Effects of Herbal Products on Reduction of Radiation-induced Dermatitis in Breast Cancer Patients
NCT ID: NCT02922244
Last Updated: 2018-06-25
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
NA
150 participants
INTERVENTIONAL
2016-05-31
2018-06-30
Brief Summary
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Detailed Description
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Conditions
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Study Design
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RANDOMIZED
PARALLEL
PREVENTION
TRIPLE
Study Groups
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Standard skin care
standard skin care
No interventions assigned to this group
Control
Moisture Cream
Control
Apply moisture cream to the treatment skin everyday after radiation therapy
Cucumber cream
Apply Cucumber cream everyday after radiation therapy on the treatment aria skin.
Cucumber cream
Apply cucumber cream to the treatment skin everyday after radiation therapy
Centella cream
Apply Centella asiatica cream everyday after radiation therapy on the treatment aria skin.
Centella cream
Apply centella cream to the treatment skin everyday after radiation therapy
Thunbergia cream
Apply Thunbergia cream everyday after radiation therapy on the treatment aria skin.
Thunbergia cream
Apply thunbergia cream to the treatment skin everyday after radiation therapy
Interventions
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Control
Apply moisture cream to the treatment skin everyday after radiation therapy
Cucumber cream
Apply cucumber cream to the treatment skin everyday after radiation therapy
Centella cream
Apply centella cream to the treatment skin everyday after radiation therapy
Thunbergia cream
Apply thunbergia cream to the treatment skin everyday after radiation therapy
Other Intervention Names
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Eligibility Criteria
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Inclusion Criteria
* Diagnosed with Breast cancer
* On course of external Radiation therapy
Exclusion Criteria
* Previously underwent external Radiation therapy
* Illiterate
20 Years
80 Years
ALL
No
Sponsors
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Chulabhorn Cancer Center
OTHER
Responsible Party
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Saengrawee Thanthong
Principal Investigator
Principal Investigators
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Saengrawee Thanthong, M.N.S.
Role: PRINCIPAL_INVESTIGATOR
54 moo 4 Kampangpet 6 Taladbangken Laksi Bangkok, THAILAND 10210
Locations
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ChulaBhorn Hospital
Bangkok, , Thailand
Countries
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References
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Chen YJ, Dai YS, Chen BF, Chang A, Chen HC, Lin YC, Chang KH, Lai YL, Chung CH, Lai YJ. The effect of tetrandrine and extracts of Centella asiatica on acute radiation dermatitis in rats. Biol Pharm Bull. 1999 Jul;22(7):703-6. doi: 10.1248/bpb.22.703.
Gohil KJ, Patel JA, Gajjar AK. Pharmacological Review on Centella asiatica: A Potential Herbal Cure-all. Indian J Pharm Sci. 2010 Sep;72(5):546-56. doi: 10.4103/0250-474X.78519.
Haleagrahara N, Ponnusamy K. Neuroprotective effect of Centella asiatica extract (CAE) on experimentally induced parkinsonism in aged Sprague-Dawley rats. J Toxicol Sci. 2010 Feb;35(1):41-7. doi: 10.2131/jts.35.41.
Johnke RM, Sattler JA, Allison RR. Radioprotective agents for radiation therapy: future trends. Future Oncol. 2014 Dec;10(15):2345-57. doi: 10.2217/fon.14.175.
McQuestion M. Evidence-based skin care management in radiation therapy. Semin Oncol Nurs. 2006 Aug;22(3):163-73. doi: 10.1016/j.soncn.2006.04.004.
Momm F, Weissenberger C, Bartelt S, Henke M. Moist skin care can diminish acute radiation-induced skin toxicity. Strahlenther Onkol. 2003 Oct;179(10):708-12. doi: 10.1007/s00066-003-1142-9.
Nema NK, Maity N, Sarkar B, Mukherjee PK. Cucumis sativus fruit-potential antioxidant, anti-hyaluronidase, and anti-elastase agent. Arch Dermatol Res. 2011 May;303(4):247-52. doi: 10.1007/s00403-010-1103-y. Epub 2010 Dec 14.
Wei LS, Wee W. Chemical composition and antimicrobial activity of Cymbopogon nardus citronella essential oil against systemic bacteria of aquatic animals. Iran J Microbiol. 2013 Jun;5(2):147-52.
Other Identifiers
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005/2559
Identifier Type: -
Identifier Source: org_study_id
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