Monitoring of Systemic or Organ Perfusion for Preterm Infants

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

85 participants

Study Classification

OBSERVATIONAL

Study Start Date

2017-05-08

Study Completion Date

2018-12-31

Brief Summary

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To investigate biomarker reflects systemic or specific organ perfusion well, we are going to the observational comparison study using several hemodynamic monitoring methods in the premature infants. It includes near-infrared spectroscopy (NIRS), pulse oximetry with perfusion index (PI) and pleth variability index (PVI) and functional echocardiography.

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Detailed Description

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Hemodynamic observational comparisons will be performed in 6 episodes below on each patient.

1. first 24 hours after birth
2. during red blood cell (RBC) transfusion: from 4 hours before to 4 hours after the transfusion
3. suspicion of necrotizing enterocolitis: from the suspicion point for 48 hours
4. suspicion of sepsis: from the suspicion point for 48 hours
5. oligouria (\< 1 mL/kg/hour of urine): for 48 hours
6. hypotension (mean blood pressure \< 30 mmHg): for 48 hours

Conditions

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Infant, Premature Hypoperfusion in Newborn Necrotizing Enterocolitis of Newborn Sepsis Newborn Oliguria Hypotension

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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Premature infant

premature infants with 32 weeks or less gestational age or 1,500 g or less birth weight, who born in the Inha university hospital and admit to the neonatal intensive care unit of the Inha university hospital

NIRS (near Infra-red spectroscopy)

Intervention Type DEVICE

1. NIRS, INVOS 5100 cerebral/somatic oximeter monitor (Somanetics Corp, Troy, Michigan, USA)
2. Radical-7 pulse oximeter (Masimo Corp, Irvine, CA, USA)
3. Echocardiography (Phillips HD 15 Ultrasound system, CA, USA)

Interventions

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NIRS (near Infra-red spectroscopy)

1. NIRS, INVOS 5100 cerebral/somatic oximeter monitor (Somanetics Corp, Troy, Michigan, USA)
2. Radical-7 pulse oximeter (Masimo Corp, Irvine, CA, USA)
3. Echocardiography (Phillips HD 15 Ultrasound system, CA, USA)

Intervention Type DEVICE