New Transporting Solution in Parathyroid Allotransplantation
NCT ID: NCT02978287
Last Updated: 2016-11-30
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.
UNKNOWN
NA
7 participants
INTERVENTIONAL
2016-09-30
2016-12-31
Brief Summary
Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.
Detailed Description
Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.
Calcium sensing receptor plays a crucial role in regulating Parathormone secretion which means controlling of the calcium-dependent systemic ion homeostasis.
The investigators developed a new tissue transporting solution for parathyroid allotransplantation and the investigators measured the parathyroid cell viability and the the amount of calcium sensing receptor of the parathyroid cells at the 0., 6., 12. and 24. hours of the parathyroid cells which were placed into our new solution.
Conditions
See the medical conditions and disease areas that this research is targeting or investigating.
Keywords
Explore important study keywords that can help with search, categorization, and topic discovery.
Study Design
Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.
NON_RANDOMIZED
SINGLE_GROUP
PREVENTION
NONE
Study Groups
Review each arm or cohort in the study, along with the interventions and objectives associated with them.
BAVU Solution 0. hour (control)
Viability, Calcium sensing receptor and parathormone levels of Parathyroid cells at 0. hour
No interventions assigned to this group
BAVU Solution 6. hour
Viability, Calcium sensing receptor and parathormone levels of Parathyroid cells at 6. hour
BAVU Solution
Tissue preservation solution for transplantation
BAVU Solution 12. hour
Viability, Calcium sensing receptor and parathormone levels of Parathyroid cells at 12. hour
BAVU Solution
Tissue preservation solution for transplantation
BAVU Solution 18. hour
Viability, Calcium sensing receptor and parathormone levels of Parathyroid cells at 18. hour
BAVU Solution
Tissue preservation solution for transplantation
BAVU Solution 24. hour
Viability, Calcium sensing receptor and parathormone levels of Parathyroid cells at 24. hour
BAVU Solution
Tissue preservation solution for transplantation
Interventions
Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.
BAVU Solution
Tissue preservation solution for transplantation
Eligibility Criteria
Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.
Inclusion Criteria
Exclusion Criteria
* Patients younger than 18 years and older than 80 years.
* Patients who have hepatitis B,
* Patients who have hepatitis C,
* Patients who have human immunodeficiency virus (HIV)
18 Years
80 Years
ALL
No
Sponsors
Meet the organizations funding or collaborating on the study and learn about their roles.
Bezmialem Vakif University
OTHER
Sisli Hamidiye Etfal Training and Research Hospital
OTHER
Responsible Party
Identify the individual or organization who holds primary responsibility for the study information submitted to regulators.
Ufuk Oguz Idiz
Principal Investigator
Locations
Explore where the study is taking place and check the recruitment status at each participating site.
Bezmialem University
Istanbul, , Turkey (Türkiye)
Countries
Review the countries where the study has at least one active or historical site.
Central Contacts
Reach out to these primary contacts for questions about participation or study logistics.
Facility Contacts
Find local site contact details for specific facilities participating in the trial.
Erhan Aysan, Prof M.D.
Role: primary
Ufuk Oguz Idiz, M.D.
Role: backup
References
Explore related publications, articles, or registry entries linked to this study.
Guibert EE, Petrenko AY, Balaban CL, Somov AY, Rodriguez JV, Fuller BJ. Organ Preservation: Current Concepts and New Strategies for the Next Decade. Transfus Med Hemother. 2011;38(2):125-142. doi: 10.1159/000327033. Epub 2011 Mar 21.
Hendy GN, Guarnieri V, Canaff L. Calcium-sensing receptor and associated diseases. Prog Mol Biol Transl Sci. 2009;89:31-95. doi: 10.1016/S1877-1173(09)89003-0. Epub 2009 Oct 7.
Voigt MR, DeLario GT. Perspectives on abdominal organ preservation solutions: a comparative literature review. Prog Transplant. 2013 Dec;23(4):383-91. doi: 10.7182/pit2013100.
Nawrot I, Wozniewicz B, Tolloczko T, Sawicki A, Gorski A, Chudzinski W, Wojtaszek M, Grzesiuk W, Sladowski D, Karwacki J, Zawitkowska T, Szmidt J. Allotransplantation of cultured parathyroid progenitor cells without immunosuppression: clinical results. Transplantation. 2007 Mar 27;83(6):734-40. doi: 10.1097/01.tp.0000258601.17505.9d.
Other Identifiers
Review additional registry numbers or institutional identifiers associated with this trial.
BAVU Solusyon
Identifier Type: -
Identifier Source: org_study_id