The Ohio State University Dermatology Biorepository

NCT ID: NCT03146676

Last Updated: 2025-07-30

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Total Enrollment

175 participants

Study Classification

OBSERVATIONAL

Study Start Date

2017-04-19

Study Completion Date

2030-12-31

Brief Summary

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This study will create and extend a source of clinical specimens for the future study of inflammatory skin disorders.

Detailed Description

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A variety of molecular techniques can be used to investigate diseases by analyzing protein, DNA, and RNA. Flow cytometry, Polymerase chain reaction (PCR), histology and immunohistochemistry are assays which can identify specific cell populations and provide valuable information regarding the pathologic characteristics of those populations. Flow cytometry analyzes the surface markers of cells. Histology and immunohistochemistry further characterize surface and cellular molecules and aid in the diagnosis of certain skin diseases. Gene expression profiling allows investigators to examine the genes detectable to determine the function of the cells involved, and PCR techniques are useful for the diagnosis of certain conditions and for DNA analysis.

By procuring blood, skin tissue, and swab samples from patients with and without neoplastic and inflammatory skin disorders at the time of their appointments, the hypothesize that future translational research can be conducted on such specimens using the aforementioned techniques to further understand disease mechanisms in cutaneous disorders, and to potentially discover defective function and genetic mutations within cells from patients with neoplastic and inflammatory skin disorders. By establishing a tissue bank, we aim to lay the foundation for future work that will improve our understanding of the biology and natural history of neoplastic and inflammatory cutaneous diseases.

Conditions

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Hidradenitis Suppurativa

Study Design

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Observational Model Type

OTHER

Study Time Perspective

PROSPECTIVE

Eligibility Criteria

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Inclusion Criteria

* Seen by an Ohio State University (OSU) Dermatology provider on the main University Hospital campus, including the James Cancer Hospital, OSU Dermatology East, OSU Dermatology at the Ohio State Eye and Ear Institute, Martha Morehouse Medical Pavilion, and OSU Dermatology at Upper Arlington after the date of approval of this protocol
* Ability to provide informed consent, or parent or legal guardian capable of providing consent for child or mentally handicapped individuals
* Willingness to participate in a research study.

Exclusion Criteria

* Inability to provide informed consent
Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Ohio State University

OTHER

Sponsor Role lead

Responsible Party

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Ben H Kaffenberger

Dermatologist

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Benjamin Kaffenberger, MD

Role: PRINCIPAL_INVESTIGATOR

Dermatologist

Locations

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OSU Dermatology West

Columbus, Ohio, United States

Site Status RECRUITING

Countries

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United States

Central Contacts

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Erin Frey

Role: CONTACT

614-366-2025

Ashley Mintos

Role: CONTACT

614-366-9201

Facility Contacts

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Erin Frey

Role: primary

614-366-2025

Cerah McDaniels-Wilson

Role: backup

Other Identifiers

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2010H0331

Identifier Type: -

Identifier Source: org_study_id

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