Rates DMBT1 ( Glycoprotein) in Sputum of CF Patients With Pseudomonas Aeruginosa

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

TERMINATED

Total Enrollment

1 participants

Study Classification

OBSERVATIONAL

Study Start Date

2016-03-23

Study Completion Date

2022-03-31

Brief Summary

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Rates of DMBT1 (Glycoprotein like) in Sputum of CF Patients with or without may be different according to their Pseudomonas Aeruginosa chronic colonization status. The aim of this study is to compare rates of DMBT1 (Glycoprotein like) in Sputum of CF patients with or without a Pseudomonas Aeruginosa chronic colonization.

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Detailed Description

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Rates of DMBT1 (Deleted in Malignant Brain Tumor 1) will be compared between 2 groups of 30 CF patients : group 1 : with Pseudomonas Aeruginosa chronic colonization and group 2 30 CF patients without Pseudomonas Aeruginosa chronic colonization.

Conditions

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Malignant Brain Tumor

Study Design

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Observational Model Type

CASE_CONTROL

Study Time Perspective

PROSPECTIVE

Study Groups

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group 1

CF patients with Pseudomonas aeruginosa chronic colonization.

No interventions assigned to this group

group 2

CF patients without a Pseudomonas aeruginosa chronic colonization.

No interventions assigned to this group

Eligibility Criteria

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Inclusion Criteria

* CF patient 6 years
* Availability of sputum
* Signed Informed consent

Exclusion Criteria

* Cardiac insufficiency
* Anti-inflammatory drugs on going
* Oral corticosteroid therapy
* Inhaled corticosteroids during the two weeks before inclusion,
* Patient awaiting lung transplantation
* Patient with a past history of heart/lung transplantation
* Patient with a sputum examination positive for : atypical mycobacteria, Burkholderia cepacia, Stenotrophomonas maltophilia,
* Patient chronically colonized with multiresistant Pseudomonas aeruginosa
* Orkambi© or Kalydeco© therapy
* Change of the CF treatment during the last 4 weeks +/- 2 days before inclusion : corticosteroid, pancreatic extracts, antisecretory drugs...

Minimum Eligible Age

6 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No