Etiological Diagnosis of Urinary Stone in Chinese Children

NCT ID: NCT02949323

Last Updated: 2016-10-31

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Total Enrollment

200 participants

Study Classification

OBSERVATIONAL

Study Start Date

2016-11-30

Study Completion Date

2019-12-31

Brief Summary

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The incidence of nephrolithiasis in children has been reported to increase by approximately 6-10% annually, and the incidence is currently 50 per 100,000 children with high recurrent rate. Investigators aimed to determine the metabolic risk factors in Chinese children through metabolic evaluation.

In order to identify diagnostic criteria of hypocitraturia and hyperoxaluria in western country wether adapt to Chinese children, investigators aim to determine normal urine levels of oxalate and citrate in children without kidney stone.

Detailed Description

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Investigators aimed to determine the metabolic risk factors in 200 Chinese children with urinary stones through metabolic evaluation.

In order to identify diagnostic criteria of hypocitraturia and hyperoxaluria in western country wether adapt to Chinese children, investigators aim to determine normal urine levels of oxalate and citrate in children without kidney stone.

Conditions

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Urinary Stone

Keywords

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children renal stone metabolic evaluation Mutational analysis

Study Design

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Observational Model Type

CASE_CONTROL

Study Time Perspective

PROSPECTIVE

Study Groups

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children with urinary stones

children with urinary stones

urinary stone

Intervention Type OTHER

patients of group one have urinary stones

children without urinary stones

children without urinary stones

No interventions assigned to this group

Interventions

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urinary stone

patients of group one have urinary stones

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Children with urinary stones

Exclusion Criteria

* Anatomic urinary system abnormality, vesicoureteral reflux, urinary tract infection (temperature \>38°C and/or positive urine culture), solitary kidney, and renal insufficiency
Minimum Eligible Age

1 Year

Maximum Eligible Age

16 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Xinhua Hospital, Shanghai Jiao Tong University School of Medicine

OTHER

Sponsor Role lead

Responsible Party

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Hongquan Geng

Director, Department of Pediatric Urology

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Hongquan Geng, M.D

Role: STUDY_CHAIR

Department of Pediatric urology,Xin Hua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine

Lei He, M.D

Role: PRINCIPAL_INVESTIGATOR

Department of Pediatric urology,Xin Hua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine

Locations

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Department of Pediatric urology,Xin Hua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine

Shanghai, , China

Site Status

Countries

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China

Central Contacts

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Hongquan Geng, M.D

Role: CONTACT

Phone: +86-13801973493

Email: [email protected]

Lei He, M.D

Role: CONTACT

Phone: +86-13918845298

Email: [email protected]

Facility Contacts

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Hongquan geng, M.D

Role: primary

Lei He, M.D

Role: backup

Other Identifiers

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XH-16-026

Identifier Type: -

Identifier Source: org_study_id