Brief Guided Relaxation for Women Undergoing Stereotactic Breast Biopsy

NCT ID: NCT03023215

Last Updated: 2023-09-07

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

84 participants

Study Classification

INTERVENTIONAL

Study Start Date

2012-10-26

Study Completion Date

2022-08-10

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

The goal of this behavioral research study is to learn if taking part in guided relaxation programs helps to reduce anxiety and pain during stereotactic breast biopsy. The study will also examine whether the guided relaxation programs change brain activity, heart rate, and blood pressure.

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

Baseline Data Collection:

If participant chooses to take part in this study, they will be asked to fill out several questionnaires on an MD Anderson computer. Participant will be asked questions about anxiety, pain, and spirituality. The questionnaires will take about 20 minutes to complete.

Participant will have their heart rate and blood pressure taken, which will take about 3 minutes to complete. Participant will then have an electroencephalogram (EEG) done. An EEG is used to view a person's brain waves. The EEG should take about 5 minutes to complete. During the EEG, a snug cap which contains small electrodes will be placed on the head to measure the electrical patterns coming from the brain--much like the way a doctor listens to participant's heart from the surface of their skin. The EEG cap will stay on participant's head until the end of the study.

Study Groups:

After the baseline information is collected, participant will be randomly assigned (as in the role of a die) to 1 of 3 study groups: 2 relaxation training groups or a standard care group. Based on the way the study is designed, there is a 1 in 5 (or 20%) chance that participant will be assigned to the standard care group, and a 4 in 5 (or 80%) chance that participant will be assigned to one of the relaxation groups. Both relaxation groups will focus on helping participant to relax by focusing on their breath. At the end of participation, all groups will be given a 25 minute relaxation audio CD created by the MD Anderson Integrative Medicine Program.

Pre-Breast Biopsy Procedures:

Participants assigned to the relaxation groups will be guided through relaxation techniques for 10 minutes before the biopsy. Participants assigned to the third group will listen to 10 minutes of National Public Radio.

Participant's heart rate and EEG activity will be recorded during this 10-minute period of time. At the end of the 10-minute period before the breast biopsy, participant's blood pressure will be taken again and they will complete a 5 minute questionnaire about anxiety.

Breast Biopsy Procedures:

When it is time for the biopsy procedure, the research assistant will go with participant to their procedure room. In the procedure room, the research assistant will continue to monitor participant's heart rate and EEG activity throughout the biopsy time. If participant is in one of the relaxation groups, the relaxation guide will also accompany participant to the procedure room and will continue to be guided through relaxation during the biopsy procedure. If participant is in the standard care group, they will be provided with the usual breast biopsy care. Participant will be asked to talk about any anxiety and pain at several times during the procedure. Participant will also be asked to rest with their eyes closed during the biopsy procedure.

After the biopsy is finished, the research assistant will go with participant to a separate room, and they will have 5 minutes of EEG activity recorded, and their blood pressure will be taken. The EEG cap will then be removed, and participant will be asked to complete a questionnaire about their experience that will take less than 10 minutes to complete.

This is an investigational study.

Up to 85 participants will take part in this study. All will be enrolled at MD Anderson.

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Meditation for Breast Biopsy

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

SINGLE

Participants

Study Groups

Review each arm or cohort in the study, along with the interventions and objectives associated with them.

Guided Meditation Group (GM)

Participants guided through 10 minutes of intervention by a mind-body specialist who will follow a standardized script prior to stereotactic breast biopsy (SBB). Mind-body specialist will also accompany participant during SBB to continue intervention.

Electroencephalogram (EEG) activity and heart rate (HR) recorded at baseline, for 10 minutes prior to the SBB, throughout the SBB, and immediately following SBB.

Self-report measures (anxiety and pain) assessed at baseline, immediately before, during, and after the SBB.

Group Type EXPERIMENTAL

Meditation

Intervention Type PROCEDURE

Participants guided through 10 minutes of intervention by a mind-body specialist who will follow a standardized script prior to stereotactic breast biopsy (SBB). Mind-body specialist will also accompany participant during SBB to continue intervention.

Electroencephalogram

Intervention Type PROCEDURE

Electroencephalogram (EEG) activity recorded at baseline, for 10 minutes prior to the SBB, throughout the SBB, and immediately following SBB.

Questionnaires

Intervention Type BEHAVIORAL

Self-report measures (anxiety and pain) assessed at baseline, immediately before, during, and after the SBB.

Heart Rate

Intervention Type PROCEDURE

Heart rate (HR) recorded at baseline, for 10 minutes prior to the SBB, throughout the SBB, and immediately following SBB.

Focused Breathing Group (FB)

Participants guided through 10 minutes of intervention by a mind-body specialist who will follow a standardized script prior to stereotactic breast biopsy (SBB). Mind-body specialist will also accompany participant during SBB to continue intervention.

Electroencephalogram (EEG) activity and heart rate (HR) recorded at baseline, for 10 minutes prior to the SBB, throughout the SBB, and immediately following SBB.

Self-report measures (anxiety and pain) assessed at baseline, immediately before, during, and after the SBB..

Group Type ACTIVE_COMPARATOR

Meditation

Intervention Type PROCEDURE

Participants guided through 10 minutes of intervention by a mind-body specialist who will follow a standardized script prior to stereotactic breast biopsy (SBB). Mind-body specialist will also accompany participant during SBB to continue intervention.

Electroencephalogram

Intervention Type PROCEDURE

Electroencephalogram (EEG) activity recorded at baseline, for 10 minutes prior to the SBB, throughout the SBB, and immediately following SBB.

Questionnaires

Intervention Type BEHAVIORAL

Self-report measures (anxiety and pain) assessed at baseline, immediately before, during, and after the SBB.

Heart Rate

Intervention Type PROCEDURE

Heart rate (HR) recorded at baseline, for 10 minutes prior to the SBB, throughout the SBB, and immediately following SBB.

Standard of Care Group (SC)

Participants listen to a 10 minute neutral-content audio clip from National Public Radio prior to stereotactic breast biopsy (SBB).

Electroencephalogram (EEG) activity and heart rate (HR) recorded at baseline, for 10 minutes prior to the SBB, throughout the SBB, and immediately following SBB.

Self-report measures (anxiety and pain) assessed at baseline, immediately before, during, and after the SBB.

Group Type ACTIVE_COMPARATOR

Electroencephalogram

Intervention Type PROCEDURE

Electroencephalogram (EEG) activity recorded at baseline, for 10 minutes prior to the SBB, throughout the SBB, and immediately following SBB.

Questionnaires

Intervention Type BEHAVIORAL

Self-report measures (anxiety and pain) assessed at baseline, immediately before, during, and after the SBB.

Heart Rate

Intervention Type PROCEDURE

Heart rate (HR) recorded at baseline, for 10 minutes prior to the SBB, throughout the SBB, and immediately following SBB.

Interventions

Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.

Meditation

Participants guided through 10 minutes of intervention by a mind-body specialist who will follow a standardized script prior to stereotactic breast biopsy (SBB). Mind-body specialist will also accompany participant during SBB to continue intervention.

Intervention Type PROCEDURE

Electroencephalogram

Electroencephalogram (EEG) activity recorded at baseline, for 10 minutes prior to the SBB, throughout the SBB, and immediately following SBB.

Intervention Type PROCEDURE

Questionnaires

Self-report measures (anxiety and pain) assessed at baseline, immediately before, during, and after the SBB.

Intervention Type BEHAVIORAL

Heart Rate

Heart rate (HR) recorded at baseline, for 10 minutes prior to the SBB, throughout the SBB, and immediately following SBB.

Intervention Type PROCEDURE

Other Intervention Names

Discover alternative or legacy names that may be used to describe the listed interventions across different sources.

EEG Surveys HR

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

1. Women must have the ability to understand and read English, sign a written informed consent, and be willing to follow protocol requirements.
2. Women must be right hand dominant.
3. Women must be 18 years or older.

Exclusion Criteria

1. Women who have a documented diagnosis of a formal thought disorder (e.g., schizophrenia) will be excluded from the study.
2. Women with a score of 3 or below on the Six-Item Cognitive Screener.
3. Women who plan to take benzodiazepine (e.g, alprazolam, diazepam, clonazepam, lorazepam) or beta-blocker (e.g., propranolol, atenolol) on the day of their SBB.
Minimum Eligible Age

18 Years

Eligible Sex

FEMALE

Accepts Healthy Volunteers

No

Sponsors

Meet the organizations funding or collaborating on the study and learn about their roles.

M.D. Anderson Cancer Center

OTHER

Sponsor Role lead

Responsible Party

Identify the individual or organization who holds primary responsibility for the study information submitted to regulators.

Responsibility Role SPONSOR

Principal Investigators

Learn about the lead researchers overseeing the trial and their institutional affiliations.

Lorenzo Cohen, PHD

Role: PRINCIPAL_INVESTIGATOR

M.D. Anderson Cancer Center

Locations

Explore where the study is taking place and check the recruitment status at each participating site.

University of Texas MD Anderson Cancer Center

Houston, Texas, United States

Site Status

Countries

Review the countries where the study has at least one active or historical site.

United States

Related Links

Access external resources that provide additional context or updates about the study.

http://www.mdanderson.org

University of Texas MD Anderson Cancer Center Website

Other Identifiers

Review additional registry numbers or institutional identifiers associated with this trial.

NCI-2017-00506

Identifier Type: OTHER

Identifier Source: secondary_id

2011-1094

Identifier Type: -

Identifier Source: org_study_id

More Related Trials

Additional clinical trials that may be relevant based on similarity analysis.