Effectiveness of Ultrasound Guided Corticoanesthetic Injection in Carpal Tunnel Syndrome

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

UNKNOWN

Clinical Phase

NA

Total Enrollment

40 participants

Study Classification

INTERVENTIONAL

Study Start Date

2016-10-31

Study Completion Date

2018-12-31

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

Effectiveness of ultrasound guided corticoanesthetic injection in carpal tunnel syndrome treatment comparing two different injection sites. Single-blind randomized trial.

Related Clinical Trials

Explore similar clinical trials based on study characteristics and research focus.

Carpal Tunnel Syndrome - Randomized Clinical Trial Evaluating Effectiveness of Ultrasound in Corticosteroid Injection

NCT02036125

Carpal Tunnel Syndrome

UNKNOWN NA

Pre-operative Sonographic Assessment of The Median Nerve in Carpal Tunnel Syndrome. Does it Affect The Operative Procedure?

NCT03082027

CTS

COMPLETED

Efficacy of Ultrasound-guided Transverse Carpal Ligament Release for Carpal Tunnel Syndrome

NCT06251674

Carpal Tunnel Syndrome

COMPLETED NA

Efficacy of Median Nerve Block Performed Using Echographic Guidance

NCT00835653

Orthopedic

COMPLETED

Ultrasound-Guided Injection vs Intramuscular Steroid for Carpal Tunnel Syndrome

NCT06725420

Carpal Tunnel Syndrome (CTS) Chronic Pain

COMPLETED NA

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

Carpal tunnel syndrome (CTS) is the most common nerve entrapment neuropathy. Six placebo-controlled trials with 393 participants proved corticosteroid injection to be effective in symptom relief. However, all injections were palpation-guided. Therefore, the exact injection site was uncertain. Although three studies comparing palpation and ultrasound (US) guided CTS injection showed US superiority, the optimal injection site for the injectate delivery remains unclear. Some authors believe in thinning of the flexor tenosynovium as the mechanism of the median nerve decompression, and therefore recommend injection between the tendons, away from the nerve. Other authors stress the importance of hydrodissection and direct contact of the injectate with the nerve and suggest injection targeting the median nerve. According to our best knowledge, no study comparing different injection sites for a corticosteroid delivery in CTS has been published in English written literature. The objective of this study was to determine the optimal target site for the corticosteroid delivery in CTS injection.

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Carpal Tunnel Syndrome

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

TRIPLE

Participants Investigators Outcome Assessors

Study Groups

Review each arm or cohort in the study, along with the interventions and objectives associated with them.

Group A

carpal tunnel corticoanesthetic injection between the flexor tendons

Group Type ACTIVE_COMPARATOR

carpal tunnel corticoanesthetic injection

Intervention Type PROCEDURE

Different Injection Sites (between the flexot tendons or around the median nerve with hydrodissection)

Group B

carpal tunnel corticoanesthetic injection next to the median nerve with hydrodissection

Group Type ACTIVE_COMPARATOR

carpal tunnel corticoanesthetic injection

Intervention Type PROCEDURE

Different Injection Sites (between the flexot tendons or around the median nerve with hydrodissection)

Interventions

Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.

carpal tunnel corticoanesthetic injection

Different Injection Sites (between the flexot tendons or around the median nerve with hydrodissection)

Intervention Type PROCEDURE

Other Intervention Names

Discover alternative or legacy names that may be used to describe the listed interventions across different sources.

injetion with corticosteroid and local aneshtetics

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

* primary idiopathic CTS
* symptoms of classic or probable CTS (numbness or tingling in at least 2 of the 4 radial fingers)
* unsuccessful 1-month treatment with wrist splinting
* nerve conduction test results that showed median neuropathy at the wrist

Exclusion Criteria

* previous steroid injection
* diabetes mellitus,
* thyroid disorder
* inflammatory disease
* polyneuropathy
* current pregnancy
* previous carpal tunnel surgery
* severe illness
* inability to respond to questionnaires

Minimum Eligible Age

18 Years

Maximum Eligible Age

70 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Responsible Party

Identify the individual or organization who holds primary responsibility for the study information submitted to regulators.

Responsibility Role SPONSOR

Principal Investigators

Learn about the lead researchers overseeing the trial and their institutional affiliations.

Kamal Mezian, M.D.

Role: PRINCIPAL_INVESTIGATOR

Czech Technical University in Prague, Faculty of Biomedical Engineering, Department of Health Care Disciplines and Population Protection, Sportovců 2311, 272 01 Kladno city, Czech Republic