Weighted Blankets With Infants With NAS

NCT ID: NCT03113656

Last Updated: 2019-09-19

Study Results

Results available

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Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

16 participants

Study Classification

INTERVENTIONAL

Study Start Date

2017-07-14

Study Completion Date

2018-01-18

Brief Summary

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Infants with neonatal abstinence syndrome (NAS) who are cared for in a Neonatal Intensive Care Unit (NICU) often display symptoms including hyperactivity, irritability, jitteriness, poor feeding, and poor sleep patterns. The recommended first line of treatment to relieve these symptoms involves nonpharmacological interventions. The purpose of the current pilot study is to provide preliminary data to assist in the design of a larger scale study to examine one nonpharmacological intervention, weighted blankets. The pilot study will assess the feasibility of a cross-over randomized controlled design to study the impact of a weighted blanket on infants' symptoms of NAS.

The aims of the study are:

Aim1: To determine the feasibility of recruiting patients for a study evaluating the use of weighted blankets in the care of infants with NAS Aim 2: To determine the feasibility and safety of the study procedures Aim 3: To examine whether there is clinical benefit to using weighted blankets for the treatment of symptoms in infants with NAS.

After informed consent is obtained, infants will be randomized to have either a weighted blanket or a non-weighted blanket placed on them first. A cross-over design will be used so all infants will experience both the non-weighted and weighted blankets. Thirty minutes before each feeding, baseline vital signs and Finnegan score will be obtained. Then, a blanket (weighted or non-weighted) will be placed on the infant for 30 minutes. Infants will be directly monitored and on heart rate/respiratory rate monitors while the blanket is applied. Vital signs and Finnegan scores will be obtained at the end of 30 minutes of blanket placement, infants will be fed, and vital signs and Finnegan scores will be obtained again 30 minutes after the blanket was removed. Descriptive statistics will be used to determine the enrollment rate and feasibility of the protocol. Nonparametric statistics will be used to compare total Finnegan scores for infants with the weighted blanket applied compared to infants with a non-weighted blanket applied. Changes in Finnegan scores will be examined to estimate an effect size to use in a power analysis for a future larger effectiveness study.

Detailed Description

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Conditions

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Neonatal Abstinence Syndrome

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

CROSSOVER

Primary Study Purpose

OTHER

Blinding Strategy

NONE

Study Groups

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Weighted Blanket First

This group will receive the Weighted Blanket first and then the Non-weighted blanket

Group Type EXPERIMENTAL

Weighted Blanket

Intervention Type OTHER

Weighted blanket placed on infant for 30 minutes

Non-Weighted Blanket

Intervention Type OTHER

Non-Weighted blanket placed on infant for 30 minutes

Non-weighted Blanket First

This group will receive the Non-weighted Blanket first and then the Weighted blanket

Group Type EXPERIMENTAL

Weighted Blanket

Intervention Type OTHER

Weighted blanket placed on infant for 30 minutes

Non-Weighted Blanket

Intervention Type OTHER

Non-Weighted blanket placed on infant for 30 minutes

Interventions

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Weighted Blanket

Weighted blanket placed on infant for 30 minutes

Intervention Type OTHER

Non-Weighted Blanket

Non-Weighted blanket placed on infant for 30 minutes

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Admitted to the NICU
* Gestational age \> 37 weeks
* Positive maternal drug screen at delivery

Exclusion Criteria

* Clinical staff does not give permission to enroll the patient
* Had intrauterine growth restriction (IUGR)
* Has any medical diagnosis in addition to NAS diagnosis
* Has a weight below the 10th percentile
Minimum Eligible Age

37 Weeks

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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TriHealth Inc.

OTHER

Sponsor Role lead

Responsible Party

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Rachel Baker

Nurse Researcher

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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Good Samaritan Hospital

Cincinnati, Ohio, United States

Site Status

Countries

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United States

Provided Documents

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Document Type: Study Protocol and Statistical Analysis Plan

View Document

Other Identifiers

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17-008

Identifier Type: -

Identifier Source: org_study_id

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