Evaluation of Changes in Prescribing Behavior of ER/LA Opioid Prescribers

NCT ID: NCT02920762

Last Updated: 2016-09-30

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Total Enrollment

5575834 participants

Study Classification

OBSERVATIONAL

Brief Summary

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A study will be performed to evaluate changes in prescribing behavior of prescribers of ER/LA opioids

Detailed Description

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A study will be performed to evaluate changes in prescribing behavior of prescribers.

1. For products that are indicated for use in opioid-tolerant patients only (i.e., fentanyl transdermal patches, extended-release hydromorphone pills and extended-release morphine pills \>90mg), describe trends in the proportion of prescriptions for these products to opioid-non-tolerant patients in the year preceding the availability of REMS-compliant CE courses and compare the proportion of prescriptions to opioid non-tolerant patients pre- versus post-REMS CE course availability
2. For products whose labels indicate that higher dosage strengths should only be used in opioid-tolerant patients, describe trends in the proportion of prescriptions prescribed to opioid non-tolerant patients with a high starting dosage strength; compare the proportion of prescriptions for such products that are prescribed to opioid non-tolerant patients with a high starting dosage strength pre- versus post-REMS CE course availability
3. Describe trends in the proportion of prescriptions for ER/LA opioids prescribed to patients that have early refills of prescriptions and compare this proportion pre- versus post-REMS CE course availability.
4. Compare the concomitant use of benzodiazepines with ER/LA opioids before and after REMS implementation.

Conditions

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Opioid Related Disorders Opiate Addiction Narcotic Abuse Drug Abuse

Study Design

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Observational Model Type

COHORT

Study Time Perspective

RETROSPECTIVE

Study Groups

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Buprenorphine

on-interventional study - retrospective database review

Intervention Type OTHER

Fentanyl

on-interventional study - retrospective database review

Intervention Type OTHER

Hydromorphone HCl

on-interventional study - retrospective database review

Intervention Type OTHER

Morphine Sulfate

on-interventional study - retrospective database review

Intervention Type OTHER

Morphine Sulfate Beads

on-interventional study - retrospective database review

Intervention Type OTHER

Oxycodone HCl

on-interventional study - retrospective database review

Intervention Type OTHER

Oxymorphone HCl

on-interventional study - retrospective database review

Intervention Type OTHER

Tapentadol

on-interventional study - retrospective database review

Intervention Type OTHER

Interventions

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on-interventional study - retrospective database review

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Subjects filling a prescription for a product of interest during the specified time period will be included.

Exclusion Criteria

* None
Maximum Eligible Age

100 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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ER/LA Opioid REMS Program Companies (RPC)

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Other Identifiers

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Assessment 7

Identifier Type: -

Identifier Source: org_study_id