Trial Outcomes & Findings for Hemodynamic Effects of Blood Flow Variation in Continuous Renal Replacement Therapy (NCT NCT03078504)

NCT ID: NCT03078504

Last Updated: 2020-03-30

Results Overview

Change in mean arterial pressure from period 1 to period 2

Recruitment status

TERMINATED

Study phase

NA

Target enrollment

6 participants

Primary outcome timeframe

10 minutes

Results posted on

2020-03-30

Participant Flow

Participant milestones

Participant milestones
Measure
Experimental Arm
The patients will have the blood flow rate adjusted on CRRT gradually increased to assess the effect on hemodynamics continuous renal replacement therapy using System One (TM) setup (Nxstage): Participants who have been prescribed continuous renal replacement therapy will have hemodynamic parameters measured at various blood flow rates
Overall Study
STARTED
6
Overall Study
COMPLETED
6
Overall Study
NOT COMPLETED
0

Reasons for withdrawal

Withdrawal data not reported

Baseline Characteristics

Race and Ethnicity were not collected from any participant.

Baseline characteristics by cohort

Baseline characteristics by cohort
Measure
Experimental Arm
n=6 Participants
The patients will have the blood flow rate adjusted on CRRT gradually increased to assess the effect on hemodynamics continuous renal replacement therapy using System One (TM) setup (Nxstage): Participants who have been prescribed continuous renal replacement therapy will have hemodynamic parameters measured at various blood flow rates
Age, Continuous
67 years
STANDARD_DEVIATION 7 • n=6 Participants
Sex: Female, Male
Female
4 Participants
n=6 Participants
Sex: Female, Male
Male
2 Participants
n=6 Participants
Region of Enrollment
United States
6 participants
n=6 Participants
mean arterial pressure
79 mmHg
STANDARD_DEVIATION 12 • n=6 Participants

PRIMARY outcome

Timeframe: 10 minutes

Change in mean arterial pressure from period 1 to period 2

Outcome measures

Outcome measures
Measure
Experimental Arm
n=6 Participants
The patients will have the blood flow rate adjusted on CRRT gradually increased to assess the effect on hemodynamics continuous renal replacement therapy using System One (TM) setup (Nxstage): Participants who have been prescribed continuous renal replacement therapy will have hemodynamic parameters measured at various blood flow rates
Blood Pressure Change
-0.2 mmHg
Standard Deviation 2

Adverse Events

Experimental Arm

Serious events: 0 serious events
Other events: 0 other events
Deaths: 0 deaths

Serious adverse events

Adverse event data not reported

Other adverse events

Adverse event data not reported

Additional Information

Dr.Zafar Jamkhana

Saint Louis University

Phone: 314-577-8856

Results disclosure agreements

  • Principal investigator is a sponsor employee
  • Publication restrictions are in place