The Effects of WBV on Muscle Stiffness and Reflex Activity in Stroke.
NCT ID: NCT03015545
Last Updated: 2018-12-10
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
NA
36 participants
INTERVENTIONAL
2017-05-01
2017-12-31
Brief Summary
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Detailed Description
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Purpose This study aims to investigate the acute effect of WBV on leg muscle H-reflex, stiffness and blood perfusion in people with chronic stroke.
Methods Individuals with chronic stroke will be recruited from community self-help groups and existing patient database. Relevant information (e.g. demographic information, medical history) will be obtained from medical records and subject interviews. Each subject will have to fulfill the following inclusion criteria: (1) diagnosis of chronic stroke, (2) community-dwelling, (3) able to follow simple verbal instructions. Exclusion criteria are: (1) other diagnoses of neurological conditions, (2) significant musculoskeletal conditions (e.g. amputations), (3) metal implants in the lower extremity or spine, (4) recent fracture in the lower extremity, (5) diagnosis of osteoporosis, (6) vestibular disorders, (7) peripheral vascular disease, and (11) other serious illnesses or contraindications to exercise.
This is a single-blinded randomized within-patient cross-over study. Each participant was evaluated for the soleus H-reflex, stiffness and blood perfusion of the medial gastrocnemius (MG) using ultrasound on both sides before and after either a 5-minute WBV intervention (30 Hertz, 1.5mm, knee flexed 60 degrees) or a no-WBV condition (5 minutes). The measurements were performed at baseline and every 1-min post-intervention up to 5 minutes. The outcomes generated included the soleus H/M ratio, shear modulus and vascular index (VI) of the MG muscle.
Conditions
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Keywords
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Study Design
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RANDOMIZED
CROSSOVER
TREATMENT
SINGLE
Study Groups
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Control
This group will stand with knee flexion 60 degrees on the same vibration platform for 60 seconds for 5 times with 60-seconds rest interval, but no vibration will be given.
paretic leg-control
standing on the vibration platform, with no vibration signals delivered.
non-paretic leg-control
standing on the vibration platform, with no vibration signals delivered.
High intensity whole body vibration
This group will stand with knee flexion 60 degrees on the same vibration platform for 60 seconds for 5 times with 60-seconds rest interval. The whole body vibration platform will be set with frequency at 30Hz and amplitude at 1.5mm.
paretic leg-WBV
standing on the vibration platform, with WBV at 30Hz, 1.5mm.
non-paretic leg-WBV
standing on the vibration platform, with WBV at 30Hz, 1.5mm.
Interventions
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paretic leg-control
standing on the vibration platform, with no vibration signals delivered.
paretic leg-WBV
standing on the vibration platform, with WBV at 30Hz, 1.5mm.
non-paretic leg-control
standing on the vibration platform, with no vibration signals delivered.
non-paretic leg-WBV
standing on the vibration platform, with WBV at 30Hz, 1.5mm.
Eligibility Criteria
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Inclusion Criteria
2. Medically stable,
3. Able to stand independently for at least 1 minute and
4. Mas score \>1 measured at the ankle plantar flexors.
Exclusion Criteria
2. Other neurological condition,
3. Serious musculoskeletal or cardiovascular disease,
4. Severe contracture of the ankle that the cannot be put in the neutral position.
5. Metal implants or recent fractures in the lower extremities or spine,
6. Fresh skin wound in lower extremities, especially popliteal fossa
7. Other severe illnesses or contraindication for exercise.
18 Years
ALL
No
Sponsors
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The Hong Kong Polytechnic University
OTHER
Responsible Party
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Marco Yiu-Chung Pang
Professor
Principal Investigators
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Hector WH Tsang, PhD
Role: STUDY_CHAIR
Department of Rehabilitation Sciences, The Hong Kong Polytechnic University
Locations
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The Hong Kong Polytechnic University
Hung Hom, Kowloon, Hong Kong
Countries
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Other Identifiers
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HSEARS20161117007
Identifier Type: -
Identifier Source: org_study_id