Effects of Intensity-matched Agility and Cycling Exercise Training on PD Patients' Clinical Symptoms, Posture, and Mobility
NCT ID: NCT03193268
Last Updated: 2020-05-04
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.
COMPLETED
NA
2 participants
INTERVENTIONAL
2017-10-15
2017-11-21
Brief Summary
Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.
Hypothesis
1. The inclusion of a Borg-scale/heart-rate matched active control group will allow us to test the idea that, in addition to a fitness element, the reflexive movements that chellenge PD patients' sensorimotor system will improve patients' clinical symptoms, posture, and mobility more than fitness training and that such lasting effects will be superior in the agility compared with the fitness-control group. This hypothesis emered from the idea that the favorable results in the currently under review paper may be in part due to a simple conditioning effect instead of a specific motor learning effect caused by the xbox training.
2. If feasible, i.e., if there is a lerge enough pool of patients to randomize, a balance training group will be also added to test the idea that the reflexive actions evoked by the agility program by xbox exergaming still produce superior adaptations vs. the balance group because xbox forces patients to rapidly and reflexively execute movements (respond to cues, prompts), while balance training allows patients to stop, go, stop, and go and disrupt the continous execution of linked movements. The disruptions of movement chains could arise from small losses of balance on the unstabel surfaces, need for patients to re-initiate every movement element of a sequence, planning each movement element. It is not clear yet how it woul be possible to match all three intervention groups on Borg/heart rate intensity.
Related Clinical Trials
Explore similar clinical trials based on study characteristics and research focus.
Compare the Effects of Agility and Cycling Exercise Training on Mobility and Balance in PD and Healthy Old Adults
NCT03427762
Evaluation of the Impact of a Personalized Program of Adapted Physical Activates in Patients With Parkinson Disease
NCT03244813
Cycling in Parkinson's Disease
NCT02175082
Tailoring Upper Limb Exercise Advice for People With Parkinson Disease
NCT06472843
Effects Resistance Training on Motor Control and Cognition
NCT03017365
Detailed Description
Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.
Fitness: A stationary bicycle ergometer program that includes visual stimulation in the form of watching nature programs and movies to account for visual stimulus in Agility group. Mean heart rate and Borg scale readings from Agility group will form the target intensity.
Control: No-exercise, measurment-only control group.
Conditions
See the medical conditions and disease areas that this research is targeting or investigating.
Study Design
Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.
RANDOMIZED
PARALLEL
TREATMENT
SINGLE
Study Groups
Review each arm or cohort in the study, along with the interventions and objectives associated with them.
High intensity agility group
Exercise therapy
Single-blind RTC of PD patients
The groups participate in observation for 5 weeks. Two groups take part in a motion therapy over the 5-week period.
Non-agility cycling group
Parkinson's Bicycle Group, which takes 1 hour of exercise every day for 5 weeks
cycling
Patients must undergo a daily exercise cycle of 1 hour during the intervention
No-exercise control group
Control Parkinson's disease control group thad will not receive exercise treatment
No interventions assigned to this group
Interventions
Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.
Single-blind RTC of PD patients
The groups participate in observation for 5 weeks. Two groups take part in a motion therapy over the 5-week period.
cycling
Patients must undergo a daily exercise cycle of 1 hour during the intervention
Eligibility Criteria
Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.
Inclusion Criteria
* Hoenh Yahr scale of 2-3,
* instability problem,
Exclusion Criteria
55 Years
85 Years
ALL
Yes
Sponsors
Meet the organizations funding or collaborating on the study and learn about their roles.
Somogy Megyei Kaposi Mór Teaching Hospital
OTHER
Responsible Party
Identify the individual or organization who holds primary responsibility for the study information submitted to regulators.
Tollár József
Principal Investoigator
Locations
Explore where the study is taking place and check the recruitment status at each participating site.
Somogy Megyei Kaposi Mór Teaching Hospital
Kaposvár, Somogy County, Hungary
Countries
Review the countries where the study has at least one active or historical site.
References
Explore related publications, articles, or registry entries linked to this study.
Ernst M, Folkerts AK, Gollan R, Lieker E, Caro-Valenzuela J, Adams A, Cryns N, Monsef I, Dresen A, Roheger M, Eggers C, Skoetz N, Kalbe E. Physical exercise for people with Parkinson's disease: a systematic review and network meta-analysis. Cochrane Database Syst Rev. 2024 Apr 8;4(4):CD013856. doi: 10.1002/14651858.CD013856.pub3.
Ernst M, Folkerts AK, Gollan R, Lieker E, Caro-Valenzuela J, Adams A, Cryns N, Monsef I, Dresen A, Roheger M, Eggers C, Skoetz N, Kalbe E. Physical exercise for people with Parkinson's disease: a systematic review and network meta-analysis. Cochrane Database Syst Rev. 2023 Jan 5;1(1):CD013856. doi: 10.1002/14651858.CD013856.pub2.
Related Links
Access external resources that provide additional context or updates about the study.
Description Related Info
Other Identifiers
Review additional registry numbers or institutional identifiers associated with this trial.
IKEB0014/2015
Identifier Type: -
Identifier Source: org_study_id
More Related Trials
Additional clinical trials that may be relevant based on similarity analysis.