Patient's Feelings After Receiving a Diagnosis of Age-related Macular Degeneration

NCT ID: NCT03035461

Last Updated: 2020-08-04

Basic Information

• Recruitment Status: COMPLETED
• Total Enrollment: 250 participants
• Study Classification: OBSERVATIONAL
• Study Start Date: 2017-03-15
• Study Completion Date: 2018-10-19

Brief Summary

Age-related macular degeneration (AMD) is the leading cause of blindness in the elderly population of the industrialized world. AMD is a progressive degenerative disease affecting the central area of the retina, responsible for distinct vision. Vision loss arises from aberrant new vessel growth which causes the accumulation of blood or fluid within the retina's thickness and eventually leads to permanent scarring. The two major forms of AMD are exudative, or neovascular or "wet", and non-exudative, or "dry".

Vascular endothelial growth factor (VEGF) represents the key modulator of the angiogenetic process and is involved in the pathophysiology of AMD. Anti VEGF therapies are used to treat wet-AMD.

After diagnosis and explanations of the practionner, the patients and their close relatives have still frequently many questions about the intravitreal injections, the prognosis, the risk of visual impairment, etc. Few teams have studied the modalities of diagnosis announcement and the understanding of the patients on the disease course.

The aim of this study is to evaluate the feelings after the AMD diagnosis announcement as well as the understanding of the possibilities of treatment and the clinical surveillance.

Conditions

Age Related Macular Degeneration

Study Design

• Observational Model Type: COHORT
• Study Time Perspective: PROSPECTIVE

Eligibility Criteria

Inclusion Criteria

• patient up to 55 years old
• wet AMD
• diagnostic questionnaire group: patient being announced with AMD for less than 1 month
• disease course questionnaire group: patients treated by anti-VEGF from 6 to 12 months

Exclusion Criteria

• dry AMD
• patient under 55 years old
• patient who doesn't speak French
• patient carrying an ophtalmologic genetic disorder

• Minimum Eligible Age: 55 Years
• Eligible Sex: ALL
• Accepts Healthy Volunteers: Yes

Sponsors

Centre Hospitalier Intercommunal Creteil

OTHER

Sponsor Role: lead

Responsible Party

Joëlle Marciano

Orthoptist in the ophtalmologic department of the CHI Creteil

Responsibility Role: PRINCIPAL_INVESTIGATOR

Locations

Marciano Joelle

Créteil, Creteil, France

Countries

France

Other Identifiers

PANDA

Identifier Type: -

Identifier Source: org_study_id