Postmarketing Safety Study of Hemoporfin in Patients With Port Wine Stain

NCT ID: NCT03181984

Last Updated: 2023-12-20

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

PHASE4

Total Enrollment

501 participants

Study Classification

INTERVENTIONAL

Study Start Date

2017-08-31

Study Completion Date

2023-04-19

Brief Summary

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This study is to provide safety information of hemoporfin during the post-marketing period as required by China Food and Drug Administration (CFDA) regulations in order to identify any potential drug related treatment factors in the Chinese population, such as unknown/unexpected adverse reactions, the incidence of adverse reactions under the routine drug uses.

Detailed Description

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Conditions

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Port-Wine Stain

Study Design

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Allocation Method

NA

Intervention Model

SINGLE_GROUP

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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Hemoporfin

Group Type EXPERIMENTAL

Hemoporfin

Intervention Type DRUG

Hemoporfin mediated photodynamic therapy

Interventions

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Hemoporfin

Hemoporfin mediated photodynamic therapy

Intervention Type DRUG

Eligibility Criteria

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Inclusion Criteria

* Age range: 14 to 65 years-old;
* Clinically diagnosed of Port-wine Stain;
* Patients receiving hemoporfin based upon the clinical judgment of the investigator;
* Written informed consent signed and agreed to receive periodic follow-up

Exclusion Criteria

* Allergy to porphyrins and analogues; Photosensitivity; Porphyria; Allergic constitution;
* Scar diathesis;
* Pregnancy or unwilling to adopt reliable contraceptive measures during the month after drug application;
* Be judged not suitable to participate the study by the investigators
Minimum Eligible Age

14 Years

Maximum Eligible Age

65 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Shanghai Fudan-Zhangjiang Bio-Pharmaceutical Co., Ltd.

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Xuejun Zhu

Role: PRINCIPAL_INVESTIGATOR

Peking University First Hospital

Jining Tao

Role: STUDY_DIRECTOR

Shanghai Fudan-Zhangjiang Bio-Pharmaceutical Co., Ltd.

Locations

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The 2nd Affiliated Hospital of Harbin Medical University

Harbin, Heilongjiang, China

Site Status

Affiliated Hospital of Hebei Medical College of traditional Chinese Medicine

Shijiazhuang, Herbei, China

Site Status

Wuxi People's Hospital

Wuxi, Jiangsu, China

Site Status

West China Hospital, Sichuan University

Chengdu, Sichuan, China

Site Status

Peking University First Hospital

Beijing, , China

Site Status

PLA Army General Hospital

Beijing, , China

Site Status

Shanghai Dermatology Hospital

Shanghai, , China

Site Status

Countries

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China

Other Identifiers

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HMME-S1612

Identifier Type: -

Identifier Source: org_study_id