Evolution of Myofascial Pain, Post-dry Needling. Repair and Measuring With Elastography, of Myofascial Tissue.

NCT ID: NCT02889991

Last Updated: 2019-02-08

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

77 participants

Study Classification

INTERVENTIONAL

Study Start Date

2016-05-02

Study Completion Date

2017-03-23

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

This study evaluates the deep dry needling technique as a percutaneous technique included in the professional field of physiotherapy.

The project quantifies a significant limit on the number of local twitch responses necessary for the favorable treatment of myofascial pain and analyzes the injury degree and/or the repair of myofascial tissue, with "Elastography".

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

The myofascial shoulder pain caused by myofascial trigger points, is one of the main causes of medical consultation and functional disability in the general population and particularly in the amateur athlete.

Nowadays, many physiotherapists all over the world, study and practice the dry needling as a therapeutic tool for the treatment of myofascial trigger points. The most used modality is the technique described by Hong:

* This technique introduces an acupuncture needle in the skin until reaching the dysfunctional muscle fiber. To do so, it uses maneuvers "fast in" and "fast out" of needle, until the extinction of local twitch responses or the tolerance of the patient.
* The local twitch response is defined as a reflex and transitory contraction of a group of muscle fibers associated with a myofascial trigger points.
* The technique eliminates muscle contractile activity by mechanical interruption of their muscle fibers, mechanism which finishes with the sensitization of nearby nerves and with the start of the nociceptive modulation peripheral, segmental and central.

The dry needling technique, in its eagerness to obtain local twitch responses, pierces the muscle fibers both dysfunctional and normal, the fascial tissue that wraps the myofascial trigger points and also neuro-vascular structures. That is, the treatment of myofascial trigger points with dry needling, makes reference to a mechanical trauma done with a acupuncture needle.

The myofascial tissue injured can suffer repair or regeneration, which is mainly due to the extension of the lesion. The process of healing of a wound is strictly regulated by multiple growth factors and cytokines, which are released into the wound. The alterations that disturb the healing process, can lead to chronic wounds that do not heal or to an excessive fibrosis.

The pathobiological processes, in form of fibrosis, would present changes in stiffness and elasticity of the neo-tissue. The quantitative elastography, is shown as an effective tool to measure the amount of fibrosis, occasioned by repeated percussion of the acupuncture needle on the myofascial tissue.

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Myofascial Pain Syndromes Dry Needling, Technique for the Treatment of the Myofascial Trigger Points Elastography

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Allocation Method

RANDOMIZED

Intervention Model

FACTORIAL

Primary Study Purpose

TREATMENT

Blinding Strategy

DOUBLE

Participants Investigators

Study Groups

Review each arm or cohort in the study, along with the interventions and objectives associated with them.

High Intensity Dry Needling

Maneuver of Input-Output with the acupuncture needle, until the disappearance of local twitch responses or patient tolerance.

Group Type EXPERIMENTAL

High Intensity Dry Needling

Intervention Type OTHER

This technique follows the criteria established by Dr Hong C-Z. This technique is known as "fast in and fast out technique" and uses repeated insertion of the acupuncture needle in the myofascial trigger point, with the aim to get multiple local twitch responses. The technique ends when the local twitch responses disappear.

Low Intensity Dry Needling

Maximum 10 input-output maneuvers with acupuncture needle or maximum 3 local twitch responses or patient tolerance.

Group Type EXPERIMENTAL

Low intensity Dry Needling

Intervention Type OTHER

Technique proposed by the main investigator and based on the studies of Professor Dr. Jay P. Shah and the mechanisms of neuromodulation that transmits us the acupuncture scientific evidence.

Fascial mechanotransduction Dry needling

Maneuver of input, screwing and pulling out of the needle acupuncture.

Group Type EXPERIMENTAL

Fascial Mechanotransduction Dry Needling

Intervention Type OTHER

The Fascial Mechanotransduction Dry Needling Technique, strikes with the acupuncture needle until it reaches and pierces the myofascial trigger point. Then the acupuncture needle is rolled in the connective tissue, which causes an intense coupler that we define as "needle grasp". Finally, the acupuncture needling is pulled-out twice.

The screwing and the two pull-out of the acupuncture needle is performed in the infraspinatus and supraspinatus muscles and we describe it as mechanotransduction cycle. Each cycle lasts 30 seconds and the whole technique lasts 3 minutes per session.

Placebo Dry Needling Technique

Technique is performed with the "Park´s Sham device".

Group Type SHAM_COMPARATOR

Technique Placebo of Dry Needling

Intervention Type OTHER

Technique with a total duration of 3 minutes per session:

* To locate the myofascial trigger points of infraspinatus and supraspinatus muscles and put each bridle on them.
* Monitor longitudinally taut band, with index and middle fingers.
* Percuss with tube and needle placebo (Sham needle) on Infraspinatus.
* Remove the tube and needle placebo from the device. Reintroducing the placebo needle into the tube and strike on the supraspinatus. Repeat this sequence without interruption for 3 minutes.
* Remove the bridles and perform hemostasis with cotton.
* We will give end to the technique placebo of dry needling.

Interventions

Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.

High Intensity Dry Needling

This technique follows the criteria established by Dr Hong C-Z. This technique is known as "fast in and fast out technique" and uses repeated insertion of the acupuncture needle in the myofascial trigger point, with the aim to get multiple local twitch responses. The technique ends when the local twitch responses disappear.

Intervention Type OTHER

Low intensity Dry Needling

Technique proposed by the main investigator and based on the studies of Professor Dr. Jay P. Shah and the mechanisms of neuromodulation that transmits us the acupuncture scientific evidence.

Intervention Type OTHER

Fascial Mechanotransduction Dry Needling

The Fascial Mechanotransduction Dry Needling Technique, strikes with the acupuncture needle until it reaches and pierces the myofascial trigger point. Then the acupuncture needle is rolled in the connective tissue, which causes an intense coupler that we define as "needle grasp". Finally, the acupuncture needling is pulled-out twice.

The screwing and the two pull-out of the acupuncture needle is performed in the infraspinatus and supraspinatus muscles and we describe it as mechanotransduction cycle. Each cycle lasts 30 seconds and the whole technique lasts 3 minutes per session.

Intervention Type OTHER

Technique Placebo of Dry Needling

Technique with a total duration of 3 minutes per session:

* To locate the myofascial trigger points of infraspinatus and supraspinatus muscles and put each bridle on them.
* Monitor longitudinally taut band, with index and middle fingers.
* Percuss with tube and needle placebo (Sham needle) on Infraspinatus.
* Remove the tube and needle placebo from the device. Reintroducing the placebo needle into the tube and strike on the supraspinatus. Repeat this sequence without interruption for 3 minutes.
* Remove the bridles and perform hemostasis with cotton.
* We will give end to the technique placebo of dry needling.

Intervention Type OTHER

Other Intervention Names

Discover alternative or legacy names that may be used to describe the listed interventions across different sources.

Control Group

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

* Unilateral shoulder pain or referred pain pattern of the infraspinatus muscle.
* Pain Intensity with a minimum score of 2 on the Wong-Baker scale, using the homolateral "test hand-back".
* Process time more than 1 and less than 10 weeks.
* Age of 18 years old to 49 years old.
* Written Informed Form.

Exclusion Criteria

* Conventional pharmacological treatment of NSAIDs and / or muscle relaxants, the 48 hours before or during the study.
* Coagulation pathology or anticoagulant therapy.
* Pretreatment with infiltration and / or steroid injections during the last year.
* Physiotherapy Pretreatment, in the cervical region or shoulder girdle during or in the last week taking part in the study.
* Dry needling pretreatment in the cervical region and / or shoulder girdle during or in the last month before taking part in the study.
* History of fracture or dislocation of the shoulder to study, in the last year.
* Dermatological disorders or erosions in the treatment area (infraspinatus fossa).
* Metals allergy such as chromium or nickel.
* Fibromyalgia diagnosis, myelopathy, cervical radiculopathy or neurologic disease.
* Fear of needles.
* Pregnant women.
* Suffering a traumatic accident of the upper extremity and / or cervical-thoracic spine during the study (it will pass to the zero week).
* Medical-legal litigious, by financial compensation.
* Drugs or alcohol abuse / consumption history.
* Cognitive inability to complete the health forms.
Minimum Eligible Age

18 Years

Maximum Eligible Age

49 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

Meet the organizations funding or collaborating on the study and learn about their roles.

FisioAraba Centre Physiotherapy S.C.

UNKNOWN

Sponsor Role collaborator

Toshiba Medical Systems, S.A.

UNKNOWN

Sponsor Role collaborator

Metron Medical Supplies S.L.

UNKNOWN

Sponsor Role collaborator

Novasan, Medical & Health Products

UNKNOWN

Sponsor Role collaborator

University of the Basque Country (UPV/EHU)

OTHER

Sponsor Role lead

Responsible Party

Identify the individual or organization who holds primary responsibility for the study information submitted to regulators.

Francisco jiménez Hidalgo

Physiotherapist

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

Learn about the lead researchers overseeing the trial and their institutional affiliations.

Francisco Jiménez, PT

Role: PRINCIPAL_INVESTIGATOR

University of Basque Country

Locations

Explore where the study is taking place and check the recruitment status at each participating site.

Physiotherapy Centre FISIOARABA

Vitoria-Gasteiz, Alava, Spain

Site Status

Countries

Review the countries where the study has at least one active or historical site.

Spain

References

Explore related publications, articles, or registry entries linked to this study.

Page P. Shoulder muscle imbalance and subacromial impingement syndrome in overhead athletes. Int J Sports Phys Ther. 2011 Mar;6(1):51-8.

Reference Type BACKGROUND
PMID: 21655457 (View on PubMed)

Hong CZ. New trends in myofascial pain syndrome. Zhonghua Yi Xue Za Zhi (Taipei). 2002 Nov;65(11):501-12.

Reference Type BACKGROUND
PMID: 12583512 (View on PubMed)

Hong CZ. Lidocaine injection versus dry needling to myofascial trigger point. The importance of the local twitch response. Am J Phys Med Rehabil. 1994 Jul-Aug;73(4):256-63. doi: 10.1097/00002060-199407000-00006.

Reference Type BACKGROUND
PMID: 8043247 (View on PubMed)

Gerwin RD, Dommerholt J, Shah JP. An expansion of Simons' integrated hypothesis of trigger point formation. Curr Pain Headache Rep. 2004 Dec;8(6):468-75. doi: 10.1007/s11916-004-0069-x.

Reference Type BACKGROUND
PMID: 15509461 (View on PubMed)

Cotchett MP, Landorf KB, Munteanu SE. Effectiveness of dry needling and injections of myofascial trigger points associated with plantar heel pain: a systematic review. J Foot Ankle Res. 2010 Sep 1;3:18. doi: 10.1186/1757-1146-3-18.

Reference Type BACKGROUND
PMID: 20807448 (View on PubMed)

Huang YT, Lin SY, Neoh CA, Wang KY, Jean YH, Shi HY. Dry needling for myofascial pain: prognostic factors. J Altern Complement Med. 2011 Aug;17(8):755-62. doi: 10.1089/acm.2010.0374. Epub 2011 Jul 11.

Reference Type BACKGROUND
PMID: 21745098 (View on PubMed)

Ay S, Evcik D, Tur BS. Comparison of injection methods in myofascial pain syndrome: a randomized controlled trial. Clin Rheumatol. 2010 Jan;29(1):19-23. doi: 10.1007/s10067-009-1307-8. Epub 2009 Oct 20.

Reference Type BACKGROUND
PMID: 19838864 (View on PubMed)

Tough EA, White AR, Cummings TM, Richards SH, Campbell JL. Acupuncture and dry needling in the management of myofascial trigger point pain: a systematic review and meta-analysis of randomised controlled trials. Eur J Pain. 2009 Jan;13(1):3-10. doi: 10.1016/j.ejpain.2008.02.006. Epub 2008 Apr 18.

Reference Type BACKGROUND
PMID: 18395479 (View on PubMed)

Hsieh YL, Yang SA, Yang CC, Chou LW. Dry needling at myofascial trigger spots of rabbit skeletal muscles modulates the biochemicals associated with pain, inflammation, and hypoxia. Evid Based Complement Alternat Med. 2012;2012:342165. doi: 10.1155/2012/342165. Epub 2012 Dec 23.

Reference Type BACKGROUND
PMID: 23346198 (View on PubMed)

Tekin L, Akarsu S, Durmus O, Cakar E, Dincer U, Kiralp MZ. The effect of dry needling in the treatment of myofascial pain syndrome: a randomized double-blinded placebo-controlled trial. Clin Rheumatol. 2013 Mar;32(3):309-15. doi: 10.1007/s10067-012-2112-3. Epub 2012 Nov 9.

Reference Type BACKGROUND
PMID: 23138883 (View on PubMed)

Midwood KS, Williams LV, Schwarzbauer JE. Tissue repair and the dynamics of the extracellular matrix. Int J Biochem Cell Biol. 2004 Jun;36(6):1031-7. doi: 10.1016/j.biocel.2003.12.003.

Reference Type BACKGROUND
PMID: 15094118 (View on PubMed)

Jarvinen TA, Jarvinen TL, Kaariainen M, Kalimo H, Jarvinen M. Muscle injuries: biology and treatment. Am J Sports Med. 2005 May;33(5):745-64. doi: 10.1177/0363546505274714.

Reference Type BACKGROUND
PMID: 15851777 (View on PubMed)

Domingo A, Mayoral O, Monterde S, Santafe MM. Neuromuscular damage and repair after dry needling in mice. Evid Based Complement Alternat Med. 2013;2013:260806. doi: 10.1155/2013/260806. Epub 2013 Apr 9.

Reference Type BACKGROUND
PMID: 23662122 (View on PubMed)

Sikdar S, Shah JP, Gebreab T, Yen RH, Gilliams E, Danoff J, Gerber LH. Novel applications of ultrasound technology to visualize and characterize myofascial trigger points and surrounding soft tissue. Arch Phys Med Rehabil. 2009 Nov;90(11):1829-38. doi: 10.1016/j.apmr.2009.04.015.

Reference Type BACKGROUND
PMID: 19887205 (View on PubMed)

Langevin HM, Nedergaard M, Howe AK. Cellular control of connective tissue matrix tension. J Cell Biochem. 2013 Aug;114(8):1714-9. doi: 10.1002/jcb.24521.

Reference Type BACKGROUND
PMID: 23444198 (View on PubMed)

Ingber DE, Wang N, Stamenovic D. Tensegrity, cellular biophysics, and the mechanics of living systems. Rep Prog Phys. 2014 Apr;77(4):046603. doi: 10.1088/0034-4885/77/4/046603.

Reference Type BACKGROUND
PMID: 24695087 (View on PubMed)

Shah JP, Gilliams EA. Uncovering the biochemical milieu of myofascial trigger points using in vivo microdialysis: an application of muscle pain concepts to myofascial pain syndrome. J Bodyw Mov Ther. 2008 Oct;12(4):371-384. doi: 10.1016/j.jbmt.2008.06.006. Epub 2008 Aug 13.

Reference Type BACKGROUND
PMID: 19083696 (View on PubMed)

Leung L. Neurophysiological basis of acupuncture-induced analgesia--an updated review. J Acupunct Meridian Stud. 2012 Dec;5(6):261-70. doi: 10.1016/j.jams.2012.07.017. Epub 2012 Aug 22.

Reference Type BACKGROUND
PMID: 23265077 (View on PubMed)

Other Identifiers

Review additional registry numbers or institutional identifiers associated with this trial.

M10_2015_142_GRANADOS

Identifier Type: -

Identifier Source: org_study_id

More Related Trials

Additional clinical trials that may be relevant based on similarity analysis.