Evaluation of Post Operative Pain Following Indirect Pulp Capping Using Antibacterial Bonding System

NCT ID: NCT02930135

Last Updated: 2017-11-20

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

36 participants

Study Classification

INTERVENTIONAL

Study Start Date

2015-08-31

Study Completion Date

2017-03-31

Brief Summary

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The aim of this study is to compare the clinical and radiographic success of indirect pulp capping of vital young permanent teeth with deep caries using two-step antibacterial bonding system versus conventional one.

Detailed Description

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The study was carried out on patients attending outpatient clinic in Pediatric and Dental Public Health department- Faculty of Oral and Dental Medicine Cairo University- Egypt.

\*\*Sample size: On searching, no previous studies were conducted using neither conventional bonding nor antibacterial bonding in indirect pulp treatment in young permanent teeth, so sample size will be measured by estimation rather than calculation.

So, all patients attended outpatient clinic in Pediatric and Dental Public Health department- Faculty of Oral and Dental Medicine Cairo University- Egypt, In the period from 1/8/2015 - 31/10/2015 were enrolled for this study if they compatible with eligibility criteria.

\*\*Clinical Procedures:

I. Diagnosis:

Full personal, medical and dental history,clinical and radiographic examination.

II. Allocation concealment:

Selected envelopes will be opened in the first visit to allocate the patients to their treatment groups .

III.Intervention:

A- Experimental Group: Indirect pulp capping with Antibacterial Two-Step Bonding System:

1. Local anesthesia.
2. Isolation of tooth with rubber dam.
3. Opening of the cavity and the removal of undermined enamel using high speed hand-piece with copious air/water spray and round burs.
4. Caries at the lateral walls of the cavity and at the dentin-enamel junction is completely removed with excavators or low speed round burs.
5. Partial removal of carious dentin (only soft disorganized dentin is removed) on the pulp wall.
6. Washing the cavity with distilled water and dryness with triple airway syringe and sterile cotton.
7. Apply antibacterial light-cure, self-etching bonding agent (Clearfil SE Protect, Kuraray America, Inc.)
8. Light-cured bulk fill composite (x-tra fil, VOCO) will be used as final tooth restoration.
9. Postoperative digital radiograph will be taken as a base line.

B- Comparative Group: Indirect pulp capping with Conventional Two-Step Bonding System Same as that of the experimental group EXCEPT steps number 5 as conventional light-cure, self-etching bonding agent (Clearfil SE Bond, Kuraray America, Inc.) will be applied into cavity according to manufacturer's instruction.

IV. Follow up and postoperative instructions:

\- Patients will be recalled 48 hours after the treatment then at 2, 9 months

Conditions

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Deep Caries

Keywords

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Indirect Pulp Capping, Young Permanent Molars

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

TRIPLE

Participants Investigators Outcome Assessors

Study Groups

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Antibacterial Bond

Indirect pulp capping using antibacterial bond and x-tra fil composite

1. Local anesthesia administration
2. Isolation of tooth with rubber dam
3. Opening of the cavity and the removal of undermined enamel
4. Caries at the lateral walls of the cavity and at the dentin-enamel junction is completely removed
5. Partial removal of carious dentin on the pulp wall.
6. Washing the cavity and dryness
7. Apply antibacterial light-cure, self-etching bonding agent (Clearfil SE Protect, Kuraray America, Inc.)
8. Light-cured bulk fill composite (x-tra fil, VOCO) used as final tooth restoration.

Group Type EXPERIMENTAL

Indirect pulp capping

Intervention Type PROCEDURE

Removal of superficial caries in young permanent molars that my expose tooth pulp if totally removed leaving deep carious layers to be sealed inside with two step bonding system and bulk fill composite as a final restoration

Conventional Bond

Indirect pulp capping using conventional bond and x-tra fil composite

1. Local anesthesia administration
2. Isolation of tooth with rubber dam
3. Opening of the cavity and the removal of undermined enamel
4. Caries at the lateral walls of the cavity and at the dentin-enamel junction is completely removed
5. Partial removal of carious dentin on the pulp wall.
6. Washing the cavity and dryness
7. Apply conventional light-cure, self-etching bonding agent (Clearfil SE Bond, Kuraray America, Inc.)
8. Light-cured bulk fill composite (x-tra fil, VOCO) used as final tooth restoration.

Group Type ACTIVE_COMPARATOR

Indirect pulp capping

Intervention Type PROCEDURE

Removal of superficial caries in young permanent molars that my expose tooth pulp if totally removed leaving deep carious layers to be sealed inside with two step bonding system and bulk fill composite as a final restoration

Interventions

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Indirect pulp capping

Removal of superficial caries in young permanent molars that my expose tooth pulp if totally removed leaving deep carious layers to be sealed inside with two step bonding system and bulk fill composite as a final restoration

Intervention Type PROCEDURE

Other Intervention Names

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Partial caries removal

Eligibility Criteria

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Inclusion Criteria

1. Patients free from any systemic diseases.
2. Young permanent molars with deep carious lesions according to clinical and radiographic examination and at risk of pulp exposure if complete caries is removed.
3. Absence of clinical pathologic signs (fistula, swelling and abnormal tooth mobility)
4. The absence of clinical symptoms of irreversible pulpitis such as spontaneous pain or pain persisting after the disappearance of the existing stimulus or sensitivity to pressure.
5. Absence of adverse radiographic findings (interradicular or periapical radiolucencies, thickening of the periodontal membrane space, internal and external root resorption).
6. Compliant patient/parent.

Exclusion Criteria

1. Teeth with previous restorative treatment.
2. Unrestorable teeth.
3. Uncooperative patients.
Minimum Eligible Age

6 Years

Maximum Eligible Age

14 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Cairo University

OTHER

Sponsor Role lead

Responsible Party

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Shaimaa Mohamed Sabry Mostafa El Hanafy

Assistant Lecturer in Pediatric Dentistry and Dental Public Health Department

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Dalia M Moheb, PhD

Role: STUDY_DIRECTOR

Cairo University

References

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Miyashita H, Worthington HV, Qualtrough A, Plasschaert A. Pulp management for caries in adults: maintaining pulp vitality. Cochrane Database Syst Rev. 2007 Apr 18;(2):CD004484. doi: 10.1002/14651858.CD004484.pub2.

Reference Type BACKGROUND
PMID: 17443547 (View on PubMed)

Orhan AI, Oz FT, Ozcelik B, Orhan K. A clinical and microbiological comparative study of deep carious lesion treatment in deciduous and young permanent molars. Clin Oral Investig. 2008 Dec;12(4):369-78. doi: 10.1007/s00784-008-0208-6. Epub 2008 Jun 12.

Reference Type BACKGROUND
PMID: 18548292 (View on PubMed)

Maltz M, Garcia R, Jardim JJ, de Paula LM, Yamaguti PM, Moura MS, Garcia F, Nascimento C, Oliveira A, Mestrinho HD. Randomized trial of partial vs. stepwise caries removal: 3-year follow-up. J Dent Res. 2012 Nov;91(11):1026-31. doi: 10.1177/0022034512460403. Epub 2012 Sep 14.

Reference Type BACKGROUND
PMID: 22983407 (View on PubMed)

Reichert C. Randomized trial of partial vs. stepwise caries removal: 3-year follow-up. J Orofac Orthop. 2013 May 8. doi: 10.1007/s00056-013-0147-y. Online ahead of print. No abstract available.

Reference Type BACKGROUND
PMID: 23649283 (View on PubMed)

Bergenholtz G, Axelsson S, Davidson T, Frisk F, Hakeberg M, Kvist T, Norlund A, Petersson A, Portenier I, Sandberg H, Tranaeus S, Mejare I. Treatment of pulps in teeth affected by deep caries - A systematic review of the literature. Singapore Dent J. 2013 Dec;34(1):1-12. doi: 10.1016/j.sdj.2013.11.001.

Reference Type BACKGROUND
PMID: 24360260 (View on PubMed)

Other Identifiers

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1-10-2014

Identifier Type: -

Identifier Source: org_study_id