Trial Outcomes & Findings for Mirthful Laughter and Muscle Soreness / Pain (NCT NCT02896075)

Last Updated: 2021-04-08

Results Overview

The peak force is measured by using a force transducer and applying it to participants' quadriceps. Using data acquisition software the investigators can find the peak force applied.

Recruitment status

COMPLETED

Study phase

Target enrollment

40 participants

Primary outcome timeframe

This was measured at 24 hours after watching either a comedy or documentary film.

Results posted on

2021-04-08

Participant Flow

Participants were recruited from the University student body and the city surrounding the university using flyers

Each intervention included one day of inducing muscle soreness in one leg through eccentric muscle contractions; a second day of testing muscle soreness and pain tolerance and watching a 30-min video (either a comedy or documentary); and a third day of testing muscle soreness and pain tolerance again to see if the effects of the video viewing persisted the next day (i.e., 24 h after the video viewing).

Participant milestones

Participant milestones
Measure	All Study Participants Acting Their Own Controls Each intervention included one day of inducing muscle soreness in one leg through eccentric muscle contractions; a second day of testing muscle soreness and pain tolerance and watching a 30-min video (either a comedy or documentary); and a third day of testing muscle soreness and pain tolerance again to see if the effects of the video viewing persisted the next day (i.e., 24 h after the video viewing).
Overall Study STARTED	40
Overall Study Leg Soreness	40
Overall Study COMPLETED	40
Overall Study NOT COMPLETED	0

Reasons for withdrawal

Withdrawal data not reported

Baseline Characteristics

Mirthful Laughter and Muscle Soreness / Pain

Baseline characteristics by cohort

Baseline characteristics by cohort
Measure	All Study Participants n=40 Participants young healthy people with delayed onset muscle soreness in either the right or left leg will go through the 30 Minute Comedy Video and the 30 Minute Documentary Video. 30 Minute Comedy Video: The intervention is a 30 minute video of a comedy 30 Minute Documentary Video: The intervention is a 30 minute video of an uninteresting documentary
Age, Categorical <=18 years	0 Participants n=5 Participants
Age, Categorical Between 18 and 65 years	40 Participants n=5 Participants
Age, Categorical >=65 years	0 Participants n=5 Participants
Age, Continuous	23 years STANDARD_DEVIATION 4 • n=5 Participants
Sex: Female, Male Female	25 Participants n=5 Participants
Sex: Female, Male Male	15 Participants n=5 Participants
Race (NIH/OMB) American Indian or Alaska Native	0 Participants n=5 Participants
Race (NIH/OMB) Asian	10 Participants n=5 Participants
Race (NIH/OMB) Native Hawaiian or Other Pacific Islander	0 Participants n=5 Participants
Race (NIH/OMB) Black or African American	2 Participants n=5 Participants
Race (NIH/OMB) White	27 Participants n=5 Participants
Race (NIH/OMB) More than one race	0 Participants n=5 Participants
Race (NIH/OMB) Unknown or Not Reported	1 Participants n=5 Participants
Region of Enrollment United States	40 participants n=5 Participants

PRIMARY outcome

Timeframe: This was measured at 24 hours after watching either a comedy or documentary film.

The peak force is measured by using a force transducer and applying it to participants' quadriceps. Using data acquisition software the investigators can find the peak force applied.

Outcome measures

Outcome measures
Measure	Comedy Video n=40 Participants The intervention is watching a 30 minute video of a comedy	Documentary Watching n=40 Participants The intervention is watching a 30 minute video of a documentary
Peak Force of Pain Tolerance Measurement	2 N Standard Deviation 3	21 N Standard Deviation 5

SECONDARY outcome

Timeframe: This was measured at 24 hours after watching either a comedy or documentary video.

The heart rate was using a finger photoplethysmograph.

Outcome measures

Outcome measures
Measure	Comedy Video n=40 Participants The intervention is watching a 30 minute video of a comedy	Documentary Watching n=40 Participants The intervention is watching a 30 minute video of a documentary
Heart Rate	67 beats/minutres Standard Error 12	66 beats/minutres Standard Error 13

SECONDARY outcome

Timeframe: This was measured at 24 hours after watching a comedy or documentary video.

Blood pressure on the brachial artery measured via oscillometric methods

Outcome measures

Outcome measures
Measure	Comedy Video n=40 Participants The intervention is watching a 30 minute video of a comedy	Documentary Watching n=40 Participants The intervention is watching a 30 minute video of a documentary
Blood Pressure Systolic blood pressure	116 mmHg Standard Error 10	116 mmHg Standard Error 10
Blood Pressure Diastolic blood pressure	57 mmHg Standard Error 7	57 mmHg Standard Error 7

Adverse Events

Leg With and Without Delayed Onset Muscle Soreness

Serious events: 0 serious events

Other events: 0 other events

Deaths: 0 deaths

Serious adverse events

Adverse event data not reported

Other adverse events

Adverse event data not reported

Additional Information

Stephanie Lapierre

University of Texas at Austin

Phone: 512-471-8594

Email: [email protected]

Results disclosure agreements

Principal investigator is a sponsor employee
Publication restrictions are in place