Trial Outcomes & Findings for An Extended-Release Form of Clonidine as an Anti-Manic Agent: An Add-on, Open-Label Study (NCT NCT03065933)

NCT ID: NCT03065933

Last Updated: 2017-04-26

Results Overview

Mania rating scale to be performed each day of this 3 day study.

Recruitment status

TERMINATED

Study phase

PHASE4

Target enrollment

5 participants

Primary outcome timeframe

3 days

Results posted on

2017-04-26

Participant Flow

Participant milestones

Participant milestones
Measure
Clonidine as an Antimanic Agent
Subjects with Bipolar Disorder, Mania receive an extended-release form of clonidine on the second day of this 3-day study. Rating scales, record of sleep, and a questionnaire of adverse effects is recorded on each of the three days. extended-release clonidine: Subjects will received 0.2 mg extended-release clonidine twice on second day of this three-day study.
Overall Study
STARTED
5
Overall Study
COMPLETED
0
Overall Study
NOT COMPLETED
5

Reasons for withdrawal

Reasons for withdrawal
Measure
Clonidine as an Antimanic Agent
Subjects with Bipolar Disorder, Mania receive an extended-release form of clonidine on the second day of this 3-day study. Rating scales, record of sleep, and a questionnaire of adverse effects is recorded on each of the three days. extended-release clonidine: Subjects will received 0.2 mg extended-release clonidine twice on second day of this three-day study.
Overall Study
study terminated
5

Baseline Characteristics

No data was collected on the 5 participants, except for region of enrollment, before the study terminated.

Baseline characteristics by cohort

Baseline characteristics by cohort
Measure
Clonidine as an Antimanic Agent
n=5 Participants
Subjects with Bipolar Disorder, Mania receive an extended-release form of clonidine on the second day of this 3-day study. Rating scales, record of sleep, and a questionnaire of adverse effects is recorded on each of the three days. extended-release clonidine: Subjects will received 0.2 mg extended-release clonidine twice on second day of this three-day study.
Region of Enrollment
United States
5 Participants
n=5 Participants • All participants were enrolled in the United States, but no other data was collected.

PRIMARY outcome

Timeframe: 3 days

Population: No data was collected on the 5 participants, except for region of enrollment, before the study terminated.

Mania rating scale to be performed each day of this 3 day study.

Outcome measures

Outcome data not reported

Adverse Events

Clonidine as an Antimanic Agent

Serious events: 0 serious events
Other events: 0 other events
Deaths: 0 deaths

Serious adverse events

Adverse event data not reported

Other adverse events

Adverse event data not reported

Additional Information

Elizabeth S. Liebson, M.D.

McLean Hospital

Phone: 617-855-2284

Results disclosure agreements

  • Principal investigator is a sponsor employee
  • Publication restrictions are in place