The Association Between Nephrolithiasis and Periodontal Status

NCT ID: NCT03102086

Last Updated: 2018-05-16

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Total Enrollment

20 participants

Study Classification

OBSERVATIONAL

Study Start Date

2017-05-11

Study Completion Date

2019-01-31

Brief Summary

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Dental calculus is a calcified deposits firmly attached to teeth and implants surfaces. Dental calculus is strongly associated with periodontitis and considered to have indirect role in the pathogenesis of periodontal diseases. Dental calculus composed primarily of calcium phosphate mineral salts originated in the saliva covered by unmineralized bacterial layer. Composition of calculus varies from person to person and influenced by numerous variables such as: age, gender systemic disease and ethnic background.

Nephrolithiasis (kidney stones) are composed of insoluble salts of constituents of the forming urine. The most two frequent stone types are: Calcium oxalate (with a frequency of 15% -35%) and Calcium phosphate (5% -20%). The prevalence of kidney stones varies with race, sex, and geographic location. In the United States for men, kidney stone rates vary between 4%-9%, and for women, kidney stone rates range between 2%-4%.

Previous studies dealt with the connection between sialolithiasis and nephrolithiasis were inconclusive. To the authors' best knowledge no studies were done to examine the associations between nephrolithiasis and dental calculus. Thus, the aim of this study is to compare the mineral composition of both dental calculus and nephrolithiasis and determine whether nephrolithiasis composition may be linked to the periodontal status.

Detailed Description

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Conditions

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Periodontal Diseases Nephrolithiasis

Study Design

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Observational Model Type

CASE_ONLY

Study Time Perspective

CROSS_SECTIONAL

Interventions

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Scaling

Scaling of dental calculus

Intervention Type PROCEDURE

Eligibility Criteria

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Inclusion Criteria

* Patients diagnosed with nephrolithiasis
* Over 18 years old

Exclusion Criteria

* Pregnant woman, uncontrolled diabetes (HbA1c \> 7.5%), patients who received periodontal treatment in the past 6 months, smokers
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Rambam Health Care Campus

OTHER

Sponsor Role lead

Responsible Party

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machtei

Prof

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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Rambam Health Care Campus, Dept. of Periodontology

Haifa, , Israel

Site Status RECRUITING

Countries

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Israel

Facility Contacts

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prof. Eli Machtei, DMD

Role: primary

9720545503199

Other Identifiers

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0097-16-RMB

Identifier Type: -

Identifier Source: org_study_id

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