Communication in Adolescents With ADHD

NCT ID: NCT02948270

Last Updated: 2016-10-28

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

COMPLETED

Total Enrollment

9 participants

Study Classification

OBSERVATIONAL

Study Start Date

2012-09-30

Study Completion Date

2013-06-30

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

The interpersonal problems of adolescents with ADHD may be the most debilitating aspect of their psychopathologic behaviour. This being said, the investigators still do not have a clear understanding of why it is the case that individuals with ADHD have such impaired social and communicative competence. In particular, research has not identified whether the communicative difficulties stems from deficits in taking the perspective of a communicative partner, or in being able to make use of this information in a systematic way. This study will compare adolescents with ADHD to adolescents not diagnosed with ADHD and their performance on a number of social inference and communication tests. This study hypothesizes that persons with ADHD will not perform as effectively as control participants on the social inference and communication tests, and will evidence lower WM score. As well, this study hypothesizes that a working memory/cognitive load task will impede performance on certain social inference and communication tests to a greater extent in the ADHD population than in the control group.

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

The first objective of this project is to examine whether individuals with ADHD symptoms are less able than their non-ADHD counterparts to use the perspective of their conversational partner, a deficiency which in turn contributes to increased difficulty in more complex communicative contexts.

The second objective is to assess the degree to which communicative difficulties stem from the core cognitive deficits faced by individuals with ADHD. Only recently has the developmental literature uncovered the relationship between cognitive skills and communicative perspective-taking. That is, children who have more proficient inhibition are better able to suppress their own perspective in order to take into account the perspective of a conversational partner (Nilsen \& Graham, 2009). Furthermore, working memory skills have been found to relate to children's ability to understand the intentions of speakers who use figurative language (e.g., Filippova \& Astington, 2008).Thus, it may be that a weakness in inhibition and working memory (over and above possible weakness in their mentalizing skills) prevents children with ADHD from using the perspective of their conversational partner during communicative interactions.

General research questions: Are adolescents with ADHD less able to appreciate the perspective of conversational partners? Does this relate to their core executive deficits?

Specific Research Questions Summary:

1. Do adolescents with ADHD show less social inference ability? Is this ability exacerbated by increased cognitive demands (e.g., working memory)?
2. Do adolescents with ADHD show less communicative perspective-taking? Is this related to their inhibitory control skills?
3. Do adolescents with ADHD overestimate the clarity of their intended messages in texts? Is this 'overestimation' more closely related to difficulties with appreciating 'common ground' when constructing text messages?
4. Do adolescents with ADHD conflate their own knowledge with that of a listener in third-person perspective tasks? Is this related to IC / WM?

Other questions that can be examined in the proposed study, but not outlined specifically here:
5. Do adolescents that show difficulty on the communicative perspective-taking tasks show worse overall social competence? (self/parent report)
6. Is the social outcome worse for girls than boys, due to the more intimate social milieu of girls compared to relatively loose social networks of adolescent boys? (e.g., Ohan \& Honston, 2007).
7. Do self-reported EF difficulties relate to actual EF performance? Do self-reported EF difficulties relate to performance on the perspective-taking tasks?

Proposed procedure:

* Adolescents who met diagnostic criteria in previous clinical/research assessment are invited to come back to SickKids to participate in research study (ages 13-17)
* Adolescent controls are tested through local high schools

Task summary:

Social / communicative perspective-taking tasks:

* The Awareness of Social Inference Test (TASIT, McDonald et al., 2002)
* Without working memory load (10 min)
* With working memory load (10 min)
* Computerized Perspective-taking (Apperly) (10-15 min)
* Texting task (similar to Kruger et al., ) (15 min)
* Story Vignette task (15 min)

Executive function tasks:

Inhibitory Control measures:

* Stroop (5 min)
* Stop Signal (15 min)

Working Memory measures:

* Sentence span (10 min)
* WRAML finger windows (10 min)

Report measures:

* The SNAP-IV Teacher and Parent Rating Scale
* Social Skills Improvement System (SSIS, Gresham \& Elliot, 2007) parent report 3-18
* Strengths and Difficulties Questionnaire (SDQ) Adolescent:
* Behavior Rating Inventory of Executive Functioning (BRIEF) SR 11-18 years
* Social Skills Improvement System (SSIS, Gresham \& Elliot, 2007) student report 13-18
* Strengths and Difficulties Questionnaire (SDQ) Parent

Information required from past adolescents' past participation:

* ADHD diagnostic status
* Any other diagnoses (e.g., LD / ODD)
* Cognitive level (FSIQ, VCI, PRI)

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Attention Deficit Hyperactivity Disorder

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Observational Model Type

CASE_CONTROL

Study Time Perspective

PROSPECTIVE

Study Groups

Review each arm or cohort in the study, along with the interventions and objectives associated with them.

Adolescents with ADHD

Adolescents who met diagnostic criteria in previous clinical/research assessment are invited to come back to SickKids to participate (ages 13-17)

No interventions assigned to this group

Adolescents without ADHD

Adolescent controls (ages 13-17) are tested through local high schools

No interventions assigned to this group

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

* ADHD

Exclusion Criteria

* Other mental health diagnoses, such as ASD.
Minimum Eligible Age

14 Years

Maximum Eligible Age

17 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

Meet the organizations funding or collaborating on the study and learn about their roles.

The Hospital for Sick Children

OTHER

Sponsor Role lead

Responsible Party

Identify the individual or organization who holds primary responsibility for the study information submitted to regulators.

Rosemary Tannock

Senior Scientist

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

Learn about the lead researchers overseeing the trial and their institutional affiliations.

Bruce Ferguson, MD

Role: PRINCIPAL_INVESTIGATOR

The Hospital for Sick Children

Rosemary Tannock, MD

Role: PRINCIPAL_INVESTIGATOR

The Hospital for Sick Children

Locations

Explore where the study is taking place and check the recruitment status at each participating site.

The Hospital for Sick Children

Toronto, Ontario, Canada

Site Status

Countries

Review the countries where the study has at least one active or historical site.

Canada

Other Identifiers

Review additional registry numbers or institutional identifiers associated with this trial.

1000026311

Identifier Type: -

Identifier Source: org_study_id