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Response Prediction After GKS in Patients With Vestibular Schwannoma Using DCE MR Imaging

NCT ID: NCT03097822

Last Updated: 2017-03-31

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Total Enrollment

90 participants

Study Classification

OBSERVATIONAL

Study Start Date

2017-01-31

Brief Summary

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Response Prediction after Gamma Knife Surgery (GKS) in Patients with Vestibular Schwannoma using Dynamic Contrast-Enhanced (DCE) MR Imaging

Detailed Description

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The purpose of this study was to evaluate the response of Gamma Knife Surgery to Ktrans, Ve, and Vp, which are indicators of permeability map obtained from dynamic contrast enhanced (DCE) MRI in patients with vestibular schwannoma .

Conditions

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Vestibular Schwannoma

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Eligibility Criteria

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Inclusion Criteria

* Patients with vestibular schwannoma, who underwent gamma knife surgery and pre-op dynamic contrast enhanced (DCE) MRI
* Patients with vestibular schwannoma, who received consent

Exclusion Criteria

* In addition to the vestibular schwannoma, if the brain has other underlying or systemic disease
* During the observation period, other treatments were performed other than gamma knife surgery
* If patients have a contraindication to MRI (eg, pacemaker, cochlear implants, hemodynamically unstable)
* Concomitant use of gadolinium MRI contrast agents (eg, renal insufficiency \[glomerular filtration rate \<30 ML / min\]), or if there was a side effect when using a contrast medium.
* Adults with impaired ability to cope
* If the images and medical records required for this study are not available or are not appropriate
Minimum Eligible Age

20 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Seoul National University Hospital

OTHER

Sponsor Role lead

Responsible Party

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Seung Hong Choi

SeoulNUH

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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SeungHong Choi, MD,PhD

Role: PRINCIPAL_INVESTIGATOR

Seoul National University Hospital(Radiology)

Central Contacts

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SeungHong Choi, MD,PhD

Role: CONTACT

Email: [email protected]

Other Identifiers

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H-1611-087-809

Identifier Type: -

Identifier Source: org_study_id