Trial Outcomes & Findings for Clinical and Radiological Evaluation of Patients With DDD Following TLIF With 3-D Printed Titanium Cage (NCT NCT03018392)

NCT ID: NCT03018392

Last Updated: 2022-09-07

Results Overview

Fusion status at 1 year post-operatively was graded as - fused (best outcome), progressing, or pseudoarthrosis (failed fusion)

Recruitment status

COMPLETED

Study phase

NA

Target enrollment

20 participants

Primary outcome timeframe

1 year

Results posted on

2022-09-07

Participant Flow

Participant milestones

Participant milestones
Measure
Tritanium
TLIF with Tritanium® PL cage and pedicle screw fixation Stryker Tritanium Spinal System: open transforaminal lumbar interbody fusion (TLIF) utilizing the Stryker Tritanium cages with pedicle screw fixation according to instructions for use and package labeling for on-label indications
Overall Study
STARTED
20
Overall Study
COMPLETED
20
Overall Study
NOT COMPLETED
0

Reasons for withdrawal

Withdrawal data not reported

Baseline Characteristics

Race and Ethnicity were not collected from any participant.

Baseline characteristics by cohort

Baseline characteristics by cohort
Measure
Tritanium
n=20 Participants
TLIF with Tritanium® PL cage and pedicle screw fixation Stryker Tritanium Spinal System: open transforaminal lumbar interbody fusion (TLIF) utilizing the Stryker Tritanium cages with pedicle screw fixation according to instructions for use and package labeling for on-label indications
Age, Continuous
67.5 years
STANDARD_DEVIATION 7.8 • n=20 Participants
Sex: Female, Male
Female
9 Participants
n=20 Participants
Sex: Female, Male
Male
11 Participants
n=20 Participants
BMI
31.6 kg/m^2
STANDARD_DEVIATION 4 • n=20 Participants

PRIMARY outcome

Timeframe: 1 year

Fusion status at 1 year post-operatively was graded as - fused (best outcome), progressing, or pseudoarthrosis (failed fusion)

Outcome measures

Outcome measures
Measure
Tritanium
n=20 Participants
TLIF with Tritanium® PL cage and pedicle screw fixation Stryker Tritanium Spinal System: open transforaminal lumbar interbody fusion (TLIF) utilizing the Stryker Tritanium cages with pedicle screw fixation according to instructions for use and package labeling for on-label indications
Fusion Rate
Pseudoarthrosis
1 Participants
Fusion Rate
Fused
19 Participants
Fusion Rate
Progressing
0 Participants

Adverse Events

Tritanium

Serious events: 1 serious events
Other events: 1 other events
Deaths: 0 deaths

Serious adverse events

Serious adverse events
Measure
Tritanium
n=20 participants at risk
TLIF with Tritanium® PL cage and pedicle screw fixation Stryker Tritanium Spinal System: open transforaminal lumbar interbody fusion (TLIF) utilizing the Stryker Tritanium cages with pedicle screw fixation according to instructions for use and package labeling for on-label indications
Surgical and medical procedures
Extension of fusion
5.0%
1/20 • Number of events 1 • 1 year

Other adverse events

Other adverse events
Measure
Tritanium
n=20 participants at risk
TLIF with Tritanium® PL cage and pedicle screw fixation Stryker Tritanium Spinal System: open transforaminal lumbar interbody fusion (TLIF) utilizing the Stryker Tritanium cages with pedicle screw fixation according to instructions for use and package labeling for on-label indications
Product Issues
Cage Fracture
5.0%
1/20 • Number of events 1 • 1 year

Additional Information

Research Projects Director

Bone and Joint Clinic of Baton Rouge

Phone: 2254218207

Results disclosure agreements

  • Principal investigator is a sponsor employee
  • Publication restrictions are in place

Restriction type: LTE60