Evaluation of a Diabetes Treatment and Education Program for Insulin Pump Therapy (INPUT)

NCT ID: NCT02868931

Last Updated: 2017-11-28

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

268 participants

Study Classification

INTERVENTIONAL

Study Start Date

2016-04-01

Study Completion Date

2017-03-31

Brief Summary

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This study is a randomized, controlled, prospective trial with a 6-month follow-up. A newly developed treatment and education programme for diabetic patients with an insulin pump therapy (INPUT) will be tested compared to a waiting group. Primary outcome variable is the difference in glycemic control between baseline and the 6-month follow-up. Secondary outcome variables are: severe hypoglycaemia, diabetes-related distress, depressive symptoms, health-related quality of life, diabetes empowerment, self-care behavior, hypoglycemia awareness, and attitudes towards insulin pump therapy.

Detailed Description

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INPUT is a self-management-based treatment and education program for diabetic patients with an insulin pump (CSII). It is designed to empower patients to adequately perform their therapy in daily life and to integrate their diabetes and their insulin pump into their lifes in order to enhance quality of life.

INPUT ist tested in an randomized controlled trial (RCT) with a waiting-list control group since no certified and effective treatment and education program for CSII exists.

This study is a multi-center study. Study centers are specialized diabetes practices throughout Germany. Patients will be approached by their respective practice and informed about the study. Study measurements as well as the conduct of INPUT will take place at the respective practice.

Baseline measurement will take place 2 weeks prior to the beginning of INPUT. After completion of baseline measurement, all patients from one study center will be randomized centrally by the Research Institute of the Diabetes Academy Mergentheim (FIDAM). 2 weeks and 6 months after the completion of INPUT, follow-up measurements will be conducted at the respective study center.

HbA1c as a marker of glycemic control will be analyzed in a central laboratory. Secondary outcome measures will be assessed via psychometrically tested questionnaires, Case Reports Forms, or patient files.

Conditions

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Diabetes Mellitus

Keywords

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self-management empowerment treatment and education program insulin pump diabetes education

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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INPUT

INPUT consists of 12 lessons comprising all relevant information in order to treat diabetes with an insulin pump. Patients learn to effectively use the different features of their pump in order to improve not only glycemic control but also to improve the implementation of pump therapy in daily life. Psychological and motivational aspects of living with diabetes and living with an insulin pump are addressed as well.

Group Type EXPERIMENTAL

INPUT

Intervention Type BEHAVIORAL

Treatment and education program based on the self-management theory of behavioral medicine.

The program is delivered by certified and specially trained diabetes educators.

Waiting list

Patients are randomly assigned to the waiting list. After completion of the 6-month follow-up, these patients will also receive training with INPUT.

Group Type NO_INTERVENTION

No interventions assigned to this group

Interventions

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INPUT

Treatment and education program based on the self-management theory of behavioral medicine.

The program is delivered by certified and specially trained diabetes educators.

Intervention Type BEHAVIORAL

Other Intervention Names

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treatment and education program for INsulin PUmp Therapy

Eligibility Criteria

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Inclusion Criteria

* Existing insulin pump therapy
* Prior participation in a structured diabetes education program
* HbA1c ≥ 7,5% but ≤ 13%
* Ability to understand, speak and write German language
* informed consent (if necessary, informed consent of the parents)

Exclusion Criteria

* Diabetes duration \< 1 year
* severe organic disease preventing a regular participation in the training course
* pregnancy
* severe cognitive impairment
* current treatment of psychiatric disorder
* renal disease requiring dialysis
Minimum Eligible Age

16 Years

Maximum Eligible Age

75 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Berlin-Chemie

UNKNOWN

Sponsor Role collaborator

Norbert Hermanns

OTHER

Sponsor Role lead

Responsible Party

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Norbert Hermanns

CEO

Responsibility Role SPONSOR_INVESTIGATOR

Principal Investigators

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Norbert Hermanns, PhD

Role: PRINCIPAL_INVESTIGATOR

Forschungsinstitut der Diabetes Akademie Mergentheim (FIDAM GmbH)

Locations

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Diabetologische Schwerpunktpraxis Neuss

Neuss, , Germany

Site Status

Countries

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Germany

References

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Ehrmann D, Kulzer B, Schipfer M, Lippmann-Grob B, Haak T, Hermanns N. Efficacy of an Education Program for People With Diabetes and Insulin Pump Treatment (INPUT): Results From a Randomized Controlled Trial. Diabetes Care. 2018 Dec;41(12):2453-2462. doi: 10.2337/dc18-0917. Epub 2018 Oct 10.

Reference Type DERIVED
PMID: 30305343 (View on PubMed)

Other Identifiers

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NH012016

Identifier Type: -

Identifier Source: org_study_id