Whole Body PET-MRI in Paediatric and Adolescent Lymphoma

NCT ID: NCT02935348

Last Updated: 2016-10-17

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Total Enrollment

25 participants

Study Classification

OBSERVATIONAL

Study Start Date

2014-02-28

Study Completion Date

2017-05-31

Brief Summary

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Children and adolescents with Hodgkin lymphoma currently undergo multiple investigations including a separate PET and MRI scans during their treatment.

Investigators want to investigate if a combined PET-MRI scan could give the same information.

Children who join our study will have an extra scan twice during their treatment

Detailed Description

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Children and adolescents with Hodgkin lymphoma currently undergo multiple investigations including a separate PET and MRI scans during their treatment.

Investigators want to investigate if a combined PET-MRI scan could give the same information.

Children who join our study will have an extra scan twice during their treatment

Routine whole body clinical MRI will be performed according to current clinical standard of care. Axial and coronal imaging from the maxilla to proximal femurs will be performed using a combination of T1 and T2 weighted sequences, with and without gadolinium administration.

Conditions

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Lymphoma

Study Design

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Observational Model Type

CASE_ONLY

Study Time Perspective

PROSPECTIVE

Interventions

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Whole Body MRI

Routine whole body clinical MRI will be performed according to current clinical standard of care. Axial and coronal imaging from the maxilla to proximal femurs will be performed using a combination of T1 and T2 weighted sequences, with and without gadolinium administration.

Intervention Type RADIATION

Eligibility Criteria

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Inclusion Criteria

1. Suspected or histologically confirmed Hodgkin lymphoma
2. Male or female participants
3. Age 0-20 years inclusive
4. Entered into the EuroNet PHL-C1 trial, LP1 trial or successor Euronet trials, including Euronet PHL C2 due to open from 2013 onwards or planned to receive chemotherapy regimens of said trials without being formally entered into the trial.
5. Participant/Guardian/Parental written informed consent

Exclusion Criteria

1. Participants with contraindications to MRI (including cardiac pacemakers or non-MRI compatible intracranial vascular clips)
2. Participants who are pregnant or nursing
Maximum Eligible Age

20 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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University College, London

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Paul Humphries

Role: PRINCIPAL_INVESTIGATOR

UCL

Locations

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Centre for Medical Imaging

London, London, United Kingdom

Site Status RECRUITING

Countries

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United Kingdom

Central Contacts

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Joey J Clemente

Role: CONTACT

02034479094 ext. 79094

Facility Contacts

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Joey J Clemente

Role: primary

02034479194 ext. 79094

Other Identifiers

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13/0268

Identifier Type: -

Identifier Source: org_study_id

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