Trial Outcomes & Findings for Pragmatic, Randomized Evaluation of Statin Active Choice to Reach Improved Outcomes Based on Evidence (NCT NCT03021759)

NCT ID: NCT03021759

Last Updated: 2019-06-20

Results Overview

Percentage of patients eligible for a statin that have been prescribed a statin

Recruitment status

COMPLETED

Study phase

NA

Target enrollment

4774 participants

Primary outcome timeframe

Two Months

Results posted on

2019-06-20

Participant Flow

No informed consent was obtained from the participants in this study.

Participant milestones

Participant milestones
Measure
Control
No intervention
Active Choice
Physicians will be asked to review a list of their patients eligible for statin therapy who are not yet prescribed a statin and make an active choice whether or not to prescribe a statin. Active choice: Statin options are framed to physicians as an active choice to prescribe or not prescribe a statin
Active Choice With Social Comparison Feedback
Physicians will be asked to review a list of their patients eligible for statin therapy who are not yet prescribed a statin and make an active choice whether or not to prescribe a statin. Physicians will receive social comparison feedback informing them of how their performance compares to their peers Active choice: Statin options are framed to physicians as an active choice to prescribe or not prescribe a statin. Social comparison feedback: Statin prescribing rates are communicated to physicians and along with how their performance compares to their peers
Overall Study
STARTED
1566
1743
1465
Overall Study
COMPLETED
1566
1743
1465
Overall Study
NOT COMPLETED
0
0
0

Reasons for withdrawal

Withdrawal data not reported

Baseline Characteristics

Pragmatic, Randomized Evaluation of Statin Active Choice to Reach Improved Outcomes Based on Evidence

Baseline characteristics by cohort

Baseline characteristics by cohort
Measure
Control
n=1566 Participants
No intervention
Active Choice
n=1743 Participants
Physicians will be asked to review a list of their patients eligible for statin therapy who are not yet prescribed a statin and make an active choice whether or not to prescribe a statin. Active choice: Statin options are framed to physicians as an active choice to prescribe or not prescribe a statin
Active Choice With Social Comparison Feedback
n=1465 Participants
Physicians will be asked to review a list of their patients eligible for statin therapy who are not yet prescribed a statin and make an active choice whether or not to prescribe a statin. Physicians will receive social comparison feedback informing them of how their performance compares to their peers Active choice: Statin options are framed to physicians as an active choice to prescribe or not prescribe a statin Social comparison feedback: Statin prescribing rates are communicated to physicians and along with how their performance compares to their peers
Total
n=4774 Participants
Total of all reporting groups
Age, Continuous
62.1 years
STANDARD_DEVIATION 8.5 • n=5 Participants
62.4 years
STANDARD_DEVIATION 8.2 • n=7 Participants
62.5 years
STANDARD_DEVIATION 8.2 • n=5 Participants
62.4 years
STANDARD_DEVIATION 8.3 • n=4 Participants
Sex: Female, Male
Female
738 Participants
n=5 Participants
710 Participants
n=7 Participants
701 Participants
n=5 Participants
2149 Participants
n=4 Participants
Sex: Female, Male
Male
828 Participants
n=5 Participants
1033 Participants
n=7 Participants
764 Participants
n=5 Participants
2625 Participants
n=4 Participants
Race/Ethnicity, Customized
White non-Hispanic
1004 Participants
n=5 Participants
1110 Participants
n=7 Participants
926 Participants
n=5 Participants
3040 Participants
n=4 Participants
Race/Ethnicity, Customized
Black non-Hispanic
420 Participants
n=5 Participants
479 Participants
n=7 Participants
419 Participants
n=5 Participants
1318 Participants
n=4 Participants
Race/Ethnicity, Customized
Other
142 Participants
n=5 Participants
154 Participants
n=7 Participants
120 Participants
n=5 Participants
416 Participants
n=4 Participants
Annual Household Income
<50,000 US$
435 Participants
n=5 Participants
563 Participants
n=7 Participants
406 Participants
n=5 Participants
1404 Participants
n=4 Participants
Annual Household Income
50,000 - 100,000 US$
784 Participants
n=5 Participants
960 Participants
n=7 Participants
733 Participants
n=5 Participants
2477 Participants
n=4 Participants
Annual Household Income
>100,000 US$
341 Participants
n=5 Participants
206 Participants
n=7 Participants
312 Participants
n=5 Participants
859 Participants
n=4 Participants
Annual Household Income
Missing
6 Participants
n=5 Participants
14 Participants
n=7 Participants
14 Participants
n=5 Participants
34 Participants
n=4 Participants

PRIMARY outcome

Timeframe: Two Months

Percentage of patients eligible for a statin that have been prescribed a statin

Outcome measures

Outcome measures
Measure
Control
n=1566 Participants
No intervention
Active Choice
n=1743 Participants
Physicians will be asked to review a list of their patients eligible for statin therapy who are not yet prescribed a statin and make an active choice whether or not to prescribe a statin. Active choice: Statin options are framed to physicians as an active choice to prescribe or not prescribe a statin
Active Choice With Social Comparison Feedback
n=1465 Participants
Physicians will be asked to review a list of their patients eligible for statin therapy who are not yet prescribed a statin and make an active choice whether or not to prescribe a statin. Physicians will receive social comparison feedback informing them of how their performance compares to their peers Active choice: Statin options are framed to physicians as an active choice to prescribe or not prescribe a statin Social comparison feedback: Statin prescribing rates are communicated to physicians and along with how their performance compares to their peers
Statin Prescribing Rate
40 Participants
116 Participants
117 Participants

Adverse Events

Control

Serious events: 0 serious events
Other events: 0 other events
Deaths: 0 deaths

Active Choice

Serious events: 0 serious events
Other events: 0 other events
Deaths: 0 deaths

Active Choice With Social Comparison Feedback

Serious events: 0 serious events
Other events: 0 other events
Deaths: 0 deaths

Serious adverse events

Adverse event data not reported

Other adverse events

Adverse event data not reported

Additional Information

Rebecca Pepe

University of Pennsylvania

Phone: 215-360-0951

Results disclosure agreements

  • Principal investigator is a sponsor employee
  • Publication restrictions are in place