. The Patient Navigator then provides telephone counseling on CRC and screening tests to: (1) increase knowledge, perceived benefits, and self-efficacy; (2) reduce barriers; (3) enhance access; and (4) provide social support.	Usual Care n=117 Participants Care normally provided by a nurse in the endoscopy department of the healthcare system
Participants Who Self-Reported Completing a Colonoscopy	26 Participants	46 Participants	27 Participants

SECONDARY outcome

Timeframe: 6-9 months post-baseline interview

Population: FIT completed per self-report during the 6 or 9 month follow-up telephone interview. Excludes 1 participant in Tailored DVD group due to data being collected outside of interview window. Excludes 1 participant in Usual Care group due to data being contradictory/invalid.

Number of participants who reported completing a FIT during the 6 or 9 month post-baseline telephone interview.

Outcome measures

Measure	Tailored DVD n=101 Participants Tailored digital video disc (DVD) DVD: A 20 minute tailored DVD titled "Approaches to Colon Testing" is viewed by participants. It is designed to encourage CRC screening uptake by colonoscopy or FIT by increasing the participant's CRC knowledge and beliefs about the benefits of screening, reducing barriers to screening, and increasing self-efficacy for screening by demonstrating how these tests are performed.	Tailored DVD + Patient Navigation n=103 Participants Tailored digital video disc (DVD) plus Patient Navigation by a population health nurse in the healthcare system DVD: A 20 minute tailored DVD titled "Approaches to Colon Testing" is viewed by participants. It is designed to encourage CRC screening uptake by colonoscopy or FIT by increasing the participant's CRC knowledge and beliefs about the benefits of screening, reducing barriers to screening, and increasing self-efficacy for screening by demonstrating how these tests are performed. Patient Navigation: Participants talk by telephone with a Patient Navigator who is a trained nurse. The Patient Navigator determines if participants viewed the tailored DVD and answers any questions about the content. The Patient Navigator then provides telephone counseling on CRC and screening tests to: (1) increase knowledge, perceived benefits, and self-efficacy; (2) reduce barriers; (3) enhance access; and (4) provide social support.	Usual Care n=117 Participants Care normally provided by a nurse in the endoscopy department of the healthcare system
Participants Who Self-Reported Completing a Fecal Immunochemical Test (FIT)	34 Participants	28 Participants	20 Participants

SECONDARY outcome

Timeframe: 6 months post-baseline interview

Population: Enrolled participants who completed the 6 month post-baseline interview. Excludes 1 participant in the Tailored DVD + Patient Navigation group whose data were missing. Excludes 1 participant in the Usual Care group due to the data being contradictory/invalid.

Change from baseline in knowledge of CRC and screening is measured at 6 months by self-report using a 9-item multidimensional scale. Each item is scored as 1=correct or 0=incorrect and summed to yield a scale score. Scores range from 0 to 9 with higher summated scores indicating greater knowledge of CRC and screening tests. The mean of the 9 items is calculated at baseline and 6 months post-baseline. Change from baseline equals the mean at 6 months minus the mean at baseline. Change can range from -9 to 9 with positive values indicating an increase in knowledge.

Outcome measures

Measure	Tailored DVD n=93 Participants Tailored digital video disc (DVD) DVD: A 20 minute tailored DVD titled "Approaches to Colon Testing" is viewed by participants. It is designed to encourage CRC screening uptake by colonoscopy or FIT by increasing the participant's CRC knowledge and beliefs about the benefits of screening, reducing barriers to screening, and increasing self-efficacy for screening by demonstrating how these tests are performed.	Tailored DVD + Patient Navigation n=94 Participants Tailored digital video disc (DVD) plus Patient Navigation by a population health nurse in the healthcare system DVD: A 20 minute tailored DVD titled "Approaches to Colon Testing" is viewed by participants. It is designed to encourage CRC screening uptake by colonoscopy or FIT by increasing the participant's CRC knowledge and beliefs about the benefits of screening, reducing barriers to screening, and increasing self-efficacy for screening by demonstrating how these tests are performed. Patient Navigation: Participants talk by telephone with a Patient Navigator who is a trained nurse. The Patient Navigator determines if participants viewed the tailored DVD and answers any questions about the content. The Patient Navigator then provides telephone counseling on CRC and screening tests to: (1) increase knowledge, perceived benefits, and self-efficacy; (2) reduce barriers; (3) enhance access; and (4) provide social support.	Usual Care n=108 Participants Care normally provided by a nurse in the endoscopy department of the healthcare system
Change in Knowledge of CRC and Screening	1.14 score on a scale Standard Error 0.24	1.32 score on a scale Standard Error 0.25	0.75 score on a scale Standard Error 0.23

SECONDARY outcome

Timeframe: 6 months post-baseline interview

Population: Enrolled participants who completed the 6 month post-baseline interview. Excludes 7 participants in the Tailored DVD group whose data were missing. Excludes 5 participants in the Tailored DVD + Patient Navigation group whose data were missing. Excludes 8 participants in the Usual Care group whose data were missing and 1 participant in the Usual Care group due to the data being contradictory/invalid.

Change from baseline in perceived risk for CRC is measured by self-report at 6 months using a 3-item scale. We ask participants how likely it is that they will get colon cancer sometime during their lifetime, within the next 10 years, and within the next 5 years. Each item is scored from 1 to 4 (1=very unlikely; 4=very likely). Higher scores indicate a higher perceived risk for getting CRC. The mean of the 3 items is calculated at baseline and 6 months. Change in perceived risk equals the mean at 6 months minus the mean at baseline. Change can range from -3 to 3 with positive values indicating an increase in perceived risk for getting CRC.

Outcome measures

Measure	Tailored DVD n=86 Participants Tailored digital video disc (DVD) DVD: A 20 minute tailored DVD titled "Approaches to Colon Testing" is viewed by participants. It is designed to encourage CRC screening uptake by colonoscopy or FIT by increasing the participant's CRC knowledge and beliefs about the benefits of screening, reducing barriers to screening, and increasing self-efficacy for screening by demonstrating how these tests are performed.	Tailored DVD + Patient Navigation n=90 Participants Tailored digital video disc (DVD) plus Patient Navigation by a population health nurse in the healthcare system DVD: A 20 minute tailored DVD titled "Approaches to Colon Testing" is viewed by participants. It is designed to encourage CRC screening uptake by colonoscopy or FIT by increasing the participant's CRC knowledge and beliefs about the benefits of screening, reducing barriers to screening, and increasing self-efficacy for screening by demonstrating how these tests are performed. Patient Navigation: Participants talk by telephone with a Patient Navigator who is a trained nurse. The Patient Navigator determines if participants viewed the tailored DVD and answers any questions about the content. The Patient Navigator then provides telephone counseling on CRC and screening tests to: (1) increase knowledge, perceived benefits, and self-efficacy; (2) reduce barriers; (3) enhance access; and (4) provide social support.	Usual Care n=100 Participants Care normally provided by a nurse in the endoscopy department of the healthcare system
Change in Perceived Risk for CRC	0.23 units on a scale Standard Deviation 0.11	0.03 units on a scale Standard Deviation 0.11	0.18 units on a scale Standard Deviation 0.11

SECONDARY outcome

Timeframe: 6 months post-baseline interview

Population: Participants who self-reported their colonoscopy-related anxiety during the 6 month post-baseline interview, regardless of their colonoscopy completion status. Excludes 1 participant in the Tailored DVD group whose data was missing. Excludes 2 participants in the Tailored DVD + Patient Navigation group whose data were missing. Excludes 2 participants in the Usual Care group due to data being missing for 1 participant and data being contradictory/invalid for 1 participant.

Change from baseline in colonoscopy-related procedural anxiety is measured at 6 months by self-report using the 6-item short form of the State Anxiety Scale of the State-Trait Anxiety Inventory. Each item is scored from 1 to 4 (1=not at all; 4=very much so) with higher scores indicating greater anxiety. The mean of the 6 items is calculated at baseline and 6 months post-baseline. Change from baseline is the mean at 6 months minus the mean at baseline. Change can range from -3 to 3 with positive values indicating an increase in anxiety.

Outcome measures

Measure	Tailored DVD n=92 Participants Tailored digital video disc (DVD) DVD: A 20 minute tailored DVD titled "Approaches to Colon Testing" is viewed by participants. It is designed to encourage CRC screening uptake by colonoscopy or FIT by increasing the participant's CRC knowledge and beliefs about the benefits of screening, reducing barriers to screening, and increasing self-efficacy for screening by demonstrating how these tests are performed.	Tailored DVD + Patient Navigation n=93 Participants Tailored digital video disc (DVD) plus Patient Navigation by a population health nurse in the healthcare system DVD: A 20 minute tailored DVD titled "Approaches to Colon Testing" is viewed by participants. It is designed to encourage CRC screening uptake by colonoscopy or FIT by increasing the participant's CRC knowledge and beliefs about the benefits of screening, reducing barriers to screening, and increasing self-efficacy for screening by demonstrating how these tests are performed. Patient Navigation: Participants talk by telephone with a Patient Navigator who is a trained nurse. The Patient Navigator determines if participants viewed the tailored DVD and answers any questions about the content. The Patient Navigator then provides telephone counseling on CRC and screening tests to: (1) increase knowledge, perceived benefits, and self-efficacy; (2) reduce barriers; (3) enhance access; and (4) provide social support.	Usual Care n=107 Participants Care normally provided by a nurse in the endoscopy department of the healthcare system
Change in Colonoscopy-Related Procedural Anxiety Regardless of Whether or Not Participants Had a Colonoscopy	-0.13 units on a scale Standard Deviation 0.09	-0.23 units on a scale Standard Deviation 0.10	-0.05 units on a scale Standard Deviation 0.09

SECONDARY outcome

Timeframe: 6 months post-baseline interview

Population: Enrolled participants who completed the 6 month post-baseline interview. Excludes 3 participants in the Tailored DVD group whose data was missing. Excludes 2 participants in the Tailored DVD + Patient Navigation group whose data was missing. Excludes 2 participants in the Usual Care group due to data being missing for 1 participant and data being contradictory/invalid for 1 participant.

Change from baseline in perceived benefits of CRC screening by colonoscopy is measured at 6 months by self-report using a 4-item scale. Each item is scored from 1 to 4 (1=strongly disagree; 4=strongly agree) and the mean of the 4 items calculated. Higher mean scores indicate greater perceived benefits of screening by colonoscopy. Change in perceived benefits equals the mean at 6 months minus the mean at baseline. Change can range from -3 to 3 with positive values indicating an increase in perceived benefits of screening by colonoscopy.

Outcome measures

Measure	Tailored DVD n=90 Participants Tailored digital video disc (DVD) DVD: A 20 minute tailored DVD titled "Approaches to Colon Testing" is viewed by participants. It is designed to encourage CRC screening uptake by colonoscopy or FIT by increasing the participant's CRC knowledge and beliefs about the benefits of screening, reducing barriers to screening, and increasing self-efficacy for screening by demonstrating how these tests are performed.	Tailored DVD + Patient Navigation n=93 Participants Tailored digital video disc (DVD) plus Patient Navigation by a population health nurse in the healthcare system DVD: A 20 minute tailored DVD titled "Approaches to Colon Testing" is viewed by participants. It is designed to encourage CRC screening uptake by colonoscopy or FIT by increasing the participant's CRC knowledge and beliefs about the benefits of screening, reducing barriers to screening, and increasing self-efficacy for screening by demonstrating how these tests are performed. Patient Navigation: Participants talk by telephone with a Patient Navigator who is a trained nurse. The Patient Navigator determines if participants viewed the tailored DVD and answers any questions about the content. The Patient Navigator then provides telephone counseling on CRC and screening tests to: (1) increase knowledge, perceived benefits, and self-efficacy; (2) reduce barriers; (3) enhance access; and (4) provide social support.	Usual Care n=107 Participants Care normally provided by a nurse in the endoscopy department of the healthcare system
Change in Perceived Benefits of CRC Screening by Colonoscopy	0.18 units on a scale Standard Deviation 0.08	0.16 units on a scale Standard Deviation 0.08	0.04 units on a scale Standard Deviation 0.08

SECONDARY outcome

Timeframe: 6 months post-baseline interview

Population: Enrolled participants who completed the 6 month post-baseline interview. Excludes 1 participant in the Tailored DVD group whose data were missing. Excludes 2 participants in the Tailored DVD + Patient Navigation group whose data were missing. Excludes 1 participant in Usual Care group due to data being contradictory/invalid.

Change from baseline in perceived barriers to CRC screening by colonoscopy is measured at 6 months by self-report using a 16-item scale. Each item is scored from 1 to 4 (1=strongly disagree; 4=strongly agree) and the mean of the 16 items calculated. Higher mean scores indicate greater perceived barriers to screening by colonoscopy. Change in perceived barriers equals the mean at 6 months minus the mean at baseline. Change can range from -3 to 3 with negative values indicating a decrease in perceived barriers to screening by colonoscopy.

Outcome measures

Measure	Tailored DVD n=92 Participants Tailored digital video disc (DVD) DVD: A 20 minute tailored DVD titled "Approaches to Colon Testing" is viewed by participants. It is designed to encourage CRC screening uptake by colonoscopy or FIT by increasing the participant's CRC knowledge and beliefs about the benefits of screening, reducing barriers to screening, and increasing self-efficacy for screening by demonstrating how these tests are performed.	Tailored DVD + Patient Navigation n=93 Participants Tailored digital video disc (DVD) plus Patient Navigation by a population health nurse in the healthcare system DVD: A 20 minute tailored DVD titled "Approaches to Colon Testing" is viewed by participants. It is designed to encourage CRC screening uptake by colonoscopy or FIT by increasing the participant's CRC knowledge and beliefs about the benefits of screening, reducing barriers to screening, and increasing self-efficacy for screening by demonstrating how these tests are performed. Patient Navigation: Participants talk by telephone with a Patient Navigator who is a trained nurse. The Patient Navigator determines if participants viewed the tailored DVD and answers any questions about the content. The Patient Navigator then provides telephone counseling on CRC and screening tests to: (1) increase knowledge, perceived benefits, and self-efficacy; (2) reduce barriers; (3) enhance access; and (4) provide social support.	Usual Care n=108 Participants Care normally provided by a nurse in the endoscopy department of the healthcare system
Change in Perceived Barriers to CRC Screening by Colonoscopy	-0.21 units on a scale Standard Deviation 0.08	0.01 units on a scale Standard Deviation 0.09	-0.15 units on a scale Standard Deviation 0.08

SECONDARY outcome

Timeframe: 6 months post-baseline interview

Population: Enrolled participants who completed the 6 month post-baseline interview. Excludes 1 participant in the Tailored DVD group whose data were missing. Excludes 2 participants in the Tailored DVD + Patient Navigation group whose data were missing. Excludes 1 participant in Usual Care group due to data being contradictory/invalid.

Change from baseline in perceived self-efficacy for colonoscopy is measured at 6 months by self-report using an 11-item scale. Each item is scored from 1 to 4 (1=not at all sure; 4=very sure) and the mean of the 11 items calculated. Higher mean scores indicate greater perceived self-efficacy for screening by colonoscopy. Change in perceived self-efficacy equals the mean at 6 months minus the mean at baseline. Change can range from -3 to 3 with positive values indicating an increase in perceived self-efficacy for screening by colonoscopy.

Outcome measures

Measure	Tailored DVD n=92 Participants Tailored digital video disc (DVD) DVD: A 20 minute tailored DVD titled "Approaches to Colon Testing" is viewed by participants. It is designed to encourage CRC screening uptake by colonoscopy or FIT by increasing the participant's CRC knowledge and beliefs about the benefits of screening, reducing barriers to screening, and increasing self-efficacy for screening by demonstrating how these tests are performed.	Tailored DVD + Patient Navigation n=93 Participants Tailored digital video disc (DVD) plus Patient Navigation by a population health nurse in the healthcare system DVD: A 20 minute tailored DVD titled "Approaches to Colon Testing" is viewed by participants. It is designed to encourage CRC screening uptake by colonoscopy or FIT by increasing the participant's CRC knowledge and beliefs about the benefits of screening, reducing barriers to screening, and increasing self-efficacy for screening by demonstrating how these tests are performed. Patient Navigation: Participants talk by telephone with a Patient Navigator who is a trained nurse. The Patient Navigator determines if participants viewed the tailored DVD and answers any questions about the content. The Patient Navigator then provides telephone counseling on CRC and screening tests to: (1) increase knowledge, perceived benefits, and self-efficacy; (2) reduce barriers; (3) enhance access; and (4) provide social support.	Usual Care n=108 Participants Care normally provided by a nurse in the endoscopy department of the healthcare system
Change in Perceived Self-Efficacy for CRC Screening by Colonoscopy	0.15 units on a scale Standard Deviation 0.07	0.20 units on a scale Standard Deviation 0.08	0.06 units on a scale Standard Deviation 0.07

SECONDARY outcome

Timeframe: 6 months post-baseline interview

Population: Enrolled participants who completed the 6 month post-baseline interview. Excludes 6 participants in the Tailored DVD group whose data were missing. Excludes 5 participants in the Tailored DVD + Patient Navigation group whose data were missing. Excludes 2 participants in the Usual Care group whose data were missing and 1 participant in Usual Care group due to data being contradictory/invalid.

Change from baseline in perceived benefits of CRC screening by FIT is measured at 6 months by self-report using a 3-item scale. Each item is scored from 1 to 4 (1=strongly disagree; 4=strongly agree) and the mean of the 3 items calculated. Higher mean scores indicate greater perceived benefits of screening by FIT. Change in perceived benefits equals the mean at 6 months minus the mean at baseline. Change can range from -3 to 3 with positive values indicating an increase in perceived benefits for screening by FIT.

Outcome measures

Measure	Tailored DVD n=87 Participants Tailored digital video disc (DVD) DVD: A 20 minute tailored DVD titled "Approaches to Colon Testing" is viewed by participants. It is designed to encourage CRC screening uptake by colonoscopy or FIT by increasing the participant's CRC knowledge and beliefs about the benefits of screening, reducing barriers to screening, and increasing self-efficacy for screening by demonstrating how these tests are performed.	Tailored DVD + Patient Navigation n=90 Participants Tailored digital video disc (DVD) plus Patient Navigation by a population health nurse in the healthcare system DVD: A 20 minute tailored DVD titled "Approaches to Colon Testing" is viewed by participants. It is designed to encourage CRC screening uptake by colonoscopy or FIT by increasing the participant's CRC knowledge and beliefs about the benefits of screening, reducing barriers to screening, and increasing self-efficacy for screening by demonstrating how these tests are performed. Patient Navigation: Participants talk by telephone with a Patient Navigator who is a trained nurse. The Patient Navigator determines if participants viewed the tailored DVD and answers any questions about the content. The Patient Navigator then provides telephone counseling on CRC and screening tests to: (1) increase knowledge, perceived benefits, and self-efficacy; (2) reduce barriers; (3) enhance access; and (4) provide social support.	Usual Care n=106 Participants Care normally provided by a nurse in the endoscopy department of the healthcare system
Change in Perceived Benefits of CRC Screening by FIT	0.08 units on a scale Standard Deviation 0.10	0.07 units on a scale Standard Deviation 0.11	-0.02 units on a scale Standard Deviation 0.10

SECONDARY outcome

Timeframe: 6 months post-baseline interview

Population: Enrolled participants who completed the 6 month post-baseline interview. Excludes 1 participant in the Tailored DVD group whose data were missing. Excludes 2 participants in the Tailored DVD + Patient Navigation group whose data were missing. Excludes 1 participant in Usual Care group due to data being contradictory/invalid.

Change from baseline in perceived barriers to CRC screening by FIT is measured at 6 months by self-report using a 10-item scale. Each item is scored from 1 to 4 (1=strongly disagree; 4=strongly agree) and the mean of the 10 items calculated. Higher mean scores indicate greater perceived barriers to screening by FIT. Change in perceived barriers equals the mean at 6 months minus the mean at baseline. Change can range from -3 to 3 with negative values indicating a decrease in perceived barriers to screening by FIT.

Outcome measures

Measure	Tailored DVD n=92 Participants Tailored digital video disc (DVD) DVD: A 20 minute tailored DVD titled "Approaches to Colon Testing" is viewed by participants. It is designed to encourage CRC screening uptake by colonoscopy or FIT by increasing the participant's CRC knowledge and beliefs about the benefits of screening, reducing barriers to screening, and increasing self-efficacy for screening by demonstrating how these tests are performed.	Tailored DVD + Patient Navigation n=93 Participants Tailored digital video disc (DVD) plus Patient Navigation by a population health nurse in the healthcare system DVD: A 20 minute tailored DVD titled "Approaches to Colon Testing" is viewed by participants. It is designed to encourage CRC screening uptake by colonoscopy or FIT by increasing the participant's CRC knowledge and beliefs about the benefits of screening, reducing barriers to screening, and increasing self-efficacy for screening by demonstrating how these tests are performed. Patient Navigation: Participants talk by telephone with a Patient Navigator who is a trained nurse. The Patient Navigator determines if participants viewed the tailored DVD and answers any questions about the content. The Patient Navigator then provides telephone counseling on CRC and screening tests to: (1) increase knowledge, perceived benefits, and self-efficacy; (2) reduce barriers; (3) enhance access; and (4) provide social support.	Usual Care n=108 Participants Care normally provided by a nurse in the endoscopy department of the healthcare system
Change in Perceived Barriers to CRC Screening by FIT	-0.18 units on a scale Standard Deviation 0.09	-0.11 units on a scale Standard Deviation 0.09	-0.16 units on a scale Standard Deviation 0.09

SECONDARY outcome

Timeframe: 6 months post-baseline interview

Population: Enrolled participants who completed the 6 month post-baseline interview. Excludes 1 participant in the Tailored DVD group whose data were missing. Excludes 2 participants in the Tailored DVD + Patient Navigation group whose data were missing. Excludes 1 participant in Usual Care group due to data being contradictory/invalid.

Change from baseline in perceived self-efficacy for CRC screening by FIT is measured at 6 months by self-report using a 7-item scale. Each item is scored from 1 to 4 (1=not at all sure; 4=very sure) and the mean of the 7 items calculated. Higher mean scores indicate greater perceived self-efficacy for screening by FIT. Change in perceived self-efficacy equals the mean at 6 months minus the mean at baseline. Change can range from -3 to 3 with positive values indicating an increase in perceived self-efficacy for screening by FIT.

Outcome measures

Measure	Tailored DVD n=92 Participants Tailored digital video disc (DVD) DVD: A 20 minute tailored DVD titled "Approaches to Colon Testing" is viewed by participants. It is designed to encourage CRC screening uptake by colonoscopy or FIT by increasing the participant's CRC knowledge and beliefs about the benefits of screening, reducing barriers to screening, and increasing self-efficacy for screening by demonstrating how these tests are performed.	Tailored DVD + Patient Navigation n=93 Participants Tailored digital video disc (DVD) plus Patient Navigation by a population health nurse in the healthcare system DVD: A 20 minute tailored DVD titled "Approaches to Colon Testing" is viewed by participants. It is designed to encourage CRC screening uptake by colonoscopy or FIT by increasing the participant's CRC knowledge and beliefs about the benefits of screening, reducing barriers to screening, and increasing self-efficacy for screening by demonstrating how these tests are performed. Patient Navigation: Participants talk by telephone with a Patient Navigator who is a trained nurse. The Patient Navigator determines if participants viewed the tailored DVD and answers any questions about the content. The Patient Navigator then provides telephone counseling on CRC and screening tests to: (1) increase knowledge, perceived benefits, and self-efficacy; (2) reduce barriers; (3) enhance access; and (4) provide social support.	Usual Care n=108 Participants Care normally provided by a nurse in the endoscopy department of the healthcare system
Change in Perceived Self-Efficacy for CRC Screening by FIT	0.07 units on a scale Standard Deviation 0.07	0.18 units on a scale Standard Deviation 0.07	0.10 units on a scale Standard Deviation 0.06

Adverse Events

Tailored DVD

Serious events: 0 serious events

Other events: 0 other events

Deaths: 2 deaths

Tailored DVD + Patient Navigation

Serious events: 0 serious events

Other events: 0 other events

Deaths: 4 deaths

Usual Care

Serious events: 0 serious events

Other events: 0 other events

Deaths: 2 deaths

Serious adverse events

Adverse event data not reported

Other adverse events

Adverse event data not reported

Additional Information

Susan M. Rawl, PhD, RN, FAAHB, FAAN

Indiana University

Phone: 317-278-2217

Email: srawl@iu.edu

Results disclosure agreements

• Principal investigator is a sponsor employee
• Publication restrictions are in place