Epithelioid Hemangioma of Bone And Soft Tissue

NCT ID: NCT03169595

Last Updated: 2017-05-30

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

70 participants

Study Classification

OBSERVATIONAL

Study Start Date

2015-10-07

Study Completion Date

2017-05-17

Brief Summary

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The controversy surrounding epithelioid hemangioma diagnosis stems from its somewhat aggressive clinical characteristics, including multifocal presentation and occasional lymph node involvement.

The investigators reviewed the clinicopathologic and radiologic characteristics of bone and soft tissue epithelioid hemangioma in patients treated at our institution with available tissue for molecular testing.

The hypothesis is that epithelioid hemangioma may present with multifocal involvement and rare loco-regional lymph node metastasis, but it remains a benign tumor with excellent prognosis.

Detailed Description

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The investigators retrospectively reviewed patients treated for epithelioid hemangioma of the bone and soft tissue in a single insitution. The purpose of this study is to evaluate the pathological, clinical, and radiological characteristics of epithelioid hemangioma arising within bone and soft tissue, in the first cohort of cases where the definitive diagnosis is supplemented by molecular techniques.

The hypothesis is that the improved knowledge regarding this rare entity can more definitively elucidate the benign biology of epithelioid hemangioma.

Conditions

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Epithelioid Hemangioma of Bone Epithelioid Hemangioma

Study Design

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Observational Model Type

CASE_ONLY

Study Time Perspective

RETROSPECTIVE

Interventions

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Surgery

Patients affected by epithelioid hemangioma treated with surgery

Intervention Type PROCEDURE

Eligibility Criteria

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Inclusion Criteria

* patients with epithelioid hemangioma of bone and soft tissue in the extremities and pelvis

Exclusion Criteria

* patients with epithelioid hemangioma of bone and soft tissue in the spine
Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Istituto Ortopedico Rizzoli

OTHER

Sponsor Role lead

Responsible Party

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Costantino Errani

MD, PhD.

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Davide Donati, MD

Role: STUDY_DIRECTOR

Istituto Ortopedico Rizzoli

Other Identifiers

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0033566

Identifier Type: -

Identifier Source: org_study_id

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