Plasmalyte-148 Solution and Blood Coagulation

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

12 participants

Study Classification

OBSERVATIONAL

Study Start Date

2017-05-15

Study Completion Date

2018-08-30

Brief Summary

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Fluids administered intravenously may alter whole blood coagulation. However, little is known about the dose-response relationships of hemodilution in plasmalyte-148 solution. Investigators have therefore performed the present study to measure the effect of a plasmalyte-148 solution on the coagulation pathway according to the hemodilution level using a rotational thromboelastometry (ROTEM®) tests.

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Detailed Description

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Conditions

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Blood Coagulation Disorder

Study Design

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Observational Model Type

CASE_CONTROL

Study Time Perspective

CROSS_SECTIONAL

Study Groups

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0% dilution

Blood specimen which was diluted with 0% level using a plasmalyte-148 solution

No interventions assigned to this group

20% dilution

Blood specimen which was diluted with 20% level using a plasmalyte-148 solution

Plasmalyte-148

Intervention Type OTHER

Venous blood is taken from 12 healthy volunteers and divided into four specimen bottles, which were diluted with different levels (0%, 20%, 40%, and 60%) using a plasmalyte-148 solution.

40% dilution

Blood specimen which was diluted with 40% level using a plasmalyte-148 solution

Plasmalyte-148

Intervention Type OTHER

Venous blood is taken from 12 healthy volunteers and divided into four specimen bottles, which were diluted with different levels (0%, 20%, 40%, and 60%) using a plasmalyte-148 solution.

60% dilution

Blood specimen which was diluted with 60% level using a plasmalyte-148 solution

Plasmalyte-148

Intervention Type OTHER

Venous blood is taken from 12 healthy volunteers and divided into four specimen bottles, which were diluted with different levels (0%, 20%, 40%, and 60%) using a plasmalyte-148 solution.

Interventions

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Plasmalyte-148

Venous blood is taken from 12 healthy volunteers and divided into four specimen bottles, which were diluted with different levels (0%, 20%, 40%, and 60%) using a plasmalyte-148 solution.

Intervention Type OTHER