Clinical System Accuracy Evaluation With OneTouch® Verio Flex Blood Glucose Monitoring System (BGMS)

NCT ID: NCT03085251

Last Updated: 2017-09-26

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

109 participants

Study Classification

INTERVENTIONAL

Study Start Date

2017-03-16

Study Completion Date

2017-06-01

Brief Summary

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The objective of this study is the evaluation of system accuracy based on EN ISO 15197:2015 (ISO 15197:2013), clause 6.3 in which accuracy requirements and applicable test procedures for blood glucose monitoring systems intended for self-monitoring of blood glucose by patients are stipulated. ISO 15197:20132 was harmonized with the regulations of the European Union as EN ISO 15197:2015. This harmonization had no impact on the requirements and procedu¬res in ISO 15197:2013; changes were made to the foreword and an informative annex. In this study, system accuracy evaluation will be performed for OneTouch® Verio Flex (LifeScan Europe) on behalf of LifeScan Scotland Limited (customer) with three different reagent system lots.

Detailed Description

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Conditions

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Diabetes Mellitus

Study Design

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Allocation Method

NA

Intervention Model

SINGLE_GROUP

Primary Study Purpose

OTHER

Blinding Strategy

NONE

Study Groups

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Blood glucose measurement

Group Type EXPERIMENTAL

Blood glucose monitoring systems for self-testing (BGMS)

Intervention Type DEVICE

Measurement procedure

* Subjects will be asked to wash and dry their hands before the measurements.
* The measurement procedure for each reagent system lot of a BGMS will be as follows:
* Study personnel will collect a capillary blood sample from the subject's fingertip by skin puncture.
* Duplicate measurements on the sample will be consecutively performed with 2 test meters using reagent system units from the same vial / package.
* Capillary blood for measurements with all 3 test strip lots and for both comparison measurements will be taken from the same finger puncture.
* The sample will be applied to the reagent system units following specifications in the manufacturer's labelling.

Interventions

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Blood glucose monitoring systems for self-testing (BGMS)

Measurement procedure

* Subjects will be asked to wash and dry their hands before the measurements.
* The measurement procedure for each reagent system lot of a BGMS will be as follows:
* Study personnel will collect a capillary blood sample from the subject's fingertip by skin puncture.
* Duplicate measurements on the sample will be consecutively performed with 2 test meters using reagent system units from the same vial / package.
* Capillary blood for measurements with all 3 test strip lots and for both comparison measurements will be taken from the same finger puncture.
* The sample will be applied to the reagent system units following specifications in the manufacturer's labelling.

Intervention Type DEVICE

Other Intervention Names

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OneTouch® Verio Flex

Eligibility Criteria

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Inclusion Criteria

* Male or female, with type 1 diabetes, type 2 diabetes (or subjects without diabetes)
* Signed informed consent form
* Minimum age of 18 years
* Subjects are legally competent and capable to understand character, meaning and consequences of the study.
* If blood glucose values \< 80 mg/dl or \> 300 mg/dl shall be measured after short term alteration in insulin therapy:
* Male or female with type 1 diabetes and intensified insulin therapy or insulin pump therapy.
* Signature of subjects to document consent with these procedures on informed consent form.

Exclusion Criteria

* Pregnancy or lactation period
* Severe acute disease (at the study physician's discretion)
* Severe chronic disease with potential risk during the test procedures (at the study physician's discretion)
* Current constitution that compromises the subject's capability to participate in the study (at the study physician's discretion)
* Being unable to give informed consent
* \< 18 years
* Legally incompetent
* Being committed to an institution (e.g. psychiatric clinic)
* Language barriers potentially compromising an adequate compliance with study procedures
* Dependent on investigator or sponsor
* If blood glucose values \< 80 mg/dl shall be measured after short term alteration in insulin therapy (concentration category 2), subjects with type 1 diabetes, suffering from:
* Coronary heart disease
* Condition after myocardial infarction
* Condition after cerebral events
* Peripheral arterial occlusive disease
* Hypoglycemia unawareness
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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LifeScan

INDUSTRY

Sponsor Role collaborator

Institut für Diabetes-Technologie Forschungs- und Entwicklungsgesellschaft mbH an der Universität Ulm

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Locations

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Institut für Diabetes-Technologie Forschungs- und Entwicklungsgesellschaft mbH an der Universität Ulm

Ulm, Baden-Wurttemberg, Germany

Site Status

Countries

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Germany

Other Identifiers

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IDT-1653-LI

Identifier Type: -

Identifier Source: org_study_id