Correlation of Solitary Dilated Duct at Mammography With Ultrasonography and Anatomopathological Findings

NCT ID: NCT03161392

Last Updated: 2019-07-30

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

135 participants

Study Classification

OBSERVATIONAL

Study Start Date

2016-03-16

Study Completion Date

2019-07-29

Brief Summary

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Mammograms performed at the Diagnostic Imaging Department of the "Instituto Brasileiro de Controle do Câncer" (IBCC - Brazilian Cancer Control Institute) will be prospectively evaluated. Patients who present a solitary dilated duct visualized by mammography will be submitted to breast ultrasonography. In case of detection of lesion, a percutaneous biopsy will be performed.

Detailed Description

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Purpose: To determinate the incidence, pathological significance and risk factors associated with the presence of solitary dilated duct visualized at mammography exam.

Methods: Mammograms performed at the Diagnostic Imaging Department of the "Instituto Brasileiro de Controle do Câncer" (IBCC - Brazilian Cancer Control Institute) will be prospectively evaluated. Patients who present a solitary dilated duct visualized by mammography will be included in the study. These patients will be recalled in order to be submitted to an ultrasonography directed to the mammographic finding. Patients who present lesions on ultrasonography will undergo method-guided percutaneous biopsy.

Patients with ductal ectasia, without evident lesions, will be followed for 2 years to evaluate stability by means of mammography or ultrasonography every 6-month intervals.

Conditions

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Mammary Duct Ectasia of Unspecified Breast Mammographic Findings Female

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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Ductal lesion

Subjects with a ductal lesion detected on ultrasonography.

Ultrasound-guided percutaneous biopsy

Intervention Type DIAGNOSTIC_TEST

Group "Ductal lesion" will be submitted to ultrasound-guided percutaneous biopsy and the specimen will be histologically analysed.

No ductal lesion

Subjects without a ductal lesion detected on ultrasonography

Follow-up

Intervention Type DIAGNOSTIC_TEST

Group "No ductal lesion" will be submitted to follow-up with periodic breast ultrasonography/mammography every 6 months for 2 years.

Interventions

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Follow-up

Group "No ductal lesion" will be submitted to follow-up with periodic breast ultrasonography/mammography every 6 months for 2 years.

Intervention Type DIAGNOSTIC_TEST

Ultrasound-guided percutaneous biopsy

Group "Ductal lesion" will be submitted to ultrasound-guided percutaneous biopsy and the specimen will be histologically analysed.

Intervention Type DIAGNOSTIC_TEST

Eligibility Criteria

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Inclusion Criteria

* Identification of a solitary dilated breast duct at mammography

Exclusion Criteria

* Previous breast surgery at same side of detection of dilated duct
Minimum Eligible Age

30 Years

Maximum Eligible Age

90 Years

Eligible Sex

FEMALE

Accepts Healthy Volunteers

Yes

Sponsors

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Instituto Brasileiro de Controle do Cancer

OTHER

Sponsor Role collaborator

Faculdade de Medicina do ABC

OTHER

Sponsor Role lead

Responsible Party

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Luciano de Melo Pompei'

Professor

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Luciano M Pompei, PhD

Role: STUDY_DIRECTOR

ABC Medicine School

Other Identifiers

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Ductoisolado_01

Identifier Type: -

Identifier Source: org_study_id

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