Trial Outcomes & Findings for "Ounce-equivalents" in the Protein Foods Group: Benefits of Quality (NCT NCT03179462)

NCT ID: NCT03179462

Last Updated: 2021-12-06

Results Overview

Net protein synthesis rate is determined in the 4.5-hours basal fasted period and 4-hours post-meal period over the 8.5-hour experimental period.

Recruitment status

COMPLETED

Study phase

NA

Target enrollment

27 participants

Primary outcome timeframe

Change from 4.5 to 8.5 hours.

Results posted on

2021-12-06

Participant Flow

Participant milestones

Participant milestones
Measure
Pork Intake
Subjects will consume 2 ounces of cooked lean pork following diet normalization for 3 days. Pork intake: Each participant will consume 2 ounces of cooked lean pork.
Mixed Nuts Intake
Subjects will consume 1 ounce of mixed nuts following diet normalization for 3 days. Mixed nuts intake: Each participant will consume 1 ounce of mixed nuts.
Tofu Intake
Subjects will consume 2 ounces of tofu following diet normalization for 3 days. Tofu intake: Each participant will consume 2 ounces of tofu.
Overall Study
STARTED
9
10
8
Overall Study
COMPLETED
8
8
8
Overall Study
NOT COMPLETED
1
2
0

Reasons for withdrawal

Reasons for withdrawal
Measure
Pork Intake
Subjects will consume 2 ounces of cooked lean pork following diet normalization for 3 days. Pork intake: Each participant will consume 2 ounces of cooked lean pork.
Mixed Nuts Intake
Subjects will consume 1 ounce of mixed nuts following diet normalization for 3 days. Mixed nuts intake: Each participant will consume 1 ounce of mixed nuts.
Tofu Intake
Subjects will consume 2 ounces of tofu following diet normalization for 3 days. Tofu intake: Each participant will consume 2 ounces of tofu.
Overall Study
screening failure
1
2
0

Baseline Characteristics

"Ounce-equivalents" in the Protein Foods Group: Benefits of Quality

Baseline characteristics by cohort

Baseline characteristics by cohort
Measure
Pork Intake
n=9 Participants
Subjects will consume 2 ounces of cooked lean pork following diet normalization for 3 days. Pork intake: Each participant will consume 2 ounces of cooked lean pork.
Mixed Nuts Intake
n=10 Participants
Subjects will consume 1 ounce of mixed nuts following diet normalization for 3 days. Mixed nuts intake: Each participant will consume 1 ounce of mixed nuts.
Tofu Intake
n=8 Participants
Subjects will consume 2 ounces of tofu following diet normalization for 3 days. Tofu intake: Each participant will consume 2 ounces of tofu.
Total
n=27 Participants
Total of all reporting groups
Age, Categorical
<=18 years
0 Participants
n=5 Participants
0 Participants
n=7 Participants
0 Participants
n=5 Participants
0 Participants
n=4 Participants
Age, Categorical
Between 18 and 65 years
9 Participants
n=5 Participants
10 Participants
n=7 Participants
8 Participants
n=5 Participants
27 Participants
n=4 Participants
Age, Categorical
>=65 years
0 Participants
n=5 Participants
0 Participants
n=7 Participants
0 Participants
n=5 Participants
0 Participants
n=4 Participants
Sex: Female, Male
Female
4 Participants
n=5 Participants
6 Participants
n=7 Participants
4 Participants
n=5 Participants
14 Participants
n=4 Participants
Sex: Female, Male
Male
5 Participants
n=5 Participants
4 Participants
n=7 Participants
4 Participants
n=5 Participants
13 Participants
n=4 Participants
Race/Ethnicity, Customized
Caucasian
7 Participants
n=5 Participants
7 Participants
n=7 Participants
7 Participants
n=5 Participants
21 Participants
n=4 Participants
Race/Ethnicity, Customized
Black/African American
2 Participants
n=5 Participants
2 Participants
n=7 Participants
1 Participants
n=5 Participants
5 Participants
n=4 Participants
Race/Ethnicity, Customized
Asian
0 Participants
n=5 Participants
1 Participants
n=7 Participants
0 Participants
n=5 Participants
1 Participants
n=4 Participants
Race/Ethnicity, Customized
Other Race
0 Participants
n=5 Participants
0 Participants
n=7 Participants
0 Participants
n=5 Participants
0 Participants
n=4 Participants
Race/Ethnicity, Customized
Hispanic ethnicity
0 Participants
n=5 Participants
1 Participants
n=7 Participants
0 Participants
n=5 Participants
1 Participants
n=4 Participants
Race/Ethnicity, Customized
non-Hispanic ethnicity
9 Participants
n=5 Participants
9 Participants
n=7 Participants
8 Participants
n=5 Participants
26 Participants
n=4 Participants

PRIMARY outcome

Timeframe: Change from 4.5 to 8.5 hours.

Net protein synthesis rate is determined in the 4.5-hours basal fasted period and 4-hours post-meal period over the 8.5-hour experimental period.

Outcome measures

Outcome measures
Measure
Pork Intake
n=8 Participants
Subjects will consume 2 ounces of cooked lean pork following diet normalization for 3 days. Pork intake: Each participant will consume 2 ounces of cooked lean pork.
Mixed Nuts Intake
n=8 Participants
Subjects will consume 1 ounce of mixed nuts following diet normalization for 3 days. Mixed nuts intake: Each participant will consume 1 ounce of mixed nuts.
Tofu Intake
n=8 Participants
Subjects will consume 2 ounces of tofu following diet normalization for 3 days. Tofu intake: Each participant will consume 2 ounces of tofu.
Net Protein Synthesis Rate
8.65 grams
Standard Deviation 1.6
1.97 grams
Standard Deviation 1.04
5.69 grams
Standard Deviation 0.54

Adverse Events

Pork Intake

Serious events: 0 serious events
Other events: 0 other events
Deaths: 0 deaths

Mixed Nuts Intake

Serious events: 0 serious events
Other events: 0 other events
Deaths: 0 deaths

Tofu Intake

Serious events: 0 serious events
Other events: 0 other events
Deaths: 0 deaths

Serious adverse events

Adverse event data not reported

Other adverse events

Adverse event data not reported

Additional Information

David D.Church, Ph.D.

University of Arkansas for Medical Sciences

Phone: 5015265709

Results disclosure agreements

  • Principal investigator is a sponsor employee
  • Publication restrictions are in place