Perception of Objects and Natural Scenes in People With Vision Loss (ACTIVIS)

NCT ID: NCT02862405

Last Updated: 2016-08-11

Basic Information

• Recruitment Status: COMPLETED
• Total Enrollment: 260 participants
• Study Classification: OBSERVATIONAL
• Study Start Date: 2011-03-31
• Study Completion Date: 2015-03-31

Brief Summary

The loss of central vision causes difficulty not only in reading but also in faces recognition, and in particular in the identification of facial expression, objects or spaces. These visual deficits have been mainly studied in relation with reading, which is the main complaint of these kind of patients. However, there are not enough data regarding perception of objects and spaces in this population. Then, the objectives are to study the visual-spatial abilities in individuals with vision loss, and altered cognitive processes, (2) to develop clinics tools for early detection and quantification of visual-spatial deficits and (3)to understand the capacities of normal peripheral vision in order to test the possibility of potential training for use of peripheral vision when central vision is impaired by an ophthalmic pathology.

Conditions

Vision Loss

Study Design

• Observational Model Type: CASE_CONTROL
• Study Time Perspective: CROSS_SECTIONAL

Study Groups

Patients with loss of central vision

Patients coming in ophthalmic consultation will be selected for the study. The diagnosis of this disease is based on clinical examination, and imaging of the retina.Patients with only loss of central vision will be selected.

vision tests

Intervention Type: OTHER

Patients with loss of peripheral vision

Patients coming in ophthalmic consultation will be selected for the study. Patients with loss of peripheral vision will be selected on the bases of presence of tunnel vision.

vision tests

Intervention Type: OTHER

Control group

Patients without loss of vision.

vision tests

Intervention Type: OTHER

Interventions

vision tests

Intervention Type: OTHER

Eligibility Criteria

Inclusion Criteria

• Patients with eye disease causing loss of central or peripheral vision
• French speakers
• Age between 18 and 90 years old
• Written consent
• Health insurance

• Sex and age matched controls (+/- 5 years)
• French speakers
• Normal visual examination with visual acuity of min 9/10

Exclusion Criteria

• Psychiatric disease or neurological pathologies
• Communication difficulties (deafness / mutism)
• Drug treatment altering concentration
• Mental deterioration with MMS <24
• Alcoholism or addiction to drugs
• Persons under guardianship

• Minimum Eligible Age: 18 Years
• Maximum Eligible Age: 90 Years
• Eligible Sex: ALL
• Accepts Healthy Volunteers: Yes

Sponsors

University Hospital, Lille

OTHER

Sponsor Role: collaborator

Lille Catholic University

OTHER

Sponsor Role: lead

Responsible Party

Responsibility Role: SPONSOR

Principal Investigators

Thi Ha Chau Tran, MD

Role: PRINCIPAL_INVESTIGATOR

Hospital of the Lille Catholic Institute

Other Identifiers

RC-P009

Identifier Type: -

Identifier Source: org_study_id