Big Data Construction and Biological Etiological Epidemiology Study of Children Epilepsy in China

NCT ID: NCT02969213

Last Updated: 2016-11-21

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Total Enrollment

10000 participants

Study Classification

OBSERVATIONAL

Study Start Date

2016-11-30

Study Completion Date

2019-12-31

Brief Summary

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The purpose of this study is to develop the electronic management platform for children with epilepsy, establish large data of Chinese children with epilepsy and explore its biological etiology.

Detailed Description

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The establishment of the electronic management platform for children with epilepsy and large data of epilepsy in Chinese children as well as the epidemiological study its biological etiology.

Conditions

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Epilepsy

Keywords

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Electronic management of epilepsy biological etiology Chinese children

Study Design

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Study Time Perspective

RETROSPECTIVE

Study Groups

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Genetic

patients with Gene detection (+)

No interventions assigned to this group

Metabolism

patients with Metabolic disturbance

No interventions assigned to this group

Immune

patients with Immunological marker and Immunotherapy (+)

No interventions assigned to this group

infection

patients with the Infection of central nervous system

No interventions assigned to this group

structure

patients with abnormal image of brain

No interventions assigned to this group

unknown

patients not found any reason

No interventions assigned to this group

Eligibility Criteria

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Inclusion Criteria

* Children with epilepsy diagnosis, seizure types and causes of disease classification in accordance with the International Association for the diagnosis and treatment of epilepsy in 2015 guidelines
* Epilepsy children Included 0-14 years old from outpatients and inpatients by the Children's epilepsy specialist using iGrowSys management platform and clinical research, and medical records data entry complete in all China

Exclusion Criteria

* The patients that recorded data is not complete, telephone and communication address unknown
* The patients that families do not have Internet or children and families will not access the Internet, can not be online operation
Maximum Eligible Age

14 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Xinhua Hospital, Shanghai Jiao Tong University School of Medicine

OTHER

Sponsor Role lead

Responsible Party

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Ling Li

chief physician,proffessor

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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Ling Li

Shanghai, , China

Site Status

Countries

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China

Facility Contacts

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Ling Li, PhD

Role: primary

Mei Yu Yan, PhD

Role: backup

References

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Sauro KM, Wiebe S, Dunkley C, Janszky J, Kumlien E, Moshe S, Nakasato N, Pedley TA, Perucca E, Senties H, Thomas SV, Wang Y, Wilmshurst J, Jette N. The current state of epilepsy guidelines: A systematic review. Epilepsia. 2016 Jan;57(1):13-23. doi: 10.1111/epi.13273. Epub 2015 Dec 10.

Reference Type BACKGROUND
PMID: 26659723 (View on PubMed)

Singh A, Trevick S. The Epidemiology of Global Epilepsy. Neurol Clin. 2016 Nov;34(4):837-847. doi: 10.1016/j.ncl.2016.06.015.

Reference Type RESULT
PMID: 27719996 (View on PubMed)

Lua PL, Neni WS. Health-related quality of life improvement via telemedicine for epilepsy: printed versus SMS-based education intervention. Qual Life Res. 2013 Oct;22(8):2123-32. doi: 10.1007/s11136-013-0352-6. Epub 2013 Jan 18.

Reference Type RESULT
PMID: 23329469 (View on PubMed)

Coles LD, Patterson EE, Sheffield WD, Mavoori J, Higgins J, Michael B, Leyde K, Cloyd JC, Litt B, Vite C, Worrell GA. Feasibility study of a caregiver seizure alert system in canine epilepsy. Epilepsy Res. 2013 Oct;106(3):456-60. doi: 10.1016/j.eplepsyres.2013.06.007. Epub 2013 Aug 18.

Reference Type RESULT
PMID: 23962794 (View on PubMed)

Tzallas AT, Tsipouras MG, Rigas G, Tsalikakis DG, Karvounis EC, Chondrogiorgi M, Psomadellis F, Cancela J, Pastorino M, Waldmeyer MT, Konitsiotis S, Fotiadis DI. PERFORM: a system for monitoring, assessment and management of patients with Parkinson's disease. Sensors (Basel). 2014 Nov 11;14(11):21329-57. doi: 10.3390/s141121329.

Reference Type RESULT
PMID: 25393786 (View on PubMed)

Larner AJ. Teleneurology: an overview of current status. Pract Neurol. 2011 Oct;11(5):283-8. doi: 10.1136/practneurol-2011-000090.

Reference Type RESULT
PMID: 21921003 (View on PubMed)

Hani AJ, Mikati HM, Mikati MA. Genetics of pediatric epilepsy. Pediatr Clin North Am. 2015 Jun;62(3):703-22. doi: 10.1016/j.pcl.2015.03.013.

Reference Type RESULT
PMID: 26022171 (View on PubMed)

Bearden D, Strong A, Ehnot J, DiGiovine M, Dlugos D, Goldberg EM. Targeted treatment of migrating partial seizures of infancy with quinidine. Ann Neurol. 2014 Sep;76(3):457-61. doi: 10.1002/ana.24229. Epub 2014 Jul 26.

Reference Type RESULT
PMID: 25042079 (View on PubMed)

Wright S, Vincent A. Progress in autoimmune epileptic encephalitis. Curr Opin Neurol. 2016 Apr;29(2):151-7. doi: 10.1097/WCO.0000000000000304.

Reference Type RESULT
PMID: 26886357 (View on PubMed)

Patel J, Mercimek-Mahmutoglu S. Epileptic Encephalopathy in Childhood: A Stepwise Approach for Identification of Underlying Genetic Causes. Indian J Pediatr. 2016 Oct;83(10):1164-74. doi: 10.1007/s12098-015-1979-9. Epub 2016 Jan 29.

Reference Type RESULT
PMID: 26821542 (View on PubMed)

Kim EH, Ko TS. Cognitive impairment in childhood onset epilepsy: up-to-date information about its causes. Korean J Pediatr. 2016 Apr;59(4):155-64. doi: 10.3345/kjp.2016.59.4.155. Epub 2016 Apr 30.

Reference Type RESULT
PMID: 27186225 (View on PubMed)

Bonello M, Michael BD, Solomon T. Infective Causes of Epilepsy. Semin Neurol. 2015 Jun;35(3):235-44. doi: 10.1055/s-0035-1552619. Epub 2015 Jun 10.

Reference Type RESULT
PMID: 26060903 (View on PubMed)

Zhang Z, Wu J, Xu D, Zhao S, Lian D, Zhang D, Li L. Clinical characteristics and immunotherapy efficacy in autoimmune-associated benign epilepsy with centrotemporal spikes: A prospective cohort study. J Neuroimmunol. 2025 Jul 15;404:578603. doi: 10.1016/j.jneuroim.2025.578603. Epub 2025 Apr 4.

Reference Type DERIVED
PMID: 40209515 (View on PubMed)

Yin Y, Wu J, Wu S, Chen S, Cheng W, Li L, Wang H. Usefulness of brain FDG PET/CT imaging in pediatric patients with suspected autoimmune encephalitis from a prospective study. Eur J Nucl Med Mol Imaging. 2022 May;49(6):1918-1929. doi: 10.1007/s00259-021-05649-w. Epub 2021 Dec 23.

Reference Type DERIVED
PMID: 34939173 (View on PubMed)

Other Identifiers

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XH-16-029

Identifier Type: -

Identifier Source: org_study_id