SAFEty and Efficacy of HOME-based Hospitalization Versus Inpatient Care for Patients With Acute Heart Failure in Chronic Heart Failure.

NCT ID: NCT03156686

Last Updated: 2023-02-15

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

TERMINATED

Clinical Phase

NA

Total Enrollment

10 participants

Study Classification

INTERVENTIONAL

Study Start Date

2017-06-01

Study Completion Date

2022-12-31

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

Evaluation of the efficacy, safety and and cost of home care versus conventional hospitalization care at 3-months in patients with worsening chronic heart failure.

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

Chronic heart failure (CHF) has an important socio-economic impact due to frequent hospital readmissions.

Hypothesis: Home care treatment (HC) will improve quality of live and decrease cost.

Methodology: Pilot, prospective, open, randomized controlled trial with 1-year follow-up for CHF patients admitted to 10 French hospital from March 2017 through February 2018, for acute decompensation of CHF. Patients will be randomly assigned to conventional hospital care or to the HC and treated with intravenous diuretics. Following discharge within 48 hours from the hospital, patients in the HC group will be treated at home. Follow-up will be conducted for both groups at discharge, 3 and 12 months after inclusion in the study.

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Heart Failure

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

Review each arm or cohort in the study, along with the interventions and objectives associated with them.

Control

Patients will be randomly assigned to conventional hospital care

Group Type NO_INTERVENTION

No interventions assigned to this group

Home care treatment

Patients will be randomly assigned to the HOME-based hospitalization and treated with intravenous diuretics. Following discharge within 48 hours from the hospital, patients in the HC group will be treated at home.

Group Type EXPERIMENTAL

HOME-based hospitalization

Intervention Type PROCEDURE

patients in Home care treatment (HC) group will be treated at home

Interventions

Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.

HOME-based hospitalization

patients in Home care treatment (HC) group will be treated at home

Intervention Type PROCEDURE

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

* Acute heart failure (with history of Chronic Heart Failure)
* Identified in the first 48 hours
* Eligible for home-care with "Hospitalisation à Domicile" within 4 days after hospitalization.
* Patient affiliated to social security and to complementary health insurance

Exclusion Criteria

* Under 18 years old
* Predominantly left-sided heart failure, dependent on oxygen because of the congestion
* Unexplored heart failure, indication of specific techniques (angiography) of device implantations (ICD, CRT).
* Severe cognitive disorders. Behavior disorders.
* Severe renal dysfunction with eGFR (MDRD) \< 15 mL/min/1.73m2
* Patient leaving alone
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

Meet the organizations funding or collaborating on the study and learn about their roles.

Agence Regionale de Sante d'Ile de France

OTHER_GOV

Sponsor Role collaborator

French Cardiology Society

OTHER

Sponsor Role lead

Responsible Party

Identify the individual or organization who holds primary responsibility for the study information submitted to regulators.

Responsibility Role SPONSOR

Principal Investigators

Learn about the lead researchers overseeing the trial and their institutional affiliations.

Thibaud DAMY, MD

Role: PRINCIPAL_INVESTIGATOR

CH HENRI MONDOR

Locations

Explore where the study is taking place and check the recruitment status at each participating site.

Hôpital Henri Mondor

Créteil, , France

Site Status

Hôpital Bicêtre

Le Kremlin-Bicêtre, , France

Site Status

Countries

Review the countries where the study has at least one active or historical site.

France

Other Identifiers

Review additional registry numbers or institutional identifiers associated with this trial.

2016-07

Identifier Type: -

Identifier Source: org_study_id

More Related Trials

Additional clinical trials that may be relevant based on similarity analysis.