Safety and Efficacy of Immune Therapy for Condyloma

NCT ID: NCT03158480

Last Updated: 2017-06-29

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Clinical Phase

NA

Total Enrollment

80 participants

Study Classification

INTERVENTIONAL

Study Start Date

2017-06-25

Study Completion Date

2019-06-30

Brief Summary

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Cytokine-induced killer (CIK) cells will be co-cultured with HPV induced dendritic cells (DCs); HPV specific DC-CIK will be induced to Condylomata Acuminata patients using interferon, whose recurrence rate and total cost will be compared to Condylomata Acuminata patients only use interferon.

Detailed Description

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Conditions

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Condylomata Acuminata

Keywords

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DC-CIK interferon

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

TRIPLE

Participants Caregivers Outcome Assessors

Study Groups

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DC-CIK+interferon Group

dendritic cell-activated cytokine-induced killer cells (DC-CIK) immunotherapy plus interferon intervention

Group Type EXPERIMENTAL

DC-CIK immunotherapy

Intervention Type BIOLOGICAL

Cytokine-induced killer (CIK) cells are co-cultured with HPV induced dendritic cells (DCs); HPV specific DC-CIK will be induced to condylomata acuminata patients

Placebo+interferon Group

saline as placebo plus interferon intervention

Group Type PLACEBO_COMPARATOR

DC-CIK immunotherapy

Intervention Type BIOLOGICAL

Cytokine-induced killer (CIK) cells are co-cultured with HPV induced dendritic cells (DCs); HPV specific DC-CIK will be induced to condylomata acuminata patients

Interventions

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DC-CIK immunotherapy

Cytokine-induced killer (CIK) cells are co-cultured with HPV induced dendritic cells (DCs); HPV specific DC-CIK will be induced to condylomata acuminata patients

Intervention Type BIOLOGICAL

Eligibility Criteria

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Exclusion Criteria

\-
Minimum Eligible Age

20 Years

Maximum Eligible Age

50 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Shenzhen Second People's Hospital

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Locations

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Shenzhen Second Hospital

Shenzhen, Guangdong, China

Site Status RECRUITING

Countries

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China

Facility Contacts

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Lian Cuihong

Role: primary

Other Identifiers

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20173357201827

Identifier Type: -

Identifier Source: org_study_id