Coronary Artery Disease: a Case- Control Study

NCT ID: NCT03075566

Last Updated: 2017-03-09

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Total Enrollment

517 participants

Study Classification

OBSERVATIONAL

Study Start Date

2014-09-30

Study Completion Date

2017-12-31

Brief Summary

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Atherosclerosis is a chronic inflammatory condition, which is associated by the involvement of several pathological events, and alteration in the serum levels of pro- and anti-inflammatory, and lipid markers.

The investigators evaluated the contribution of serum biomarkers levels to the pathogenesis of coronary artery disease, namely their association with risk factors, clinical presentation, extent and severity of atherosclerotic changes accompanying coronary artery disease.

Detailed Description

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Conditions

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Coronary Artery Disease

Study Design

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Observational Model Type

CASE_CONTROL

Study Time Perspective

PROSPECTIVE

Interventions

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Healthy subjects

\- 207 healthy subjects were donors,(33.2±12.2 years) recruited from the Blood Bank Department of the University Hospital (Mahdia, Tunisia).

Intervention Type BIOLOGICAL

Patients

\- 310 subjects with CAD (60.3±11.0 years) were admitted to the Department of Cardiology, University Hospital (Monastir, Tunisia).

Intervention Type BIOLOGICAL

Eligibility Criteria

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Inclusion Criteria

* Coronary Artery Disease

Exclusion Criteria

* Severe respiratory disease
* Liver disease
* kidney disease
* Inflammatory diseases (infections, autoimmune disorders, malignancy).
Minimum Eligible Age

20 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Nadia Bouzidi, PhD

OTHER

Sponsor Role lead

Responsible Party

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Nadia Bouzidi, PhD

Bouzidi Nadia, PhD

Responsibility Role SPONSOR_INVESTIGATOR

Principal Investigators

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Salima Ferchichi, Pr

Role: STUDY_DIRECTOR

University of Monastir, Faculty of Pharmacy of Monastir, Tunisia

Locations

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Faculty of Pharmacy

Monastir, Ibn Sina Street, Tunisia

Site Status RECRUITING

Countries

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Tunisia

Central Contacts

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NADIA BOUZIDI, PhD

Role: CONTACT

21622987518

Facility Contacts

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NADIA BOUZIDI, PhD

Role: primary

21622987518

References

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Bouzidi N, Gamra H. Relationship between serum interleukin-6 levels and severity of coronary artery disease undergoing percutaneous coronary intervention. BMC Cardiovasc Disord. 2023 Nov 28;23(1):586. doi: 10.1186/s12872-023-03570-8.

Reference Type DERIVED
PMID: 38017432 (View on PubMed)

Other Identifiers

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1500170

Identifier Type: -

Identifier Source: org_study_id

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