Evaluation of CPP-ACP Prophylactic Effect on Enamel Surface During Orthodontic Treatment

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Clinical Phase

PHASE1

Total Enrollment

45 participants

Study Classification

INTERVENTIONAL

Study Start Date

2017-07-31

Study Completion Date

2018-01-31

Brief Summary

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This study is aiming in preventing the formation of WSL associated with orthodontic treatment which occurs to more than 50% of orthodontically treated patients through applying CPP-ACP on the enamel surface once every 2 weeks for 3 months.

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Detailed Description

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CPP-ACP will be applied on premolars to be extracted in orthodontic patients whose treatment plan indicates extraction of at least 2 premolaes of the maxillary arch. Application will continue on one premolar either the right or left one once every 2 weeks for the first 3 months of the treatment.

Conditions

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White Spot Lesion Enamel Hypomineralization

Study Design

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Allocation Method

NA

Intervention Model

SINGLE_GROUP

Primary Study Purpose

PREVENTION

Blinding Strategy

NONE

Study Groups

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CPP-ACP

Casein phosphopeptide amorphous calcium phosphate dental paste

Group Type EXPERIMENTAL

Casein Phosphopeptide-Amorphous Calcium Phosphate Dental Paste

Intervention Type DRUG

Application of CPP-ACP on one premolar once every 2 weeks for 3 months.

Interventions

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Casein Phosphopeptide-Amorphous Calcium Phosphate Dental Paste

Application of CPP-ACP on one premolar once every 2 weeks for 3 months.

Intervention Type DRUG

Eligibility Criteria

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Inclusion Criteria

* severe crowding
* Increased overjet
* Protruded maxillary base
* Sound maxillary premolars
* medically free
* molar classification class II
* Canine classification class II