Platysma Trial - Platysma Suturing Versus no Sutures for Wound Closure After Primary Thyroid Surgery

NCT ID: NCT02951000

Last Updated: 2017-10-06

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

80 participants

Study Classification

INTERVENTIONAL

Study Start Date

2016-02-29

Study Completion Date

2017-06-30

Brief Summary

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Influence of the platysma suture on postoperative pain and wound healing.

Detailed Description

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Does a running platysma suture after primary thyroid resection alter direct postoperative pain, wound healing and long term cosmetic results.

Primary outcome measure is if the lack of a platysma-Suture decreases the postoperative pain (detected by the visual pain score 0-10) and reduces the pain medication (detected by the cumulative NSAID and opioid treatment per patient). The second Question to be answered is if the cosmetic scar result (detected by the Patient and Observer Scar Assessment Score) 6 month after thyroidectomy is better in the intervention group (no Platysma-Suture) or not.

Conditions

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Thyroid Disease

Keywords

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thyroidectomy postoperative pain wound healing

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

DOUBLE

Participants Outcome Assessors

Study Groups

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platysma suture

running suture of the platysma with 3/0 polyglactin

Group Type ACTIVE_COMPARATOR

platysma suture

Intervention Type PROCEDURE

no platysma suture

no platysma suture

Group Type ACTIVE_COMPARATOR

no platysma suture

Intervention Type PROCEDURE

Interventions

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platysma suture

Intervention Type PROCEDURE

no platysma suture

Intervention Type PROCEDURE

Eligibility Criteria

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Inclusion Criteria

* primary thyroid surgery

Exclusion Criteria

* previous neck surgery
* application of wound drainages
* preoperative diagnosed malignancy
* surgical extension beyond thyroid resection (e.g. lymphadenectomy)
* preexisting coagulopathy
* preexisting chronic pain syndromes
* preexisting dependency on pain reliefs
* preexisting disorders in wound healing (e.g. diabetes mellitus)
* intolerance to any study medication
Minimum Eligible Age

18 Years

Maximum Eligible Age

99 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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University Hospital Tuebingen

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Sven Müller, MD

Role: PRINCIPAL_INVESTIGATOR

University Tuebigen

Locations

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University Hospital Tuebingen

Tübingen, , Germany

Site Status

Countries

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Germany

References

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Senne M, Zein R, Falch C, Kirschniak A, Koenigsrainer A, Muller S. Randomized clinical trial of platysma muscle suture versus no suture for wound closure after thyroid surgery. Br J Surg. 2018 May;105(6):645-649. doi: 10.1002/bjs.10829. Epub 2018 Mar 26.

Reference Type DERIVED
PMID: 29579320 (View on PubMed)

Other Identifiers

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PLA1

Identifier Type: -

Identifier Source: org_study_id