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Comparison of Inflammatory Responses Subsequent to Different Cesarean Section Techniques

NCT ID: NCT02976311

Last Updated: 2016-11-29

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

88 participants

Study Classification

INTERVENTIONAL

Study Start Date

2016-04-30

Study Completion Date

2016-09-30

Brief Summary

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In this study, the investigators aimed to find out whether there are any differences in inflammatory reactions occured subsequent to two different cesarean delivery techniques; modified Misgav-Ladach vs Pfannenstiel-Kerr techniques.

Detailed Description

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Cesarean section is one of the most undertaken operations in women of childbearing age. However, there is not a unique cesarean surgery technique. Pfannenstiel , reported his own technique in 1897. Because of the applicability of the technique, it went down well among obstetricians. After three decades, Kerr evolved this technique, and Pfannenstiel-Kerr technique became the method of choice until late 70's. In 1972, Stark et al defined the Misgav Ladach technique and in the following years this technique became popular among obstetricians. In late 80's Misgav Ladach technique was modified and started to be more popular. But, still Pfannenstiel-Kerr technique continued to be used frequently and studies comparing clinical outcomes of these two techniques were conducted for several times. However, the inflammatory responses which occured subsequent to application of these techniques were not investigated. This is the first study investigating the inflammatory response emerged after different cesarean surgery techniques.

Conditions

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Delivery Cesarean Delivery Inflammation

Keywords

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inflammatory reaction IL-6 TNF Misgav Ladach technique Pfannenstiel-Kerr technique cesarean delivery cesarean technique

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

DIAGNOSTIC

Blinding Strategy

SINGLE

Investigators

Study Groups

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Misgav-Ladach

cesarean section(C/S) via the modified 'Misgav-Ladach' technique

Group Type ACTIVE_COMPARATOR

cesarean section(C/S) via the modified Misgav-Ladach technique

Intervention Type PROCEDURE

the first consecutive 44 patients underwent C/S via the modified Misgav-Ladach technique

Pfannenstiel-Kerr

cesarean section(C/S) via the 'Pfannenstiel-Kerr' technique

Group Type ACTIVE_COMPARATOR

cesarean section via the Pfannenstiel-Kerr technique

Intervention Type PROCEDURE

the second consecutive 44 patients underwent C/S via the Pfannenstiel-Kerr technique

Interventions

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cesarean section(C/S) via the modified Misgav-Ladach technique

the first consecutive 44 patients underwent C/S via the modified Misgav-Ladach technique

Intervention Type PROCEDURE

cesarean section via the Pfannenstiel-Kerr technique

the second consecutive 44 patients underwent C/S via the Pfannenstiel-Kerr technique

Intervention Type PROCEDURE

Eligibility Criteria

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Inclusion Criteria

* Cesarean section for the first time
* Term,singleton pregnancy

Exclusion Criteria

* Any inflammatory disease
* Any pregnancy complication; IUGR,preeclampsia,preterm labor,preterm premature rupture of membranes
* Pregnancies \<37weeks gestational age
Minimum Eligible Age

18 Years

Maximum Eligible Age

35 Years

Eligible Sex

FEMALE

Accepts Healthy Volunteers

Yes

Sponsors

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Kayseri Education and Research Hospital

OTHER_GOV

Sponsor Role lead

Responsible Party

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Hatice Akkaya

doctor

Responsibility Role PRINCIPAL_INVESTIGATOR

Other Identifiers

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E52332816_51

Identifier Type: -

Identifier Source: org_study_id