Patients' Assessment of Satisfaction for Stroke Prevention in Atrial Fibrillation

NCT ID: NCT03187197

Last Updated: 2020-02-24

Study Results

Results available

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Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

1315 participants

Study Classification

OBSERVATIONAL

Study Start Date

2017-06-20

Study Completion Date

2019-01-11

Brief Summary

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To describe the treatment perception from patients with non-valvular atrial fibrillation (NVAF) receiving Pradaxa® or VKA for stroke prevention by using the self-estimation questionnaire of PACT-Q during a 6-month study period.

Detailed Description

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Conditions

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Atrial Fibrillation

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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Cohort A

consented patients with NVAF in Taiwan with a previous VKA therapy, followed by switching to Pradaxa®

Pradaxa®

Intervention Type DRUG

Dabigatran etexilate

Cohort B

patients being newly diagnosed with NVAF and initiated on Pradaxa®

Pradaxa®

Intervention Type DRUG

Dabigatran etexilate

Interventions

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Pradaxa®

Dabigatran etexilate

Intervention Type DRUG

Other Intervention Names

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Dabigatran etexilate

Eligibility Criteria

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Inclusion Criteria

Cohort A (patients switched from VKA to Pradaxa)

* Written informed consent prior to participation.
* Female or male patients ≥ 20 years of age with a diagnosis of non-valvular atrial fibrillation (NVAF).
* At least 3 months of continuous VKA treatment for stroke prevention prior to baseline assessment.
* Patients switched to Pradaxa prior to baseline assessment according to the physician's discretion and the Summary of Product Characteristics (SmPCs)/reimbursement criteria.

OR Cohort B (patients newly initiated Pradaxa or VKA)

* Written informed consent prior to participation.
* Female or male patients ≥ 20 years of age, newly diagnosed with NVAF, and no previous treatment for stroke prevention (no use of any OAC within 1 year prior to enrolment).
* Patients initiated stroke prevention treatment with Pradaxa or VKA according to the physician's discretion and the SmPCs/reimbursement criteria.

Exclusion Criteria

* Contraindication to the use of Pradaxa® or VKA as described in the SmPCs.
* Patients receiving Pradaxa® or VKA for any other condition than stroke prevention in NVAF.
* Current participation in any clinical trial of a drug or device.
* Current participation in an AF-related registry, e.g. the Gloria AF program.
Minimum Eligible Age

20 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Boehringer Ingelheim

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Locations

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Chang-Hua Christian Hospital

Changhua, , Taiwan

Site Status

Show Chwan Memorial Hospital

Changhua, , Taiwan

Site Status

Chia-Yi Christian Hospital

Chia-Yi City, , Taiwan

Site Status

Hsinchu MacKay Memorial Hospital

Hsinchu, , Taiwan

Site Status

National Taiwan University Hospital-Hsin-Chu Branch

Hsinchu, , Taiwan

Site Status

Kaohsiung Medical University Chung-Ho Memorial Hospital

Kaohsiung City, , Taiwan

Site Status

E-Da Hospital

Kaohsiung City, , Taiwan

Site Status

Kaohsiung Chang Gung Memorial Hospital

Kaohsiung City, , Taiwan

Site Status

Far Eastern Memorial Hospital

New Taipei City, , Taiwan

Site Status

Taipei Medical University-Shuang Ho Hospital

New Taipei City, , Taiwan

Site Status

China Medical University Hospital

Taichung, , Taiwan

Site Status

Taichung Veterans General Hospital

Taichung, , Taiwan

Site Status

NCKUH

Tainan City, , Taiwan

Site Status

Chi Mei Medical Center

Tainan City, , Taiwan

Site Status

Tainan Municipal An-Nan Hospital

Tainan City, , Taiwan

Site Status

National Taiwan University Hospital

Taipei, , Taiwan

Site Status

Mackay Memorial Hospital

Taipei, , Taiwan

Site Status

Taipei Medical University Hospital

Taipei, , Taiwan

Site Status

Taipe Veterans General Hospital

Taipei, , Taiwan

Site Status

Tri-Service General Hospital

Taipei, , Taiwan

Site Status

Shin Kong International HealthCare Center

Taipei, , Taiwan

Site Status

Taipei Municipal Wanfang Hospital

Taipei, , Taiwan

Site Status

Chang Gung Memorial Hospital(TaoYuan)

Taoyuan District, , Taiwan

Site Status

National Taiwan University Hospital Yun-Lin Branch

Yunlin County, , Taiwan

Site Status

Countries

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Taiwan

References

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Lee CW, Liu ME, Lee TM, Chang RY, Huang CY, Hu YF, Yeh HI. Patient satisfaction with dabigatrean and warfarin for stroke prevention in atrial fibrillation: Taiwan PASSION study. J Chin Med Assoc. 2021 Apr 1;84(4):375-382. doi: 10.1097/JCMA.0000000000000496.

Reference Type DERIVED
PMID: 33784265 (View on PubMed)

Provided Documents

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Document Type: Statistical Analysis Plan

View Document

Document Type: Study Protocol

View Document

Other Identifiers

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1160-0286

Identifier Type: -

Identifier Source: org_study_id

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