Trial Outcomes & Findings for Tear Film Innovations iLux Safety Study (NCT NCT03055897)

NCT ID: NCT03055897

Last Updated: 2023-04-12

Results Overview

Post-heating values were obtained by infrared camera for each participant. The cornea, the eyelid, and the surface tissue surrounding the eye were measured. Both eyes contributed to the analysis. No formal hypothesis testing was specified.

Recruitment status

COMPLETED

Study phase

NA

Target enrollment

15 participants

Primary outcome timeframe

Day 0 immediately post-treatment

Results posted on

2023-04-12

Participant Flow

Participants were recruited from one investigative site located in the United States.

This reporting group includes all enrolled participants.

Participant milestones

Participant milestones
Measure
iLux 2020 System
Meibomian gland treatment (Day 0) according to instructions for use (IFU)/User Manual
Overall Study
STARTED
15
Overall Study
COMPLETED
15
Overall Study
NOT COMPLETED
0

Reasons for withdrawal

Withdrawal data not reported

Baseline Characteristics

Tear Film Innovations iLux Safety Study

Baseline characteristics by cohort

Baseline characteristics by cohort
Measure
iLux 2020 System
n=15 Participants
Meibomian gland treatment (Day 0) according to instructions for use (IFU)/User Manual
Age, Continuous
39.9 years
STANDARD_DEVIATION 15.1 • n=5 Participants
Sex/Gender, Customized
Male
7 participants
n=5 Participants
Sex/Gender, Customized
Not reported
8 participants
n=5 Participants
Race/Ethnicity, Customized
Hispanic/Latino
1 participants
n=5 Participants
Race/Ethnicity, Customized
White
11 participants
n=5 Participants
Race/Ethnicity, Customized
Not Reported
3 participants
n=5 Participants
Region of Enrollment
United States
15 participants
n=5 Participants

PRIMARY outcome

Timeframe: Day 0 immediately post-treatment

Population: Safety Analysis Set: All subjects enrolled and treated

Post-heating values were obtained by infrared camera for each participant. The cornea, the eyelid, and the surface tissue surrounding the eye were measured. Both eyes contributed to the analysis. No formal hypothesis testing was specified.

Outcome measures

Outcome measures
Measure
iLux 2020 System
n=30 eyes
Meibomian gland treatment (Day 0) according to instructions for use (IFU)/User Manual
Mean Overall Maximum Temperature of the Cornea and Surrounding Eye Tissue Immediately Post-treatment
Corneal temperature
37.7 degrees Celsius
Standard Deviation 0.5
Mean Overall Maximum Temperature of the Cornea and Surrounding Eye Tissue Immediately Post-treatment
Eyelid temperature
38.5 degrees Celsius
Standard Deviation 0.8
Mean Overall Maximum Temperature of the Cornea and Surrounding Eye Tissue Immediately Post-treatment
Surface temperature
38.2 degrees Celsius
Standard Deviation 0.7

Adverse Events

iLux 2020 System

Serious events: 0 serious events
Other events: 0 other events
Deaths: 0 deaths

Serious adverse events

Adverse event data not reported

Other adverse events

Adverse event data not reported

Additional Information

Senior CDMA Project Lead, CDMA Ocular Health

Alcon Research, LLC

Phone: 1-888-451-3937

Results disclosure agreements

  • Principal investigator is a sponsor employee
  • Publication restrictions are in place

Restriction type: OTHER