Trial Outcomes & Findings for Atropine in Catecholaminergic Polymorphic Ventricular Tachycardia (CPVT) (NCT NCT02927223)
NCT ID: NCT02927223
Last Updated: 2020-01-28
Results Overview
Recruitment status
COMPLETED
Study phase
NA
Target enrollment
6 participants
Primary outcome timeframe
20 minutes during exercise
Results posted on
2020-01-28
Participant Flow
Participant milestones
| Measure |
Treadmill Then Treadmill With Atropine
Patients will undergo treadmill exercise at baseline, then Patients will undergo treadmill exercise after IV atropine
Atropine
Exercise treadmill test
|
|---|---|
|
Overall Study
STARTED
|
6
|
|
Overall Study
COMPLETED
|
6
|
|
Overall Study
NOT COMPLETED
|
0
|
Reasons for withdrawal
Withdrawal data not reported
Baseline Characteristics
Atropine in Catecholaminergic Polymorphic Ventricular Tachycardia (CPVT)
Baseline characteristics by cohort
| Measure |
Treadmill Then Treadmill With Atropine
n=6 Participants
Patients will undergo treadmill exercise at baseline, then Patients will undergo treadmill exercise after IV atropine
Atropine
Exercise treadmill test
|
|---|---|
|
Age, Continuous
|
38 years
n=93 Participants
|
|
Sex: Female, Male
Female
|
1 Participants
n=93 Participants
|
|
Sex: Female, Male
Male
|
5 Participants
n=93 Participants
|
|
Ethnicity (NIH/OMB)
Hispanic or Latino
|
0 Participants
n=93 Participants
|
|
Ethnicity (NIH/OMB)
Not Hispanic or Latino
|
6 Participants
n=93 Participants
|
|
Ethnicity (NIH/OMB)
Unknown or Not Reported
|
0 Participants
n=93 Participants
|
|
Race (NIH/OMB)
American Indian or Alaska Native
|
0 Participants
n=93 Participants
|
|
Race (NIH/OMB)
Asian
|
0 Participants
n=93 Participants
|
|
Race (NIH/OMB)
Native Hawaiian or Other Pacific Islander
|
0 Participants
n=93 Participants
|
|
Race (NIH/OMB)
Black or African American
|
0 Participants
n=93 Participants
|
|
Race (NIH/OMB)
White
|
6 Participants
n=93 Participants
|
|
Race (NIH/OMB)
More than one race
|
0 Participants
n=93 Participants
|
|
Race (NIH/OMB)
Unknown or Not Reported
|
0 Participants
n=93 Participants
|
|
Region of Enrollment
United States
|
6 participants
n=93 Participants
|
PRIMARY outcome
Timeframe: 20 minutes during exerciseOutcome measures
| Measure |
Treadmill
n=6 Participants
Patients will undergo treadmill exercise at baseline,
Exercise treadmill test
|
Treadmill With Atropine
n=6 Participants
Patients will undergo treadmill exercise after IV atropine
Atropine
Exercise treadmill test
|
|---|---|---|
|
Number of Ventricular Ectopic Beats Recorded During Exercise (and Recovery)
|
46 number of ventricular beats
Interval 6.0 to 192.0
|
0 number of ventricular beats
Interval 0.0 to 29.0
|
Adverse Events
Treadmill
Serious events: 0 serious events
Other events: 0 other events
Deaths: 0 deaths
Treadmill With Atropine
Serious events: 0 serious events
Other events: 0 other events
Deaths: 0 deaths
Serious adverse events
Adverse event data not reported
Other adverse events
Adverse event data not reported
Additional Information
Dr. Prince Kannankeril
Vanderbilt University Medical Center
Phone: 615-322-7447
Email: [email protected]
Results disclosure agreements
- Principal investigator is a sponsor employee
- Publication restrictions are in place