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Microvascular Reactivity in Prepubertal Children

NCT ID: NCT03171441

Last Updated: 2017-05-31

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

98 participants

Study Classification

OBSERVATIONAL

Study Start Date

2013-01-31

Study Completion Date

2014-04-30

Brief Summary

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This is a cross-sectional study aimed to investigate microvascular reactivity in prepubertal children according to adiposity status.

Detailed Description

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The investigators aimed to investigate microvascular reactivity in prepubertal and to compare these data in different groups according to adiposity status. Firstly, The investigators recruited only children from 5 to 10 years at prepubertal status. After excluding those with exclusion criteria and the acceptance (from their parents) to participate in the study, a blood sample was collected and an appointment at BioVasc lab was programmed. At this day, participants were subject to nail fold videocapillaroscopy. A method used to investigate microvascular reactivity by a non-invasive mean. After this, participants children were followed to the outpatient's care unit to continue follow-up.

Conditions

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Child, Only Obesity Endothelial Dysfunction

Study Design

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Observational Model Type

OTHER

Study Time Perspective

CROSS_SECTIONAL

Study Groups

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Controls

eutrophic children

nailfold videocapillaroscopy

Intervention Type DIAGNOSTIC_TEST

non-invasive nailfold videocapillaroscopy

inflammatory biomarkers

Intervention Type DIAGNOSTIC_TEST

blood sample collection to asses leptin and C-reactive protein

Overweight

Overweight children

nailfold videocapillaroscopy

Intervention Type DIAGNOSTIC_TEST

non-invasive nailfold videocapillaroscopy

inflammatory biomarkers

Intervention Type DIAGNOSTIC_TEST

blood sample collection to asses leptin and C-reactive protein

Obese

Obese children

nailfold videocapillaroscopy

Intervention Type DIAGNOSTIC_TEST

non-invasive nailfold videocapillaroscopy

inflammatory biomarkers

Intervention Type DIAGNOSTIC_TEST

blood sample collection to asses leptin and C-reactive protein

Interventions

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nailfold videocapillaroscopy

non-invasive nailfold videocapillaroscopy

Intervention Type DIAGNOSTIC_TEST

inflammatory biomarkers

blood sample collection to asses leptin and C-reactive protein

Intervention Type DIAGNOSTIC_TEST

Other Intervention Names

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controls, overweight and obese groups controls, overweight and obese groups

Eligibility Criteria

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Inclusion Criteria

children aged from 5 to 10 years at prepubertal Tanner´s status

Exclusion Criteria

* puberty
* regular use of any medication
* hypertension
* heart disease
* renal and blood diseases .the presence of any acute or chronic inflammatory/infectious diseases. .presence of diabetes mellitus.
Minimum Eligible Age

5 Years

Maximum Eligible Age

10 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Eliete Bouskela

UNKNOWN

Sponsor Role collaborator

Rio de Janeiro State University

OTHER

Sponsor Role lead

Responsible Party

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Luiz Guilherme Kraemer de Aguiar

Associate professor

Responsibility Role PRINCIPAL_INVESTIGATOR

Other Identifiers

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2218-CEP/HUPE

Identifier Type: -

Identifier Source: org_study_id