Oxytocin Effects on Self and Other Processing

NCT ID: NCT02963194

Last Updated: 2016-11-15

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

44 participants

Study Classification

INTERVENTIONAL

Study Start Date

2015-11-30

Study Completion Date

2016-06-30

Brief Summary

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To determine whether the neuropeptide oxytocin (OXT) influences self-processing by investigating whether it increases the endowment effect in relation to both self and others.

Detailed Description

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In a double-blind, between- subject placebo (PLC) controlled design, investigator aimed to measure the effect of intranasal OXT on the endowment effect. All subjects completed a range of questionnaires measuring personality and affective traits and levels of anxiety before self-administration: Positive and Negative Affect Schedule (PANAS) , State-Trait Anxiety Inventory (STAI) , Beck Depression Inventory (BDI), self-esteem scale (SES). Subjects were asked to decide whether to buy or sell their own or others' (their mothers'/ fathers'/ classmate'/ strangers') possessions at various prices. Indifference point and brain activation were inluded into analysis as dependent variables.

Conditions

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Social Behavior

Keywords

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self-processing endowment effect neuroimage

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

BASIC_SCIENCE

Blinding Strategy

DOUBLE

Participants Investigators

Study Groups

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Oxytocin

Oxytoxin nasal spray

Group Type EXPERIMENTAL

Oxytocin

Intervention Type DRUG

Placebo

Placebo nasal spray

Group Type PLACEBO_COMPARATOR

Placebo

Intervention Type DRUG

Interventions

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Oxytocin

Intervention Type DRUG

Placebo

Intervention Type DRUG

Eligibility Criteria

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Inclusion Criteria

* healthy subjects without past or current psychiatric or neurological disorders

Exclusion Criteria

* history of head injury;
* claustrophobia;
* medical or psychiatric illness.
Minimum Eligible Age

18 Years

Maximum Eligible Age

27 Years

Eligible Sex

MALE

Accepts Healthy Volunteers

Yes

Sponsors

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University of Electronic Science and Technology of China

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Keith Kendrick, Dr.

Role: PRINCIPAL_INVESTIGATOR

University of Electronic Science and Technology of China

Locations

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School of Life Science and Technology, University of Electronic Science and Technology

Chengdu, Sichuan, China

Site Status

Countries

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China

Other Identifiers

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UESTC-neuSCAN-05

Identifier Type: -

Identifier Source: org_study_id