Cognitive Function Before and After Opioid Reduction in Patients With Chronic Pain
NCT ID: NCT03036917
Last Updated: 2019-07-05
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.
COMPLETED
50 participants
OBSERVATIONAL
2018-01-01
2019-05-03
Brief Summary
Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.
The patients will be tested before, halfway through, and after the programme.
Related Clinical Trials
Explore similar clinical trials based on study characteristics and research focus.
Cognitive Function and Addiction Under Opioid Tapering
NCT03365817
Identification of Predictive Markers of the Effects of Opioid Therapy in Patients With Chronic Pain.
NCT03701672
Attention and Memory Disorders Related to Acute Morphine
NCT03507985
The Immune and Endocrine Systems in Chronic Non-cancer Patients Treated With Opioids
NCT02277080
Experimental Medicine Study to Validate Pharmacodynamic Pain Assessments in Healthy Volunteers With an Opioid Analgesic (Remifentanil)
NCT02602002
Detailed Description
Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.
This leads to enormous costs, both human and economic. Many patients lose their ability to work, not only because of the pain, but also because of their treatment.
For a long period, opioids have been prescribed for chronic pain, even though the evidence is scarce.
A rising conscience about opioid use is on the way, and now, there is a tendency to reduce, rather than increase opioids.
The reasons are many: Constipation, inability to drive, a sense of drowsiness and no relief of pain, just to name a few. Furthermore, opioids may have decreased effect over time or may even lead to higher levels of pain.
Many patients are at first reluctant to start the reduction programme. Mostly because the patients may not be aware of the effects, the drugs are having on them. Many patients value their opioid treatment as positive and necessary, in spite of the many adverse effects.
The investigators wanted to test the cognitive function of patients before, during and after opioid reduction. The results can be used to help patients understand the deleterious effects of high opioid usage, and can also be used to motivate the individual patient along the way.
Conditions
See the medical conditions and disease areas that this research is targeting or investigating.
Study Design
Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.
COHORT
PROSPECTIVE
Eligibility Criteria
Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.
Inclusion Criteria
* Participating in the opioid reduction programme
Exclusion Criteria
* Patients suffering from dementia or psychosis
18 Years
ALL
No
Sponsors
Meet the organizations funding or collaborating on the study and learn about their roles.
Zealand University Hospital
OTHER
Responsible Party
Identify the individual or organization who holds primary responsibility for the study information submitted to regulators.
Principal Investigators
Learn about the lead researchers overseeing the trial and their institutional affiliations.
Stine Estrup, MD
Role: PRINCIPAL_INVESTIGATOR
Zealand University Hospital
Locations
Explore where the study is taking place and check the recruitment status at each participating site.
Holbæk Hospital
Holbæk, , Denmark
Zealand University Hospital
Køge, , Denmark
Countries
Review the countries where the study has at least one active or historical site.
Other Identifiers
Review additional registry numbers or institutional identifiers associated with this trial.
SE-4-2016
Identifier Type: -
Identifier Source: org_study_id
More Related Trials
Additional clinical trials that may be relevant based on similarity analysis.