Turmeric for Patients With Basal Joint Arthritis

NCT ID: NCT03017118

Last Updated: 2025-11-24

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Clinical Phase

NA

Total Enrollment

60 participants

Study Classification

INTERVENTIONAL

Study Start Date

2017-08-09

Study Completion Date

2028-01-31

Brief Summary

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The aim of this study is to assess whether the use of a commercially available nutraceutical, turmeric, is an effective option to manage pain and stiffness in patients with basal joint arthritis. To conduct a pilot Randomized Controlled Trial evaluating the impact of turmeric on basal joint arthritis.

Detailed Description

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Conditions

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Thumb Osteoarthritis

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

QUADRUPLE

Participants Caregivers Investigators Outcome Assessors

Study Groups

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Turmeric

Subjects in this group will receive turmeric (100 mg pastille) 3 times per day for 6 weeks.

Group Type EXPERIMENTAL

Turmeric

Intervention Type DIETARY_SUPPLEMENT

Subjects will receive turmeric (100 mg pastille) 3 times per day for 6 weeks.

Control

Subjects in this group will receive a placebo pill 3 times per day for 6 weeks.

Group Type PLACEBO_COMPARATOR

Placebo

Intervention Type OTHER

Subjects in the control group will receive a placebo 3 times per day for 6 weeks.

Interventions

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Turmeric

Subjects will receive turmeric (100 mg pastille) 3 times per day for 6 weeks.

Intervention Type DIETARY_SUPPLEMENT

Placebo

Subjects in the control group will receive a placebo 3 times per day for 6 weeks.

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* 40 years of age or older
* English fluency and literacy
* Seeking care for basal joint pain
* Tender over basal joint
* Positive distraction rotation test (rotation of the thumb metacarpal base while applying axial traction)
* Radiographic evidence of Eaton stage 1 and 2 only

Exclusion Criteria

* Secondary gains (litigations or worker compensation) procedures that may interfere with patients' motivation for treatment
* Inability or unwillingness to participate in a trial study
* Rheumatoid Arthritis or other inflammatory disorder diagnoses
* Post-traumatic osteoarthritis
* Patients on Coumadin/Steroids/NSAIDs/Tylenol
* Diabetes Mellitus
* Pregnant or lactating women
* Basal joint arthritis of Eaton stage 3
* Patients seeking other treatment for their basal joint arthritis (splint, corticosteroid injection, surgery)
Minimum Eligible Age

40 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Massachusetts General Hospital

OTHER

Sponsor Role lead

Responsible Party

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Neal Chung-Jen Chen

Medical Doctor

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Neal Chen, MD

Role: PRINCIPAL_INVESTIGATOR

Massachusetts General Hospital

Locations

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Massachusetts General Hospital

Boston, Massachusetts, United States

Site Status RECRUITING

Countries

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United States

Central Contacts

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Neal Chen, M.D.

Role: CONTACT

617-726-4700

Karan Amin, BA

Role: CONTACT

Facility Contacts

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Neal Chen, MD

Role: primary

617-726-4700

Kiera Lunn, BSc

Role: backup

6177261569

Other Identifiers

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2016P001402

Identifier Type: -

Identifier Source: org_study_id

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