Trial Outcomes & Findings for Movement Pattern Training in People With Intra-articular, Prearthritic Hip Disorders (NCT NCT02913222)

NCT ID: NCT02913222

Last Updated: 2023-03-27

Results Overview

Percentage of study participants who attend 90% (9/10) of the supervised treatment sessions.

• Recruitment status: COMPLETED
• Study phase: NA
• Target enrollment: 46 participants
• Primary outcome timeframe: Immediately after treatment (13 weeks after baseline)
• Results posted on: 2023-03-27

Participant Flow

Participant milestones

Measure	Movement Pattern Training (MPT) Treatment: 10 sessions over 12 weeks and a home program provided by a physical therapist. Treatment includes assessment of patient goals and patient education. Movement Pattern Training (MPT) will focus on task-specific training to improve lower extremity movement patterns during basic tasks, such as sit to stand and stairs, and reported patient-specific tasks. Patient education will include instruction in abnormal movement patterns and methods to optimize movement patterns during each task. Exercises will include repeated practice of tasks using optimized movement patterns. Verbal cues and visual aids will be used to assist the participant. Difficulty of the task-specific activities will be progressed by varying repetitions performed, increasing load or changing the support surface. Rehabilitation: Comparison of two rehabilitation approaches	Standard Rehabilitation Treatment: 10 sessions over 12 weeks and a home program provided by a physical therapist. Treatment includes assessment of patient goals and patient education. For the Standard Rehabilitation, focus will be on progressive lower extremity and trunk strengthening and lower extremity flexibility. Patient education will include instruction to modify intensity, frequency or duration of patient-specific tasks. Using current clinical practice guidelines and previous reports, strengthening and flexibility exercises will be prescribed and progressed by varying the repetitions performed or increasing the load. Rehabilitation: Comparison of two rehabilitation approaches
Overall Study STARTED	23	23
Overall Study COMPLETED	22	21
Overall Study NOT COMPLETED	1	2

Reasons for withdrawal

Withdrawal data not reported

Baseline Characteristics

One participant in the Movement Pattern group withdrew due to time constraints. Three participants in the Standard group withdrew: 1 due to time constraints and 2 were unable to be located.

Baseline characteristics by cohort

Measure	Movement Pattern Training (MPT) n=23 Participants Treatment: 10 sessions over 12 weeks and a home program provided by a physical therapist. Treatment includes assessment of patient goals and patient education. Movement Pattern Training (MPT) will focus on task-specific training to improve lower extremity movement patterns during basic tasks, such as sit to stand and stairs, and reported patient-specific tasks. Patient education will include instruction in abnormal movement patterns and methods to optimize movement patterns during each task. Exercises will include repeated practice of tasks using optimized movement patterns. Verbal cues and visual aids will be used to assist the participant. Difficulty of the task-specific activities will be progressed by varying repetitions performed, increasing load or changing the support surface. Rehabilitation: Comparison of two rehabilitation approaches	Standard Rehabilitation n=23 Participants Treatment: 10 sessions over 12 weeks and a home program provided by a physical therapist. Treatment includes assessment of patient goals and patient education. For the Standard Rehabilitation, focus will be on progressive lower extremity and trunk strengthening and lower extremity flexibility. Patient education will include instruction to modify intensity, frequency or duration of patient-specific tasks. Using current clinical practice guidelines and previous reports, strengthening and flexibility exercises will be prescribed and progressed by varying the repetitions performed or increasing the load. Rehabilitation: Comparison of two rehabilitation approaches	Total n=46 Participants Total of all reporting groups
Age, Categorical <=18 years	1 Participants n=23 Participants	0 Participants n=23 Participants	1 Participants n=46 Participants
Age, Categorical Between 18 and 65 years	22 Participants n=23 Participants	23 Participants n=23 Participants	45 Participants n=46 Participants
Age, Categorical >=65 years	0 Participants n=23 Participants	0 Participants n=23 Participants	0 Participants n=46 Participants
Age, Continuous	27.6 years STANDARD_DEVIATION 5.0 • n=22 Participants • One participant in the Movement Pattern group withdrew due to time constraints. Three participants in the Standard group withdrew: 1 due to time constraints and 2 were unable to be located.	30.2 years STANDARD_DEVIATION 5.2 • n=20 Participants • One participant in the Movement Pattern group withdrew due to time constraints. Three participants in the Standard group withdrew: 1 due to time constraints and 2 were unable to be located.	28.9 years STANDARD_DEVIATION 5.2 • n=42 Participants • One participant in the Movement Pattern group withdrew due to time constraints. Three participants in the Standard group withdrew: 1 due to time constraints and 2 were unable to be located.
Sex: Female, Male Female	13 Participants n=22 Participants • One participant in the Movement Pattern group withdrew due to time constraints. Three participants in the Standard group withdrew: 1 due to time constraints and 2 were unable to be located.	12 Participants n=20 Participants • One participant in the Movement Pattern group withdrew due to time constraints. Three participants in the Standard group withdrew: 1 due to time constraints and 2 were unable to be located.	25 Participants n=42 Participants • One participant in the Movement Pattern group withdrew due to time constraints. Three participants in the Standard group withdrew: 1 due to time constraints and 2 were unable to be located.
Sex: Female, Male Male	9 Participants n=22 Participants • One participant in the Movement Pattern group withdrew due to time constraints. Three participants in the Standard group withdrew: 1 due to time constraints and 2 were unable to be located.	8 Participants n=20 Participants • One participant in the Movement Pattern group withdrew due to time constraints. Three participants in the Standard group withdrew: 1 due to time constraints and 2 were unable to be located.	17 Participants n=42 Participants • One participant in the Movement Pattern group withdrew due to time constraints. Three participants in the Standard group withdrew: 1 due to time constraints and 2 were unable to be located.
Race (NIH/OMB) American Indian or Alaska Native	1 Participants n=22 Participants • One participant in the Movement Pattern group withdrew due to time constraints. Three participants in the Standard group withdrew: 1 due to time constraints and 2 were unable to be located.	0 Participants n=20 Participants • One participant in the Movement Pattern group withdrew due to time constraints. Three participants in the Standard group withdrew: 1 due to time constraints and 2 were unable to be located.	1 Participants n=42 Participants • One participant in the Movement Pattern group withdrew due to time constraints. Three participants in the Standard group withdrew: 1 due to time constraints and 2 were unable to be located.
Race (NIH/OMB) Asian	1 Participants n=22 Participants • One participant in the Movement Pattern group withdrew due to time constraints. Three participants in the Standard group withdrew: 1 due to time constraints and 2 were unable to be located.	0 Participants n=20 Participants • One participant in the Movement Pattern group withdrew due to time constraints. Three participants in the Standard group withdrew: 1 due to time constraints and 2 were unable to be located.	1 Participants n=42 Participants • One participant in the Movement Pattern group withdrew due to time constraints. Three participants in the Standard group withdrew: 1 due to time constraints and 2 were unable to be located.
Race (NIH/OMB) Native Hawaiian or Other Pacific Islander	0 Participants n=22 Participants • One participant in the Movement Pattern group withdrew due to time constraints. Three participants in the Standard group withdrew: 1 due to time constraints and 2 were unable to be located.	0 Participants n=20 Participants • One participant in the Movement Pattern group withdrew due to time constraints. Three participants in the Standard group withdrew: 1 due to time constraints and 2 were unable to be located.	0 Participants n=42 Participants • One participant in the Movement Pattern group withdrew due to time constraints. Three participants in the Standard group withdrew: 1 due to time constraints and 2 were unable to be located.
Race (NIH/OMB) Black or African American	4 Participants n=22 Participants • One participant in the Movement Pattern group withdrew due to time constraints. Three participants in the Standard group withdrew: 1 due to time constraints and 2 were unable to be located.	0 Participants n=20 Participants • One participant in the Movement Pattern group withdrew due to time constraints. Three participants in the Standard group withdrew: 1 due to time constraints and 2 were unable to be located.	4 Participants n=42 Participants • One participant in the Movement Pattern group withdrew due to time constraints. Three participants in the Standard group withdrew: 1 due to time constraints and 2 were unable to be located.
Race (NIH/OMB) White	15 Participants n=22 Participants • One participant in the Movement Pattern group withdrew due to time constraints. Three participants in the Standard group withdrew: 1 due to time constraints and 2 were unable to be located.	20 Participants n=20 Participants • One participant in the Movement Pattern group withdrew due to time constraints. Three participants in the Standard group withdrew: 1 due to time constraints and 2 were unable to be located.	35 Participants n=42 Participants • One participant in the Movement Pattern group withdrew due to time constraints. Three participants in the Standard group withdrew: 1 due to time constraints and 2 were unable to be located.
Race (NIH/OMB) More than one race	1 Participants n=22 Participants • One participant in the Movement Pattern group withdrew due to time constraints. Three participants in the Standard group withdrew: 1 due to time constraints and 2 were unable to be located.	0 Participants n=20 Participants • One participant in the Movement Pattern group withdrew due to time constraints. Three participants in the Standard group withdrew: 1 due to time constraints and 2 were unable to be located.	1 Participants n=42 Participants • One participant in the Movement Pattern group withdrew due to time constraints. Three participants in the Standard group withdrew: 1 due to time constraints and 2 were unable to be located.
Race (NIH/OMB) Unknown or Not Reported	0 Participants n=22 Participants • One participant in the Movement Pattern group withdrew due to time constraints. Three participants in the Standard group withdrew: 1 due to time constraints and 2 were unable to be located.	0 Participants n=20 Participants • One participant in the Movement Pattern group withdrew due to time constraints. Three participants in the Standard group withdrew: 1 due to time constraints and 2 were unable to be located.	0 Participants n=42 Participants • One participant in the Movement Pattern group withdrew due to time constraints. Three participants in the Standard group withdrew: 1 due to time constraints and 2 were unable to be located.
Measured BMI	24.9 Kg/m^2 STANDARD_DEVIATION 6.1 • n=22 Participants • One participant in the Movement Pattern group withdrew due to time constraints. Three participants in the Standard group withdrew: 1 due to time constraints and 2 were unable to be located.	25.6 Kg/m^2 STANDARD_DEVIATION 6.1 • n=20 Participants • One participant in the Movement Pattern group withdrew due to time constraints. Three participants in the Standard group withdrew: 1 due to time constraints and 2 were unable to be located.	25.2 Kg/m^2 STANDARD_DEVIATION 6.0 • n=42 Participants • One participant in the Movement Pattern group withdrew due to time constraints. Three participants in the Standard group withdrew: 1 due to time constraints and 2 were unable to be located.

PRIMARY outcome

Timeframe: Immediately after treatment (13 weeks after baseline)

Percentage of study participants who attend 90% (9/10) of the supervised treatment sessions.

Outcome measures

Measure	Movement Pattern Training (MPT) n=23 Participants Treatment: 10 sessions over 12 weeks and a home program provided by a physical therapist. Treatment includes assessment of patient goals and patient education. Movement Pattern Training (MPT) will focus on task-specific training to improve lower extremity movement patterns during basic tasks, such as sit to stand and stairs, and reported patient-specific tasks. Patient education will include instruction in abnormal movement patterns and methods to optimize movement patterns during each task. Exercises will include repeated practice of tasks using optimized movement patterns. Verbal cues and visual aids will be used to assist the participant. Difficulty of the task-specific activities will be progressed by varying repetitions performed, increasing load or changing the support surface. Rehabilitation: Comparison of two rehabilitation approaches	Standard Rehabilitation n=23 Participants Treatment: 10 sessions over 12 weeks and a home program provided by a physical therapist. Treatment includes assessment of patient goals and patient education. For the Standard Rehabilitation, focus will be on progressive lower extremity and trunk strengthening and lower extremity flexibility. Patient education will include instruction to modify intensity, frequency or duration of patient-specific tasks. Using current clinical practice guidelines and previous reports, strengthening and flexibility exercises will be prescribed and progressed by varying the repetitions performed or increasing the load. Rehabilitation: Comparison of two rehabilitation approaches
Percentage of Participants Who Are Adherent to Treatment Attendance	21 Participants	22 Participants

SECONDARY outcome

Timeframe: Immediately after treatment (13 weeks after baseline)

The Hip disability and Osteoarthritis Outcome Score (HOOS) is a patient reported outcome measure to quantify activity limitations due to hip pain. The outcome reported is the change (improvement) in function using the HOOS Activities in Daily Living subscale. Scoring of each subscale ranges from 0-100, with lower scores indicating greater impairment or activity limitation. Change was calculated by subtracting the baseline HOOS Activities in Daily Living from the post-treatment HOOS Activities in Daily Living .

Outcome measures

Measure	Movement Pattern Training (MPT) n=22 Participants Treatment: 10 sessions over 12 weeks and a home program provided by a physical therapist. Treatment includes assessment of patient goals and patient education. Movement Pattern Training (MPT) will focus on task-specific training to improve lower extremity movement patterns during basic tasks, such as sit to stand and stairs, and reported patient-specific tasks. Patient education will include instruction in abnormal movement patterns and methods to optimize movement patterns during each task. Exercises will include repeated practice of tasks using optimized movement patterns. Verbal cues and visual aids will be used to assist the participant. Difficulty of the task-specific activities will be progressed by varying repetitions performed, increasing load or changing the support surface. Rehabilitation: Comparison of two rehabilitation approaches	Standard Rehabilitation n=20 Participants Treatment: 10 sessions over 12 weeks and a home program provided by a physical therapist. Treatment includes assessment of patient goals and patient education. For the Standard Rehabilitation, focus will be on progressive lower extremity and trunk strengthening and lower extremity flexibility. Patient education will include instruction to modify intensity, frequency or duration of patient-specific tasks. Using current clinical practice guidelines and previous reports, strengthening and flexibility exercises will be prescribed and progressed by varying the repetitions performed or increasing the load. Rehabilitation: Comparison of two rehabilitation approaches
Change in Function Using the Hip Disability and Osteoarthritis Outcome Score (HOOS) Activities in Daily Living Subscale From Baseline to Post-treatment (13 Weeks)	12.5 units on a scale Standard Deviation 11.0	12.4 units on a scale Standard Deviation 11.8

SECONDARY outcome

Timeframe: Immediately after treatment (13 weeks after baseline)

The Hip disability and Osteoarthritis Outcome Score (HOOS) is a patient reported outcome measure to quantify activity limitations due to hip pain. The outcome reported is the change (improvement) in function using the HOOSSymptoms subscale. Scoring of each subscale ranges from 0-100, with lower scores indicating greater impairment or activity limitation. Change was calculated by subtracting the baseline HOOSSymptoms from the post-treatment HOOSSymptoms.

Outcome measures

Measure	Movement Pattern Training (MPT) n=22 Participants Treatment: 10 sessions over 12 weeks and a home program provided by a physical therapist. Treatment includes assessment of patient goals and patient education. Movement Pattern Training (MPT) will focus on task-specific training to improve lower extremity movement patterns during basic tasks, such as sit to stand and stairs, and reported patient-specific tasks. Patient education will include instruction in abnormal movement patterns and methods to optimize movement patterns during each task. Exercises will include repeated practice of tasks using optimized movement patterns. Verbal cues and visual aids will be used to assist the participant. Difficulty of the task-specific activities will be progressed by varying repetitions performed, increasing load or changing the support surface. Rehabilitation: Comparison of two rehabilitation approaches	Standard Rehabilitation n=20 Participants Treatment: 10 sessions over 12 weeks and a home program provided by a physical therapist. Treatment includes assessment of patient goals and patient education. For the Standard Rehabilitation, focus will be on progressive lower extremity and trunk strengthening and lower extremity flexibility. Patient education will include instruction to modify intensity, frequency or duration of patient-specific tasks. Using current clinical practice guidelines and previous reports, strengthening and flexibility exercises will be prescribed and progressed by varying the repetitions performed or increasing the load. Rehabilitation: Comparison of two rehabilitation approaches
Change in Hip Disability and Osteoarthritis Outcome Score (HOOS) Symptoms Subscale From Baseline to Post-treatment (13 Weeks)	15.0 units on a scale Standard Deviation 13.2	17.5 units on a scale Standard Deviation 16.2

OTHER_PRE_SPECIFIED outcome

Timeframe: Between Baseline and Immediately after treatment (13 weeks after baseline)

Population: One participant in the Movement Pattern group withdrew due to time constraints. Three participants in the Standard group withdrew: 1 due to time constraints and 2 were unable to be located.

The Hip disability and Osteoarthritis Outcome Score (HOOS) is a patient reported outcome measure to quantify activity limitations due to hip pain. The outcome reported is the change (improvement) in function using the HOOS Pain subscale. Scoring of each subscale ranges from 0-100, with lower scores indicating greater impairment or activity limitation. Change was calculated by subtracting the baseline HOOS Pain from the post-treatment HOOS Pain.

Outcome measures

Measure	Movement Pattern Training (MPT) n=22 Participants Treatment: 10 sessions over 12 weeks and a home program provided by a physical therapist. Treatment includes assessment of patient goals and patient education. Movement Pattern Training (MPT) will focus on task-specific training to improve lower extremity movement patterns during basic tasks, such as sit to stand and stairs, and reported patient-specific tasks. Patient education will include instruction in abnormal movement patterns and methods to optimize movement patterns during each task. Exercises will include repeated practice of tasks using optimized movement patterns. Verbal cues and visual aids will be used to assist the participant. Difficulty of the task-specific activities will be progressed by varying repetitions performed, increasing load or changing the support surface. Rehabilitation: Comparison of two rehabilitation approaches	Standard Rehabilitation n=20 Participants Treatment: 10 sessions over 12 weeks and a home program provided by a physical therapist. Treatment includes assessment of patient goals and patient education. For the Standard Rehabilitation, focus will be on progressive lower extremity and trunk strengthening and lower extremity flexibility. Patient education will include instruction to modify intensity, frequency or duration of patient-specific tasks. Using current clinical practice guidelines and previous reports, strengthening and flexibility exercises will be prescribed and progressed by varying the repetitions performed or increasing the load. Rehabilitation: Comparison of two rehabilitation approaches
Change in Function Using the Hip Disability and Osteoarthritis Outcome Score (HOOS) Pain Subscale From Baseline to Post-treatment (13 Weeks)	18.1 units on a scale Standard Deviation 12.9	19.0 units on a scale Standard Deviation 9.6

OTHER_PRE_SPECIFIED outcome

Timeframe: Between Baseline and Immediately after treatment (13 weeks after baseline)

Population: One participant in the Movement Pattern group withdrew due to time constraints. Three participants in the Standard group withdrew: 1 due to time constraints and 2 were unable to be located.

The Hip disability and Osteoarthritis Outcome Score (HOOS) is a patient reported outcome measure to quantify activity limitations due to hip pain. The outcome reported is the change (improvement) in function using the HOOS Sport subscale. Scoring of each subscale ranges from 0-100, with lower scores indicating greater impairment or activity limitation. Change was calculated by subtracting the baseline HOOS Sport from the post-treatment HOOS Sport.

Outcome measures

Measure	Movement Pattern Training (MPT) n=22 Participants Treatment: 10 sessions over 12 weeks and a home program provided by a physical therapist. Treatment includes assessment of patient goals and patient education. Movement Pattern Training (MPT) will focus on task-specific training to improve lower extremity movement patterns during basic tasks, such as sit to stand and stairs, and reported patient-specific tasks. Patient education will include instruction in abnormal movement patterns and methods to optimize movement patterns during each task. Exercises will include repeated practice of tasks using optimized movement patterns. Verbal cues and visual aids will be used to assist the participant. Difficulty of the task-specific activities will be progressed by varying repetitions performed, increasing load or changing the support surface. Rehabilitation: Comparison of two rehabilitation approaches	Standard Rehabilitation n=20 Participants Treatment: 10 sessions over 12 weeks and a home program provided by a physical therapist. Treatment includes assessment of patient goals and patient education. For the Standard Rehabilitation, focus will be on progressive lower extremity and trunk strengthening and lower extremity flexibility. Patient education will include instruction to modify intensity, frequency or duration of patient-specific tasks. Using current clinical practice guidelines and previous reports, strengthening and flexibility exercises will be prescribed and progressed by varying the repetitions performed or increasing the load. Rehabilitation: Comparison of two rehabilitation approaches
Change in Function Using the Hip Disability and Osteoarthritis Outcome Score (HOOS) Sport Subscale From Baseline to Post-treatment (13 Weeks)	24.4 units on a scale Standard Deviation 18.1	21.6 units on a scale Standard Deviation 15.6

OTHER_PRE_SPECIFIED outcome

Timeframe: Between Baseline and Immediately after treatment (13 weeks after baseline)

Population: One participant in the Movement Pattern group withdrew due to time constraints. Three participants in the Standard group withdrew: 1 due to time constraints and 2 were unable to be located.

The Hip disability and Osteoarthritis Outcome Score (HOOS) is a patient reported outcome measure to quantify activity limitations due to hip pain. The outcome reported is the change (improvement) in function using the HOOS Quality of Life subscale. Scoring of each subscale ranges from 0-100, with lower scores indicating greater impairment or activity limitation. Change was calculated by subtracting the baseline HOOS Quality of Life from the post-treatment HOOS Quality of Life.

Outcome measures

Measure	Movement Pattern Training (MPT) n=22 Participants Treatment: 10 sessions over 12 weeks and a home program provided by a physical therapist. Treatment includes assessment of patient goals and patient education. Movement Pattern Training (MPT) will focus on task-specific training to improve lower extremity movement patterns during basic tasks, such as sit to stand and stairs, and reported patient-specific tasks. Patient education will include instruction in abnormal movement patterns and methods to optimize movement patterns during each task. Exercises will include repeated practice of tasks using optimized movement patterns. Verbal cues and visual aids will be used to assist the participant. Difficulty of the task-specific activities will be progressed by varying repetitions performed, increasing load or changing the support surface. Rehabilitation: Comparison of two rehabilitation approaches	Standard Rehabilitation n=20 Participants Treatment: 10 sessions over 12 weeks and a home program provided by a physical therapist. Treatment includes assessment of patient goals and patient education. For the Standard Rehabilitation, focus will be on progressive lower extremity and trunk strengthening and lower extremity flexibility. Patient education will include instruction to modify intensity, frequency or duration of patient-specific tasks. Using current clinical practice guidelines and previous reports, strengthening and flexibility exercises will be prescribed and progressed by varying the repetitions performed or increasing the load. Rehabilitation: Comparison of two rehabilitation approaches
Change in Function Using the Hip Disability and Osteoarthritis Outcome Score (HOOS) Quality of Life (QOL) Subscale From Baseline to Post-treatment (13 Weeks)	13.1 units on a scale Standard Deviation 13.8	20.9 units on a scale Standard Deviation 16.6

OTHER_PRE_SPECIFIED outcome

Timeframe: Between Baseline and Immediately after treatment (13 weeks after baseline)

Population: One participant in the Movement Pattern group withdrew due to time constraints. Three participants in the Standard group withdrew: 1 due to time constraints and 2 were unable to be located.

The Patient Specific Functional Scale (PSFS), a patient-reported outcome measure of patient-specific activity limitations. Patients are asked to identify "3-5 activities you are unable to do or having difficulties performing due to the pain or symptoms in your hip". Patients then rated level of difficulty from 0-10, 0 indicating they are unable to perform the activity and 10 indicating they are able to perform the activity at their preinjury level. The final score is an average of all scores provided. Change was calculated by subtracting the baseline PSFS from the post-treatment PSFS.

Outcome measures

Measure	Movement Pattern Training (MPT) n=22 Participants Treatment: 10 sessions over 12 weeks and a home program provided by a physical therapist. Treatment includes assessment of patient goals and patient education. Movement Pattern Training (MPT) will focus on task-specific training to improve lower extremity movement patterns during basic tasks, such as sit to stand and stairs, and reported patient-specific tasks. Patient education will include instruction in abnormal movement patterns and methods to optimize movement patterns during each task. Exercises will include repeated practice of tasks using optimized movement patterns. Verbal cues and visual aids will be used to assist the participant. Difficulty of the task-specific activities will be progressed by varying repetitions performed, increasing load or changing the support surface. Rehabilitation: Comparison of two rehabilitation approaches	Standard Rehabilitation n=20 Participants Treatment: 10 sessions over 12 weeks and a home program provided by a physical therapist. Treatment includes assessment of patient goals and patient education. For the Standard Rehabilitation, focus will be on progressive lower extremity and trunk strengthening and lower extremity flexibility. Patient education will include instruction to modify intensity, frequency or duration of patient-specific tasks. Using current clinical practice guidelines and previous reports, strengthening and flexibility exercises will be prescribed and progressed by varying the repetitions performed or increasing the load. Rehabilitation: Comparison of two rehabilitation approaches
Change in Function Using the Patient Specific Functional Scale From Baseline to Post-treatment (13 Weeks)	1.7 units on a scale Standard Deviation 1.7	1.8 units on a scale Standard Deviation 1.8

OTHER_PRE_SPECIFIED outcome

Timeframe: Between Baseline and Immediately after treatment (13 weeks after baseline)

Population: One participant in the Movement Pattern group withdrew due to time constraints. Three participants in the Standard group withdrew: 1 due to time constraints and 2 were unable to be located.

The numeric pain rating scale (NPRS) is a patient-reported outcome measure of pain intensity quantified using a 0-10 scale, 0 indicating the patient perceives no pain and 10 indicating the patient perceives the pain to be "worst pain imaginable". For average NPRS, patients are asked to rate what their pain was over the last week. Change was calculated by subtracting the baseline average NPRS from the post-treatment average NPRS.

Outcome measures

Measure	Movement Pattern Training (MPT) n=22 Participants Treatment: 10 sessions over 12 weeks and a home program provided by a physical therapist. Treatment includes assessment of patient goals and patient education. Movement Pattern Training (MPT) will focus on task-specific training to improve lower extremity movement patterns during basic tasks, such as sit to stand and stairs, and reported patient-specific tasks. Patient education will include instruction in abnormal movement patterns and methods to optimize movement patterns during each task. Exercises will include repeated practice of tasks using optimized movement patterns. Verbal cues and visual aids will be used to assist the participant. Difficulty of the task-specific activities will be progressed by varying repetitions performed, increasing load or changing the support surface. Rehabilitation: Comparison of two rehabilitation approaches	Standard Rehabilitation n=20 Participants Treatment: 10 sessions over 12 weeks and a home program provided by a physical therapist. Treatment includes assessment of patient goals and patient education. For the Standard Rehabilitation, focus will be on progressive lower extremity and trunk strengthening and lower extremity flexibility. Patient education will include instruction to modify intensity, frequency or duration of patient-specific tasks. Using current clinical practice guidelines and previous reports, strengthening and flexibility exercises will be prescribed and progressed by varying the repetitions performed or increasing the load. Rehabilitation: Comparison of two rehabilitation approaches
Change in Average Pain Intensity Quantified by a Numeric Pain Rating Scale (NPRS) From Baseline to Post-treatment (13 Weeks)	-2.9 units on a scale Standard Deviation 1.5	-2.5 units on a scale Standard Deviation 1.9

OTHER_PRE_SPECIFIED outcome

Timeframe: Between Baseline and Immediately after treatment (13 weeks after baseline)

Population: One participant in the Movement Pattern group withdrew due to time constraints. Three participants in the Standard group withdrew: 1 due to time constraints and 2 were unable to be located.

The numeric pain rating scale (NPRS) is a patient-reported outcome measure of pain intensity quantified using a 0-10 scale, 0 indicating the patient perceives no pain and 10 indicating the patient perceives the pain to be "worst pain imaginable". For worst NPRS, patients are asked to rate what was their worst (highest) level of pain was over the last week. Change was calculated by subtracting the baseline worst NPRS from the post-treatment worst NPRS.

Outcome measures

Measure	Movement Pattern Training (MPT) n=22 Participants Treatment: 10 sessions over 12 weeks and a home program provided by a physical therapist. Treatment includes assessment of patient goals and patient education. Movement Pattern Training (MPT) will focus on task-specific training to improve lower extremity movement patterns during basic tasks, such as sit to stand and stairs, and reported patient-specific tasks. Patient education will include instruction in abnormal movement patterns and methods to optimize movement patterns during each task. Exercises will include repeated practice of tasks using optimized movement patterns. Verbal cues and visual aids will be used to assist the participant. Difficulty of the task-specific activities will be progressed by varying repetitions performed, increasing load or changing the support surface. Rehabilitation: Comparison of two rehabilitation approaches	Standard Rehabilitation n=20 Participants Treatment: 10 sessions over 12 weeks and a home program provided by a physical therapist. Treatment includes assessment of patient goals and patient education. For the Standard Rehabilitation, focus will be on progressive lower extremity and trunk strengthening and lower extremity flexibility. Patient education will include instruction to modify intensity, frequency or duration of patient-specific tasks. Using current clinical practice guidelines and previous reports, strengthening and flexibility exercises will be prescribed and progressed by varying the repetitions performed or increasing the load. Rehabilitation: Comparison of two rehabilitation approaches
Change in Worst Pain Intensity Quantified by a Numeric Pain Rating Scale (NPRS) From Baseline to Post-treatment (13 Weeks)	-3.7 units on a scale Standard Deviation 1.8	-3.9 units on a scale Standard Deviation 3.0

OTHER_PRE_SPECIFIED outcome

Timeframe: Between Baseline and 6 months after treatment completion

Population: Six participants, three in each arm, were lost to followup.

The Hip disability and Osteoarthritis Outcome Score (HOOS) is a patient reported outcome measure to quantify activity limitations due to hip pain. The outcome reported is the change (improvement) in function using the HOOS Activity Daily Living (ADL) subscale. Scoring of each subscale ranges from 0-100, with lower scores indicating greater impairment or activity limitation. Change was calculated by subtracting the baseline HOOSADL from the 6 month HOOSADL.

Outcome measures

Measure	Movement Pattern Training (MPT) n=20 Participants Treatment: 10 sessions over 12 weeks and a home program provided by a physical therapist. Treatment includes assessment of patient goals and patient education. Movement Pattern Training (MPT) will focus on task-specific training to improve lower extremity movement patterns during basic tasks, such as sit to stand and stairs, and reported patient-specific tasks. Patient education will include instruction in abnormal movement patterns and methods to optimize movement patterns during each task. Exercises will include repeated practice of tasks using optimized movement patterns. Verbal cues and visual aids will be used to assist the participant. Difficulty of the task-specific activities will be progressed by varying repetitions performed, increasing load or changing the support surface. Rehabilitation: Comparison of two rehabilitation approaches	Standard Rehabilitation n=20 Participants Treatment: 10 sessions over 12 weeks and a home program provided by a physical therapist. Treatment includes assessment of patient goals and patient education. For the Standard Rehabilitation, focus will be on progressive lower extremity and trunk strengthening and lower extremity flexibility. Patient education will include instruction to modify intensity, frequency or duration of patient-specific tasks. Using current clinical practice guidelines and previous reports, strengthening and flexibility exercises will be prescribed and progressed by varying the repetitions performed or increasing the load. Rehabilitation: Comparison of two rehabilitation approaches
Change in Function Using the Hip Disability and Osteoarthritis Outcome Score (HOOS) ADL Subscale From Baseline to 6 Months After Treatment Completion.	90.4 score on a scale Standard Deviation 10.3	92.9 score on a scale Standard Deviation 8.7

OTHER_PRE_SPECIFIED outcome

Timeframe: Between Baseline and 6 months after treatment completion

Population: Six participants, three in each arm, were lost to followup.

The Hip disability and Osteoarthritis Outcome Score (HOOS) is a patient reported outcome measure to quantify activity limitations due to hip pain. The outcome reported is the change (improvement) in function using the HOOS Symptoms subscale. Scoring of each subscale ranges from 0-100, with lower scores indicating greater impairment or activity limitation. Change was calculated by subtracting the baseline HOOSSymptom from the 6 month HOOSSymptom.

Outcome measures

Measure	Movement Pattern Training (MPT) n=20 Participants Treatment: 10 sessions over 12 weeks and a home program provided by a physical therapist. Treatment includes assessment of patient goals and patient education. Movement Pattern Training (MPT) will focus on task-specific training to improve lower extremity movement patterns during basic tasks, such as sit to stand and stairs, and reported patient-specific tasks. Patient education will include instruction in abnormal movement patterns and methods to optimize movement patterns during each task. Exercises will include repeated practice of tasks using optimized movement patterns. Verbal cues and visual aids will be used to assist the participant. Difficulty of the task-specific activities will be progressed by varying repetitions performed, increasing load or changing the support surface. Rehabilitation: Comparison of two rehabilitation approaches	Standard Rehabilitation n=20 Participants Treatment: 10 sessions over 12 weeks and a home program provided by a physical therapist. Treatment includes assessment of patient goals and patient education. For the Standard Rehabilitation, focus will be on progressive lower extremity and trunk strengthening and lower extremity flexibility. Patient education will include instruction to modify intensity, frequency or duration of patient-specific tasks. Using current clinical practice guidelines and previous reports, strengthening and flexibility exercises will be prescribed and progressed by varying the repetitions performed or increasing the load. Rehabilitation: Comparison of two rehabilitation approaches
Change in Function Using the Hip Disability and Osteoarthritis Outcome Score (HOOS) Symptoms Subscale From Baseline to 6 Months After Treatment Completion.	79.8 score on a scale Standard Deviation 14.5	84.0 score on a scale Standard Deviation 12.3

OTHER_PRE_SPECIFIED outcome

Timeframe: Between Baseline and 6 months after treatment completion

Population: Six participants, three in each arm, were lost to followup.

The Hip disability and Osteoarthritis Outcome Score (HOOS) is a patient reported outcome measure to quantify activity limitations due to hip pain. The outcome reported is the change (improvement) in function using the HOOS Pain subscale. Scoring of each subscale ranges from 0-100, with lower scores indicating greater impairment or activity limitation. Change was calculated by subtracting the baseline HOOSPain from the 6 month HOOSPain.

Outcome measures

Measure	Movement Pattern Training (MPT) n=20 Participants Treatment: 10 sessions over 12 weeks and a home program provided by a physical therapist. Treatment includes assessment of patient goals and patient education. Movement Pattern Training (MPT) will focus on task-specific training to improve lower extremity movement patterns during basic tasks, such as sit to stand and stairs, and reported patient-specific tasks. Patient education will include instruction in abnormal movement patterns and methods to optimize movement patterns during each task. Exercises will include repeated practice of tasks using optimized movement patterns. Verbal cues and visual aids will be used to assist the participant. Difficulty of the task-specific activities will be progressed by varying repetitions performed, increasing load or changing the support surface. Rehabilitation: Comparison of two rehabilitation approaches	Standard Rehabilitation n=20 Participants Treatment: 10 sessions over 12 weeks and a home program provided by a physical therapist. Treatment includes assessment of patient goals and patient education. For the Standard Rehabilitation, focus will be on progressive lower extremity and trunk strengthening and lower extremity flexibility. Patient education will include instruction to modify intensity, frequency or duration of patient-specific tasks. Using current clinical practice guidelines and previous reports, strengthening and flexibility exercises will be prescribed and progressed by varying the repetitions performed or increasing the load. Rehabilitation: Comparison of two rehabilitation approaches
Change in Function Using the Hip Disability and Osteoarthritis Outcome Score (HOOS) Pain Subscale From Baseline to 6 Months After Treatment Completion.	1.6 units on a scale Standard Deviation 1.7	1.6 units on a scale Standard Deviation 2.0

OTHER_PRE_SPECIFIED outcome

Timeframe: Between Baseline and 6 months after treatment completion

Population: Six participants, three in each arm, were lost to followup.

The Hip disability and Osteoarthritis Outcome Score (HOOS) is a patient reported outcome measure to quantify activity limitations due to hip pain. The outcome reported is the change (improvement) in function using the HOOS Sport subscale. Scoring of each subscale ranges from 0-100, with lower scores indicating greater impairment or activity limitation. Change was calculated by subtracting the baseline HOOSSPort from the 6 month HOOSSport.

Outcome measures

Measure	Movement Pattern Training (MPT) n=20 Participants Treatment: 10 sessions over 12 weeks and a home program provided by a physical therapist. Treatment includes assessment of patient goals and patient education. Movement Pattern Training (MPT) will focus on task-specific training to improve lower extremity movement patterns during basic tasks, such as sit to stand and stairs, and reported patient-specific tasks. Patient education will include instruction in abnormal movement patterns and methods to optimize movement patterns during each task. Exercises will include repeated practice of tasks using optimized movement patterns. Verbal cues and visual aids will be used to assist the participant. Difficulty of the task-specific activities will be progressed by varying repetitions performed, increasing load or changing the support surface. Rehabilitation: Comparison of two rehabilitation approaches	Standard Rehabilitation n=20 Participants Treatment: 10 sessions over 12 weeks and a home program provided by a physical therapist. Treatment includes assessment of patient goals and patient education. For the Standard Rehabilitation, focus will be on progressive lower extremity and trunk strengthening and lower extremity flexibility. Patient education will include instruction to modify intensity, frequency or duration of patient-specific tasks. Using current clinical practice guidelines and previous reports, strengthening and flexibility exercises will be prescribed and progressed by varying the repetitions performed or increasing the load. Rehabilitation: Comparison of two rehabilitation approaches
Change in Function Using the Hip Disability and Osteoarthritis Outcome Score (HOOS) Sport Subscale From Baseline to 6 Months After Treatment Completion.	83.1 score on a scale Standard Deviation 15.7	84.1 score on a scale Standard Deviation 15.2

OTHER_PRE_SPECIFIED outcome

Timeframe: Between Baseline and 6 months after treatment completion

Population: Six participants, three in each arm, were lost to followup.

The Hip disability and Osteoarthritis Outcome Score (HOOS) is a patient reported outcome measure to quantify activity limitations due to hip pain. The outcome reported is the change (improvement) in function using the HOOS Quality of Life (QOL) subscale. Scoring of each subscale ranges from 0-100, with lower scores indicating greater impairment or activity limitation. Change was calculated by subtracting the baseline HOOSQOL from the 6 month HOOSQOL.

Outcome measures

Measure	Movement Pattern Training (MPT) n=20 Participants Treatment: 10 sessions over 12 weeks and a home program provided by a physical therapist. Treatment includes assessment of patient goals and patient education. Movement Pattern Training (MPT) will focus on task-specific training to improve lower extremity movement patterns during basic tasks, such as sit to stand and stairs, and reported patient-specific tasks. Patient education will include instruction in abnormal movement patterns and methods to optimize movement patterns during each task. Exercises will include repeated practice of tasks using optimized movement patterns. Verbal cues and visual aids will be used to assist the participant. Difficulty of the task-specific activities will be progressed by varying repetitions performed, increasing load or changing the support surface. Rehabilitation: Comparison of two rehabilitation approaches	Standard Rehabilitation n=20 Participants Treatment: 10 sessions over 12 weeks and a home program provided by a physical therapist. Treatment includes assessment of patient goals and patient education. For the Standard Rehabilitation, focus will be on progressive lower extremity and trunk strengthening and lower extremity flexibility. Patient education will include instruction to modify intensity, frequency or duration of patient-specific tasks. Using current clinical practice guidelines and previous reports, strengthening and flexibility exercises will be prescribed and progressed by varying the repetitions performed or increasing the load. Rehabilitation: Comparison of two rehabilitation approaches
Change in Function Using the Hip Disability and Osteoarthritis Outcome Score (HOOS) QOL Subscale From Baseline to 6 Months After Treatment Completion.	73.8 score on a scale Standard Deviation 18.8	75.0 score on a scale Standard Deviation 15.6

OTHER_PRE_SPECIFIED outcome

Timeframe: Between Baseline and 6 months after treatment completion

Population: Six participants, three in each arm, were lost to followup.

The Patient Specific Functional Scale (PSFS), a patient-reported outcome measure of patient-specific activity limitations. Patients are asked to identify "3-5 activities you are unable to do or having difficulties performing due to the pain or symptoms in your hip". Patients then rated level of difficulty from 0-10, 0 indicating they are unable to perform the activity and 10 indicating they are able to perform the activity at their preinjury level. The final score is an average of all scores provided. Change was calculated by subtracting the baseline PSFS from the 6 month PSFS.

Outcome measures

Measure	Movement Pattern Training (MPT) n=20 Participants Treatment: 10 sessions over 12 weeks and a home program provided by a physical therapist. Treatment includes assessment of patient goals and patient education. Movement Pattern Training (MPT) will focus on task-specific training to improve lower extremity movement patterns during basic tasks, such as sit to stand and stairs, and reported patient-specific tasks. Patient education will include instruction in abnormal movement patterns and methods to optimize movement patterns during each task. Exercises will include repeated practice of tasks using optimized movement patterns. Verbal cues and visual aids will be used to assist the participant. Difficulty of the task-specific activities will be progressed by varying repetitions performed, increasing load or changing the support surface. Rehabilitation: Comparison of two rehabilitation approaches	Standard Rehabilitation n=20 Participants Treatment: 10 sessions over 12 weeks and a home program provided by a physical therapist. Treatment includes assessment of patient goals and patient education. For the Standard Rehabilitation, focus will be on progressive lower extremity and trunk strengthening and lower extremity flexibility. Patient education will include instruction to modify intensity, frequency or duration of patient-specific tasks. Using current clinical practice guidelines and previous reports, strengthening and flexibility exercises will be prescribed and progressed by varying the repetitions performed or increasing the load. Rehabilitation: Comparison of two rehabilitation approaches
Change in Function Using the Patient Specific Functional Scale From Baseline to 6 Months After Treatment Completion.	7.2 units on a scale Standard Deviation 2.3	7.1 units on a scale Standard Deviation 2.1

OTHER_PRE_SPECIFIED outcome

Timeframe: Between Baseline and 6 months after treatment completion

Population: Six participants, three in each arm, were lost to followup.

The numeric pain rating scale (NPRS) is a patient-reported outcome measure of pain intensity quantified using a 0-10 scale, 0 indicating the patient perceives no pain and 10 indicating the patient perceives the pain to be "worst pain imaginable". For average NPRS, patients are asked to rate what their pain was over the last week. Change was calculated by subtracting the baseline average NPRS from the 6 month average NPRS.

Outcome measures

Measure	Movement Pattern Training (MPT) n=20 Participants Treatment: 10 sessions over 12 weeks and a home program provided by a physical therapist. Treatment includes assessment of patient goals and patient education. Movement Pattern Training (MPT) will focus on task-specific training to improve lower extremity movement patterns during basic tasks, such as sit to stand and stairs, and reported patient-specific tasks. Patient education will include instruction in abnormal movement patterns and methods to optimize movement patterns during each task. Exercises will include repeated practice of tasks using optimized movement patterns. Verbal cues and visual aids will be used to assist the participant. Difficulty of the task-specific activities will be progressed by varying repetitions performed, increasing load or changing the support surface. Rehabilitation: Comparison of two rehabilitation approaches	Standard Rehabilitation n=20 Participants Treatment: 10 sessions over 12 weeks and a home program provided by a physical therapist. Treatment includes assessment of patient goals and patient education. For the Standard Rehabilitation, focus will be on progressive lower extremity and trunk strengthening and lower extremity flexibility. Patient education will include instruction to modify intensity, frequency or duration of patient-specific tasks. Using current clinical practice guidelines and previous reports, strengthening and flexibility exercises will be prescribed and progressed by varying the repetitions performed or increasing the load. Rehabilitation: Comparison of two rehabilitation approaches
Change in Average Pain Intensity Quantified by a Numeric Pain Rating Scale (NPRS) From Baseline to 6 Months After Treatment Completion.	1.6 units on a scale Standard Deviation 1.7	1.6 units on a scale Standard Deviation 2.0

OTHER_PRE_SPECIFIED outcome

Timeframe: Between Baseline and 6 months after treatment completion

Population: Six participants, three in each arm, were lost to followup.

The numeric pain rating scale (NPRS) is a patient-reported outcome measure of pain intensity quantified using a 0-10 scale, 0 indicating the patient perceives no pain and 10 indicating the patient perceives the pain to be "worst pain imaginable". For worst NPRS, patients are asked to rate what was their worst (highest) level of pain was over the last week. Change was calculated by subtracting the baseline worst NPRS from the 6 month worst NPRS.

Outcome measures

Measure	Movement Pattern Training (MPT) n=20 Participants Treatment: 10 sessions over 12 weeks and a home program provided by a physical therapist. Treatment includes assessment of patient goals and patient education. Movement Pattern Training (MPT) will focus on task-specific training to improve lower extremity movement patterns during basic tasks, such as sit to stand and stairs, and reported patient-specific tasks. Patient education will include instruction in abnormal movement patterns and methods to optimize movement patterns during each task. Exercises will include repeated practice of tasks using optimized movement patterns. Verbal cues and visual aids will be used to assist the participant. Difficulty of the task-specific activities will be progressed by varying repetitions performed, increasing load or changing the support surface. Rehabilitation: Comparison of two rehabilitation approaches	Standard Rehabilitation n=20 Participants Treatment: 10 sessions over 12 weeks and a home program provided by a physical therapist. Treatment includes assessment of patient goals and patient education. For the Standard Rehabilitation, focus will be on progressive lower extremity and trunk strengthening and lower extremity flexibility. Patient education will include instruction to modify intensity, frequency or duration of patient-specific tasks. Using current clinical practice guidelines and previous reports, strengthening and flexibility exercises will be prescribed and progressed by varying the repetitions performed or increasing the load. Rehabilitation: Comparison of two rehabilitation approaches
Change in Worst Pain Intensity Quantified by a Numeric Pain Rating Scale (NPRS) From Baseline to 6 Months After Treatment Completion.	2.8 units on a scale Standard Deviation 2.0	2.6 units on a scale Standard Deviation 2.5

OTHER_PRE_SPECIFIED outcome

Timeframe: Between 12 months after treatment completion

Population: Eight participants, four in each arm, were lost to followup.

The Hip disability and Osteoarthritis Outcome Score (HOOS) is a patient reported outcome measure to quantify activity limitations due to hip pain. The outcome reported is the change (improvement) in function using the HOOS Activity Daily Living (ADL) subscale. Scoring of each subscale ranges from 0-100, with lower scores indicating greater impairment or activity limitation. Change was calculated by subtracting the baseline HOOSADL from the 12 month HOOSADL.

Outcome measures

Measure	Movement Pattern Training (MPT) n=19 Participants Treatment: 10 sessions over 12 weeks and a home program provided by a physical therapist. Treatment includes assessment of patient goals and patient education. Movement Pattern Training (MPT) will focus on task-specific training to improve lower extremity movement patterns during basic tasks, such as sit to stand and stairs, and reported patient-specific tasks. Patient education will include instruction in abnormal movement patterns and methods to optimize movement patterns during each task. Exercises will include repeated practice of tasks using optimized movement patterns. Verbal cues and visual aids will be used to assist the participant. Difficulty of the task-specific activities will be progressed by varying repetitions performed, increasing load or changing the support surface. Rehabilitation: Comparison of two rehabilitation approaches	Standard Rehabilitation n=19 Participants Treatment: 10 sessions over 12 weeks and a home program provided by a physical therapist. Treatment includes assessment of patient goals and patient education. For the Standard Rehabilitation, focus will be on progressive lower extremity and trunk strengthening and lower extremity flexibility. Patient education will include instruction to modify intensity, frequency or duration of patient-specific tasks. Using current clinical practice guidelines and previous reports, strengthening and flexibility exercises will be prescribed and progressed by varying the repetitions performed or increasing the load. Rehabilitation: Comparison of two rehabilitation approaches
Change in Function Using the Hip Disability and Osteoarthritis Outcome Score (HOOS) ADL Subscale From Baseline to 12 Months After Treatment Completion.	91.7 score on a scale Standard Deviation 15.5	92.2 score on a scale Standard Deviation 10.5

OTHER_PRE_SPECIFIED outcome

Timeframe: Between Baseline and 12 months after treatment completion

Population: Eight participants, four in each arm, were lost to followup.

The Hip disability and Osteoarthritis Outcome Score (HOOS) is a patient reported outcome measure to quantify activity limitations due to hip pain. The outcome reported is the change (improvement) in function using the HOOS Symptom subscale. Scoring of each subscale ranges from 0-100, with lower scores indicating greater impairment or activity limitation. Change was calculated by subtracting the baseline HOOSSymptom from the 12 month HOOSSymptom.

Outcome measures

Measure	Movement Pattern Training (MPT) n=19 Participants Treatment: 10 sessions over 12 weeks and a home program provided by a physical therapist. Treatment includes assessment of patient goals and patient education. Movement Pattern Training (MPT) will focus on task-specific training to improve lower extremity movement patterns during basic tasks, such as sit to stand and stairs, and reported patient-specific tasks. Patient education will include instruction in abnormal movement patterns and methods to optimize movement patterns during each task. Exercises will include repeated practice of tasks using optimized movement patterns. Verbal cues and visual aids will be used to assist the participant. Difficulty of the task-specific activities will be progressed by varying repetitions performed, increasing load or changing the support surface. Rehabilitation: Comparison of two rehabilitation approaches	Standard Rehabilitation n=19 Participants Treatment: 10 sessions over 12 weeks and a home program provided by a physical therapist. Treatment includes assessment of patient goals and patient education. For the Standard Rehabilitation, focus will be on progressive lower extremity and trunk strengthening and lower extremity flexibility. Patient education will include instruction to modify intensity, frequency or duration of patient-specific tasks. Using current clinical practice guidelines and previous reports, strengthening and flexibility exercises will be prescribed and progressed by varying the repetitions performed or increasing the load. Rehabilitation: Comparison of two rehabilitation approaches
Change in Function Using the Hip Disability and Osteoarthritis Outcome Score (HOOS) Symptom Subscale From Baseline to 12 Months After Treatment Completion.	79.7 score on a scale Standard Deviation 20.1	84.7 score on a scale Standard Deviation 12.1

OTHER_PRE_SPECIFIED outcome

Timeframe: Between Baseline and 12 months after treatment completion

Population: Eight participants, four in each arm, were lost to followup.

The Hip disability and Osteoarthritis Outcome Score (HOOS) is a patient reported outcome measure to quantify activity limitations due to hip pain. The outcome reported is the change (improvement) in function using the HOOS Pain subscale. Scoring of each subscale ranges from 0-100, with lower scores indicating greater impairment or activity limitation. Change was calculated by subtracting the baseline HOOSPain from the 12 month HOOSPain.

Outcome measures

Measure	Movement Pattern Training (MPT) n=19 Participants Treatment: 10 sessions over 12 weeks and a home program provided by a physical therapist. Treatment includes assessment of patient goals and patient education. Movement Pattern Training (MPT) will focus on task-specific training to improve lower extremity movement patterns during basic tasks, such as sit to stand and stairs, and reported patient-specific tasks. Patient education will include instruction in abnormal movement patterns and methods to optimize movement patterns during each task. Exercises will include repeated practice of tasks using optimized movement patterns. Verbal cues and visual aids will be used to assist the participant. Difficulty of the task-specific activities will be progressed by varying repetitions performed, increasing load or changing the support surface. Rehabilitation: Comparison of two rehabilitation approaches	Standard Rehabilitation n=19 Participants Treatment: 10 sessions over 12 weeks and a home program provided by a physical therapist. Treatment includes assessment of patient goals and patient education. For the Standard Rehabilitation, focus will be on progressive lower extremity and trunk strengthening and lower extremity flexibility. Patient education will include instruction to modify intensity, frequency or duration of patient-specific tasks. Using current clinical practice guidelines and previous reports, strengthening and flexibility exercises will be prescribed and progressed by varying the repetitions performed or increasing the load. Rehabilitation: Comparison of two rehabilitation approaches
Change in Function Using the Hip Disability and Osteoarthritis Outcome Score (HOOS) Pain Subscale From Baseline to 12 Months After Treatment Completion.	1.4 units on a scale Standard Deviation 1.9	1.3 units on a scale Standard Deviation 1.6

OTHER_PRE_SPECIFIED outcome

Timeframe: Between Baseline and 12 months after treatment completion

Population: Eight participants, four in each arm, were lost to followup. One participant in the Standard arm did not complete the HOOS Sport subscale at 12 months.

The Hip disability and Osteoarthritis Outcome Score (HOOS) is a patient reported outcome measure to quantify activity limitations due to hip pain. The outcome reported is the change (improvement) in function using the HOOS Sport subscale. Scoring of each subscale ranges from 0-100, with lower scores indicating greater impairment or activity limitation. Change was calculated by subtracting the baseline HOOSSport from the 12 month HOOSSport.

Outcome measures

Measure	Movement Pattern Training (MPT) n=19 Participants Treatment: 10 sessions over 12 weeks and a home program provided by a physical therapist. Treatment includes assessment of patient goals and patient education. Movement Pattern Training (MPT) will focus on task-specific training to improve lower extremity movement patterns during basic tasks, such as sit to stand and stairs, and reported patient-specific tasks. Patient education will include instruction in abnormal movement patterns and methods to optimize movement patterns during each task. Exercises will include repeated practice of tasks using optimized movement patterns. Verbal cues and visual aids will be used to assist the participant. Difficulty of the task-specific activities will be progressed by varying repetitions performed, increasing load or changing the support surface. Rehabilitation: Comparison of two rehabilitation approaches	Standard Rehabilitation n=18 Participants Treatment: 10 sessions over 12 weeks and a home program provided by a physical therapist. Treatment includes assessment of patient goals and patient education. For the Standard Rehabilitation, focus will be on progressive lower extremity and trunk strengthening and lower extremity flexibility. Patient education will include instruction to modify intensity, frequency or duration of patient-specific tasks. Using current clinical practice guidelines and previous reports, strengthening and flexibility exercises will be prescribed and progressed by varying the repetitions performed or increasing the load. Rehabilitation: Comparison of two rehabilitation approaches
Change in Function Using the Hip Disability and Osteoarthritis Outcome Score (HOOS) Sport Subscale From Baseline to 12 Months After Treatment Completion.	88.5 score on a scale Standard Deviation 17.0	83.3 score on a scale Standard Deviation 18.7

OTHER_PRE_SPECIFIED outcome

Timeframe: Between Baseline and 12 months after treatment completion

Population: Eight participants, four in each arm, were lost to followup. One participant in the Standard arm did not complete the HOOS QOL subscale at 12 months.

The Hip disability and Osteoarthritis Outcome Score (HOOS) is a patient reported outcome measure to quantify activity limitations due to hip pain. The outcome reported is the change (improvement) in function using the HOOS Quality of Life (QOL) subscale. Scoring of each subscale ranges from 0-100, with lower scores indicating greater impairment or activity limitation. Change was calculated by subtracting the baseline HOOSQOL from the 12 month HOOSQOL.

Outcome measures

Measure	Movement Pattern Training (MPT) n=19 Participants Treatment: 10 sessions over 12 weeks and a home program provided by a physical therapist. Treatment includes assessment of patient goals and patient education. Movement Pattern Training (MPT) will focus on task-specific training to improve lower extremity movement patterns during basic tasks, such as sit to stand and stairs, and reported patient-specific tasks. Patient education will include instruction in abnormal movement patterns and methods to optimize movement patterns during each task. Exercises will include repeated practice of tasks using optimized movement patterns. Verbal cues and visual aids will be used to assist the participant. Difficulty of the task-specific activities will be progressed by varying repetitions performed, increasing load or changing the support surface. Rehabilitation: Comparison of two rehabilitation approaches	Standard Rehabilitation n=18 Participants Treatment: 10 sessions over 12 weeks and a home program provided by a physical therapist. Treatment includes assessment of patient goals and patient education. For the Standard Rehabilitation, focus will be on progressive lower extremity and trunk strengthening and lower extremity flexibility. Patient education will include instruction to modify intensity, frequency or duration of patient-specific tasks. Using current clinical practice guidelines and previous reports, strengthening and flexibility exercises will be prescribed and progressed by varying the repetitions performed or increasing the load. Rehabilitation: Comparison of two rehabilitation approaches
Change in Function Using the Hip Disability and Osteoarthritis Outcome Score (HOOS) QOL Subscale From Baseline to 12 Months After Treatment Completion.	76.6 score on a scale Standard Deviation 19.3	74.3 score on a scale Standard Deviation 22.5

OTHER_PRE_SPECIFIED outcome

Timeframe: Between Baseline and 12 months after treatment completion

Population: Eight participants, four in each arm, were lost to followup. One participant in the Standard arm did not complete the PSFS at 12 months.

The Patient Specific Functional Scale (PSFS), a patient-reported outcome measure of patient-specific activity limitations. Patients are asked to identify "3-5 activities you are unable to do or having difficulties performing due to the pain or symptoms in your hip". Patients then rated level of difficulty from 0-10, 0 indicating they are unable to perform the activity and 10 indicating they are able to perform the activity at their preinjury level. The final score is an average of all scores provided. Change was calculated by subtracting the baseline PSFS from the 12 month PSFS.

Outcome measures

Measure	Movement Pattern Training (MPT) n=19 Participants Treatment: 10 sessions over 12 weeks and a home program provided by a physical therapist. Treatment includes assessment of patient goals and patient education. Movement Pattern Training (MPT) will focus on task-specific training to improve lower extremity movement patterns during basic tasks, such as sit to stand and stairs, and reported patient-specific tasks. Patient education will include instruction in abnormal movement patterns and methods to optimize movement patterns during each task. Exercises will include repeated practice of tasks using optimized movement patterns. Verbal cues and visual aids will be used to assist the participant. Difficulty of the task-specific activities will be progressed by varying repetitions performed, increasing load or changing the support surface. Rehabilitation: Comparison of two rehabilitation approaches	Standard Rehabilitation n=18 Participants Treatment: 10 sessions over 12 weeks and a home program provided by a physical therapist. Treatment includes assessment of patient goals and patient education. For the Standard Rehabilitation, focus will be on progressive lower extremity and trunk strengthening and lower extremity flexibility. Patient education will include instruction to modify intensity, frequency or duration of patient-specific tasks. Using current clinical practice guidelines and previous reports, strengthening and flexibility exercises will be prescribed and progressed by varying the repetitions performed or increasing the load. Rehabilitation: Comparison of two rehabilitation approaches
Change in Function Using the Patient Specific Functional Scale From Baseline to 12 Months After Treatment Completion.	8.0 units on a scale Standard Deviation 2.5	7.0 units on a scale Standard Deviation 2.8

OTHER_PRE_SPECIFIED outcome

Timeframe: between Baseline and 12 months after treatment completion

Population: Eight participants, four in each arm, were lost to followup.

The numeric pain rating scale (NPRS) is a patient-reported outcome measure of pain intensity quantified using a 0-10 scale, 0 indicating the patient perceives no pain and 10 indicating the patient perceives the pain to be "worst pain imaginable". For average NPRS, patients are asked to rate what their pain was over the last week. Change was calculated by subtracting the baseline average NPRS from the 12 month average NPRS.

Outcome measures

Measure	Movement Pattern Training (MPT) n=19 Participants Treatment: 10 sessions over 12 weeks and a home program provided by a physical therapist. Treatment includes assessment of patient goals and patient education. Movement Pattern Training (MPT) will focus on task-specific training to improve lower extremity movement patterns during basic tasks, such as sit to stand and stairs, and reported patient-specific tasks. Patient education will include instruction in abnormal movement patterns and methods to optimize movement patterns during each task. Exercises will include repeated practice of tasks using optimized movement patterns. Verbal cues and visual aids will be used to assist the participant. Difficulty of the task-specific activities will be progressed by varying repetitions performed, increasing load or changing the support surface. Rehabilitation: Comparison of two rehabilitation approaches	Standard Rehabilitation n=19 Participants Treatment: 10 sessions over 12 weeks and a home program provided by a physical therapist. Treatment includes assessment of patient goals and patient education. For the Standard Rehabilitation, focus will be on progressive lower extremity and trunk strengthening and lower extremity flexibility. Patient education will include instruction to modify intensity, frequency or duration of patient-specific tasks. Using current clinical practice guidelines and previous reports, strengthening and flexibility exercises will be prescribed and progressed by varying the repetitions performed or increasing the load. Rehabilitation: Comparison of two rehabilitation approaches
Change in Average Pain Intensity Quantified by a Numeric Pain Rating Scale (NPRS) From Baseline to 12 Months After Treatment Completion.	1.4 units on a scale Standard Deviation 1.9	1.3 units on a scale Standard Deviation 1.6

OTHER_PRE_SPECIFIED outcome

Timeframe: Between Baseline and 12 months after treatment completion

Population: Eight participants, four in each arm, were lost to followup.

The numeric pain rating scale (NPRS) is a patient-reported outcome measure of pain intensity quantified using a 0-10 scale, 0 indicating the patient perceives no pain and 10 indicating the patient perceives the pain to be "worst pain imaginable". For worst NPRS, patients are asked to rate what was their worst (highest) level of pain was over the last week. Change was calculated by subtracting the baseline worst NPRS from the 12 month worst NPRS.

Outcome measures

Measure	Movement Pattern Training (MPT) n=19 Participants Treatment: 10 sessions over 12 weeks and a home program provided by a physical therapist. Treatment includes assessment of patient goals and patient education. Movement Pattern Training (MPT) will focus on task-specific training to improve lower extremity movement patterns during basic tasks, such as sit to stand and stairs, and reported patient-specific tasks. Patient education will include instruction in abnormal movement patterns and methods to optimize movement patterns during each task. Exercises will include repeated practice of tasks using optimized movement patterns. Verbal cues and visual aids will be used to assist the participant. Difficulty of the task-specific activities will be progressed by varying repetitions performed, increasing load or changing the support surface. Rehabilitation: Comparison of two rehabilitation approaches	Standard Rehabilitation n=19 Participants Treatment: 10 sessions over 12 weeks and a home program provided by a physical therapist. Treatment includes assessment of patient goals and patient education. For the Standard Rehabilitation, focus will be on progressive lower extremity and trunk strengthening and lower extremity flexibility. Patient education will include instruction to modify intensity, frequency or duration of patient-specific tasks. Using current clinical practice guidelines and previous reports, strengthening and flexibility exercises will be prescribed and progressed by varying the repetitions performed or increasing the load. Rehabilitation: Comparison of two rehabilitation approaches
Change in Worst Pain Intensity Quantified by a Numeric Pain Rating Scale (NPRS) From Baseline to 12 Months After Treatment Completion.	2.1 units on a scale Standard Deviation 2.1	2.5 units on a scale Standard Deviation 2.9

OTHER_PRE_SPECIFIED outcome

Timeframe: Between Baseline and Immediately after treatment (13 weeks after baseline)

Population: This study was a planned secondary analysis using imaging data that was collected at one of the testing site, Washington University Physical Therapy. Imaging data (MRI) was collected from 27 of the 30 participants enrolled at Washington University site. MRI was not available for one participant who did not tolerate the MRI, and MRI data for two participants were excluded due to poor quality scans. Funding for the imaging was provided by the Foundation for Physical Therapy Research.

The outcome reported is the change (increase) in gluteus minimus muscle volume measured in centimeters cubed, using magnetic resonance imaging. Positive scores indicate an increase in volume. Change was calculated by subtracting the baseline muscle volume from the post-treatment muscle volume.

Outcome measures

Measure	Movement Pattern Training (MPT) n=14 Participants Treatment: 10 sessions over 12 weeks and a home program provided by a physical therapist. Treatment includes assessment of patient goals and patient education. Movement Pattern Training (MPT) will focus on task-specific training to improve lower extremity movement patterns during basic tasks, such as sit to stand and stairs, and reported patient-specific tasks. Patient education will include instruction in abnormal movement patterns and methods to optimize movement patterns during each task. Exercises will include repeated practice of tasks using optimized movement patterns. Verbal cues and visual aids will be used to assist the participant. Difficulty of the task-specific activities will be progressed by varying repetitions performed, increasing load or changing the support surface. Rehabilitation: Comparison of two rehabilitation approaches	Standard Rehabilitation n=13 Participants Treatment: 10 sessions over 12 weeks and a home program provided by a physical therapist. Treatment includes assessment of patient goals and patient education. For the Standard Rehabilitation, focus will be on progressive lower extremity and trunk strengthening and lower extremity flexibility. Patient education will include instruction to modify intensity, frequency or duration of patient-specific tasks. Using current clinical practice guidelines and previous reports, strengthening and flexibility exercises will be prescribed and progressed by varying the repetitions performed or increasing the load. Rehabilitation: Comparison of two rehabilitation approaches
Change in Glutueus Minimus Muscle Volume From Baseline to Post-treatment (13 Weeks)	0.0 cm^3 Standard Deviation 7.9	1.0 cm^3 Standard Deviation 6.3

OTHER_PRE_SPECIFIED outcome

Timeframe: Between Baseline and Immediately after treatment (13 weeks after baseline)

The outcome reported is the change (decrease) in the proportion of fatty infiltration within the gluteus maximus muscle, measured by magnetic resonance imaging. A muscle fat index (MFI) was calculated to represent the proportion of fat within a muscle. To be able to analyze fat across the entire length of the muscle (from proximal to distal), muscle length was normalized so that 0% represented the most proximal slice and 100% represented the most distal slice. Mean MFI within every slice was then represented at every 1% of muscle length using spline interpolation.

Outcome measures

Outcome data not reported

OTHER_PRE_SPECIFIED outcome

Timeframe: Between Baseline and Immediately after treatment (13 weeks after baseline)

Population: This study was a planned secondary analysis using imaging data that was collected at one of the testing site, Washington University Physical Therapy. Imaging data (MRI) was collected from 27 of the 30 participants enrolled at Washington University site. MRI was not available for one participant who did not tolerate the MRI, and MRI data for two participants were excluded due to poor quality scans. Funding for the imaging was provided by the Foundation for Physical Therapy Research.

The outcome reported is the change (increase) in gluteus medius muscle volume measured in centimeters cubed, using magnetic resonance imaging. Positive scores indicate an increase in volume. Change was calculated by subtracting the baseline muscle volume from the post-treatment muscle volume.

Outcome measures

Measure	Movement Pattern Training (MPT) n=14 Participants Treatment: 10 sessions over 12 weeks and a home program provided by a physical therapist. Treatment includes assessment of patient goals and patient education. Movement Pattern Training (MPT) will focus on task-specific training to improve lower extremity movement patterns during basic tasks, such as sit to stand and stairs, and reported patient-specific tasks. Patient education will include instruction in abnormal movement patterns and methods to optimize movement patterns during each task. Exercises will include repeated practice of tasks using optimized movement patterns. Verbal cues and visual aids will be used to assist the participant. Difficulty of the task-specific activities will be progressed by varying repetitions performed, increasing load or changing the support surface. Rehabilitation: Comparison of two rehabilitation approaches	Standard Rehabilitation n=13 Participants Treatment: 10 sessions over 12 weeks and a home program provided by a physical therapist. Treatment includes assessment of patient goals and patient education. For the Standard Rehabilitation, focus will be on progressive lower extremity and trunk strengthening and lower extremity flexibility. Patient education will include instruction to modify intensity, frequency or duration of patient-specific tasks. Using current clinical practice guidelines and previous reports, strengthening and flexibility exercises will be prescribed and progressed by varying the repetitions performed or increasing the load. Rehabilitation: Comparison of two rehabilitation approaches
Change in Gluteus Medius Muscle Volume From Baseline to Post-treatment (13 Weeks)	3.1 cm^3 Standard Deviation 7.3	9.6 cm^3 Standard Deviation 8.6

OTHER_PRE_SPECIFIED outcome

Timeframe: Between Baseline and Immediately after treatment (13 weeks after baseline)

Population: This study was a planned secondary analysis using imaging data that was collected at one of the testing site, Washington University Physical Therapy. Imaging data (MRI) was collected from 27 of the 30 participants enrolled at Washington University site. MRI was not available for one participant who did not tolerate the MRI, and MRI data for two participants were excluded due to poor quality scans. Funding for the imaging was provided by the Foundation for Physical Therapy Research.

The outcome reported is the change (increase) in gluteus maximus muscle volume measured in centimeters cubed, using magnetic resonance imaging. Positive scores indicate an increase in volume. Change was calculated by subtracting the baseline muscle volume from the post-treatment muscle volume.

Outcome measures

Measure	Movement Pattern Training (MPT) n=14 Participants Treatment: 10 sessions over 12 weeks and a home program provided by a physical therapist. Treatment includes assessment of patient goals and patient education. Movement Pattern Training (MPT) will focus on task-specific training to improve lower extremity movement patterns during basic tasks, such as sit to stand and stairs, and reported patient-specific tasks. Patient education will include instruction in abnormal movement patterns and methods to optimize movement patterns during each task. Exercises will include repeated practice of tasks using optimized movement patterns. Verbal cues and visual aids will be used to assist the participant. Difficulty of the task-specific activities will be progressed by varying repetitions performed, increasing load or changing the support surface. Rehabilitation: Comparison of two rehabilitation approaches	Standard Rehabilitation n=13 Participants Treatment: 10 sessions over 12 weeks and a home program provided by a physical therapist. Treatment includes assessment of patient goals and patient education. For the Standard Rehabilitation, focus will be on progressive lower extremity and trunk strengthening and lower extremity flexibility. Patient education will include instruction to modify intensity, frequency or duration of patient-specific tasks. Using current clinical practice guidelines and previous reports, strengthening and flexibility exercises will be prescribed and progressed by varying the repetitions performed or increasing the load. Rehabilitation: Comparison of two rehabilitation approaches
Change in Gluteus Maximus Muscle Volume From Baseline to Post-treatment (13 Weeks)	0.3 cm^3 Standard Deviation 32.4	-3.0 cm^3 Standard Deviation 13.3

OTHER_PRE_SPECIFIED outcome

Timeframe: Between Baseline and Immediately after treatment (13 weeks after baseline)

The outcome reported is the change (decrease) in the proportion of fatty infiltration within the gluteus maximus muscle, measured by magnetic resonance imaging. A muscle fat index (MFI) was calculated to represent the proportion of fat within a muscle. To be able to analyze fat across the entire length of the muscle (from proximal to distal), muscle length was normalized so that 0% represented the most proximal slice and 100% represented the most distal slice. Mean MFI within every slice was then represented at every 1% of muscle length using spline interpolation.

Outcome measures

Outcome data not reported

OTHER_PRE_SPECIFIED outcome

Timeframe: Between Baseline and Immediately after treatment (13 weeks after baseline)

The outcome reported is the change (decrease) in the proportion of fatty infiltration within the gluteus maximus muscle, measured by magnetic resonance imaging. A muscle fat index (MFI) was calculated to represent the proportion of fat within a muscle. To be able to analyze fat across the entire length of the muscle (from proximal to distal), muscle length was normalized so that 0% represented the most proximal slice and 100% represented the most distal slice. Mean MFI within every slice was then represented at every 1% of muscle length using spline interpolation.

Outcome measures

Outcome data not reported

Adverse Events

Movement Pattern Training (MPT)

Serious events: 0 serious events

Other events: 0 other events

Deaths: 0 deaths

Standard Rehabilitation

Serious events: 0 serious events

Other events: 0 other events

Deaths: 0 deaths

Serious adverse events

Adverse event data not reported

Other adverse events

Adverse event data not reported

Additional Information

Marcie Harris-Hayes, PT, DPT, MSCI, Professor, Physical Therapy and Orthopaedic Surgery

Washington University School of Medicine

Phone: 314-286-1435

Email: harrisma@wustl.edu

Results disclosure agreements

• Principal investigator is a sponsor employee
• Publication restrictions are in place